Nanoparticles encapsulate key substances from riceberry extract using nanotransethosome technology and a specific manufacturing process.

Abstract

OCR 09WP 23 / 06 / 2569 Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology. The manufacturing process for these particles involves a mixture of ingredients including riceberry extract, plant-based fats, and other fats. Animals; surfactants such as sorbitan esters and polysorbates. The developed transethosome nanoparticles exhibit good stability and homogeneous dispersion in water. No separation occurs when left at room temperature. The particles have good dispersion, are of similar size throughout the system, and... Furthermore, with particle sizes smaller than 200 nanometers, it was found that the developed technology can increase absorption. The active compounds from riceberry extract are absorbed more effectively in the digestive system than those prepared in solution form. The key compounds from the riceberry extract, encapsulated in trans-ethosome nanoparticles, have antioxidant properties.

Claims

OCR 09WP 23 / 06 / 2569 1. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology. It contains the following ingredients: Riceberry extract, 25.0 - 40.0% by weight. - Vegetable fat 1.0 - 5.0 percent by weight. - Animal fat: 0.5 - 2.0 percent by weight. - Surfactant, sorbitan esters, 2.0 - 5.0% by weight. - Surfactants: Polysorbates, 2.0 - 5.0% by weight. - Water: 43.0 - 69.5% by weight.

2. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following... Patent No. 1, where Riceberry extract is obtained by extracting with 50-95% ethanol by volume. Propylene glycol 3. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following... Hold either of the first or second rights, where plant-based fats are selectable from lecithin, vegetable oil, and glycolipids. (Glycolipid) or a mixture of two or more of the aforementioned phospholipids.

4. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following... Hold one of three rights (1 through 3), where animal fats are selectable from cholesterol, oils, etc. Animals, glycolipids, or mixtures of two or more such phospholipids.

5. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following... It holds one of four rights (1 through 4) in which the surfactant sorbitan esters are selective. Obtained from Span 20, Span 60, and Span 80, or a blend of sorbitan. Two or more such esters (Sorbitan esters) 6. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following points. Holding one of five rights (1 through 5), the surfactant polysorbates can be selected from the following options. Tween 20, Tween 60, and Tween 80, or a mixture of polysorbate. (Polysorbates) of two or more types as mentioned above.

7. Nanoparticles encapsulate key substances from riceberry extract using nanotrans-ethosome technology, as per the following... Possessing any one of the 1 through 6 rights, where water can be selected from distilled water, boiled water, filtered water, mineral water, or a mixture. Containing two or more types of liquids.

8. Method for producing nanoparticles that encapsulate active ingredients from riceberry extract using nanotransfer technology. Ethosomal determination, according to any one of the seven claims, consists of the following steps: A. Combine riceberry extract, plant-based fats, animal fats, and the surfactant sorbitanase. Sorbitan esters are stirred at a speed of 200-500 rpm while being heated to 80-90 degrees Celsius. Celsius, until all substances dissolve and become homogeneous (oil phase). B. Dissolve the polysorbate surfactant in water and stir at a speed of 200-500 rpm. Revolutions per minute, heating to 80-90 degrees Celsius until all the substances melt and become a homogeneous mixture. (Water cycle) C. Mix the water phase (a) into the oil phase (b) and stir continuously for at least [time period]. 30-60 minutes at a speed of 500-1,000 revolutions per minute, heating to 70-80 degrees Celsius until... All the substances dissolve together to form nanoethosomes. d. The prepared nanoethosomes are then reduced in size by spinning them in a high-speed homogenizer. Homogenize at a speed of 5,000 - 10,000 revolutions per minute for 5 - 20 minutes to obtain the resulting solution. To be homogeneous and have the desired nanoparticle size.