REAL-TIME NANOPARTICLE GUIDANCE AND IMAGING SYSTEM

Abstract

The invention relates to a system for the real-time orientation and imaging of nanoparticles within the body using an active magnetic field.

Description

1 TARIFF REAL-TIME NANOPARTICLE GUIDANCE AND IMAGING SYSTEM TECHNICAL AREA 5 The invention uses an active magnetic field to instantly deliver nanoparticles into the body. It is related to the orientation and display system. PREVIOUS TECHNIQUE In cancer treatment, drugs are used to target the cancerous area. When the nanoparticles used are injected into the patient's body, they target the cancerous area. Arrival time is of vital importance for the patient, because nanoparticles penetrate the body. the amount of medication he / she is carrying in relation to the time he / she has spent inside is lost. Therefore, visualization of nanoparticles is lost during treatment. informing the doctor about the status of the medications in the patient's body and 15 This helps to make the treatment more effective. In the literature, three magnetic field generators are fixed in nanoparticle targeting systems. It has been used as such, and nanoparticles have been passively targeted. Passively The greatest advantage of targeting using an active magnetic field compared to targeting is... The disadvantage is that the time nanoparticles spend inside the body increases, and this 20 Therefore, the amount of drug they carry decreases according to the White-Noyes equation. Passive Another disadvantage of targeting is that it cannot be directed in real time, and It is not visible. Also, in the literature, using navigation data... a system that sends feedback on the position of nanoparticles and visualizes them. It is not available in the system. 25 Also, during cancer treatment, the patient's body may react unexpectedly to the medication. When a reaction occurs, the only way to stop this reaction using known techniques is... The goal is to wait for the drug to be eliminated from the body. This is the situation for the patient during the treatment process. This poses a serious problem for their life, and the medication in the patient's body is momentarily affected. It cannot be removed from the body. Indeed, it is much more difficult than chemotherapy and radiotherapy. 30 effective, targeting only the cancerous area and affecting that area, it delivers the necessary drugs. capable of carrying and subsequently releasing carrier agents in a controlled manner from within the body. There is a great need for an instantaneous nanoparticle production system. 2 A BRIEF DESCRIPTION OF THE INVENTION The invention consists of four magnetic field generators and their connected linear structures. actively activating nanoparticles using an electromotor system that provides movement It can direct. The magnetic field used in the directional system. Since the position of the generators with nanoparticles was known from the outset, the invention is 5 The next position of the nanoparticles is determined by the electromotor complex. This is provided. In the imaging section, it is obtained from a nanoparticle guiding device. Using this obtained location information and the anatomical structure of the patient's body, the software... They are matched via this method and the nanoparticles are instantly transferred inside the patient's body. an image is being created. This image is displayed on a smart device worn by the doctor performing the operation. The nanoparticles are transferred to the glasses. Using smart glasses, the nanoparticles are transferred to the doctor's eye. synchronized with their movements and including at least one of the doctor's brainwaves, It can be guided in real-time via electroencephalography (EEG). LIST OF FIGURES 15 Figure 1. Front view of the nanoparticle orientation device. Figure 2. General view of the nanoparticle orientation device. Figure 3. General view of the electric motor system. Figure 4. Front view of the smart glasses. The Correspondences of the Numbers Shown in the Figures 1. The section where the patient is located 2. Electric motor system 3. The case that holds the system together. Coil 25 5. Cooling block 6. Motor of the electric motor system 7. Bearing 8. Linear motion shaft 9. Worm gear 30 10. Connection point of the electric motor system to the chassis. 11. Connection piece between the worm gear and the motor. 12. Image projection system 13. Eye-tracking camera 3 14. The main case to which the parts are connected. 15. Integrated circuit (flex sensor, communication module, charging unit, electroencephalography sensor, battery system, accelerometer and microprocessor) DETAILED DESCRIPTION OF THE INVENTION The invention includes the patient's compartment (1), the electromotor system (2), and the system as a holding case (3), coil (4), cooling block (5), motor of the electric motor system (6), bearing (7), linear motion shaft (8), worm gear (9), electric motor system connection point with the casing (10), connection part of the worm gear and motor (11), image 10 reflection system (12), eye-tracking camera (13), parts connected general case (14) and integrated circuit (15) (communication module, charging unit, It consists of electroencephalography sensor and decision control unit components. The invention essentially consists of two different steering systems. The first one... Part 15 is a nanoparticle directing device and is operated manually. At least one electric motor system (2) on the steering device, magnetic field producing coil (4), cooling block (5) that cools the coils, part where the patient is located (1) and includes the case (3) that holds the system together. The second part is where real-time navigation data is received. Real-time. The nanoparticle aiming device has coils (4) on it, and 20 coils connected to it. nanoparticles with linear motion of the electromotor system (2), Moving in 3D based on position data from navigation systems. It possesses this property. Therefore, it can instantly direct nanoparticles. There are two different devices from which the routing data is received. These devices have something in common. A communication module was used and location data from the devices was received. 25 The data is transferred wirelessly to the nanoparticle guidance system. The data is transmitted in this way, and devices connect to each other via the Internet of Things. This system allows the doctor to establish the environment where the treatment will take place. It is not necessary to have one. The first device is in the form of a glove and has at least one on it. Flex sensors (optimum 5 units), one communication module, battery system, acceleration 30 a sensor is an integrated circuit containing at least one avionics sensor and a microprocessor (15) includes. The doctor removes nanoparticles from the patient's body from space. independently directing, flexing hand movements made through gloves integrated circuit (15) through sensors and accelerometer on it 4 It analyzes the incoming data using its microprocessor and... Instantaneous nanoparticle targeting via the communication module located there. It sends it to the system. The second device is in the form of smart glasses and has at least one The electroencephalography (EEG) sensor and communication module monitor the doctor's eye movements. The tracking camera (13) shows the instantaneous position of the nanoparticles inside the body. from the image projection system (12) and microcontroller and power unit It consists of two different types of glasses that can direct nanoparticles. It has, firstly, a camera located on it that tracks the doctor's eye movements. (13) This is done via. Here the camera follows the doctor’s eye movements. and position data of nanoparticles based on eye movements Communication module nanoparticle by analyzing via microcontroller The nanoparticles are sent to the guiding device and are moved instantaneously. The second method involves an electroencephalogram (EEG) located on the glasses. The directional data from the sensor is analyzed via the microcontroller. 15 After this, the communication module is used to transmit the nanoparticles via brain waves. Real-time guidance is provided. The image on the smart glasses initial position of nanoparticles via reflection system (12) and magnetic field generating coils located on the nanoparticle guiding device (4) Since the next position it will go to with its movement is known, this information is used to 20 The instantaneous image of nanoparticles inside the body is reflected by the glasses. The image appears in front of the doctor's eyes via the system. Thus, the doctor... This allows for the real-time orientation and visualization of nanoparticles. 30

Claims

SYSTEMS 1. It is an instantaneous nanoparticle targeting system, and its feature is; - the part where the patient is located (1), - the case that holds the system together (3), 5 - at least one electric motor system (2), - electric motor system (2) electric motor system located inside motor (6), bearing (7), linear motion shaft (8), worm gear (9), Connection point of the electric motor system with the housing (10) and with the worm gear motor connection part (11), 10 - coil that generates magnetic field (4), - heatsink block (5) that cools the coils, - a glove-shaped device with at least one flex sensor on it, communication module, battery system, accelerometer, at least one avionics a sensor, a microprocessor containing integrated circuit (15) with a nanoparticle targeting device, Communication between the targeting device and the nanoparticle targeting device. instantaneous connection characterized by establishing a connection via the module It is a nanoparticle delivery system.

2. It is an instantaneous nanoparticle targeting system according to claim 1, and its feature is; device 20 coils (4) on it, electric motor to which the coils are connected directing nanoparticles with linear motions of the system (2) Ability to move in 3D based on position data from the systems. It is an instantaneous nanoparticle targeting system characterized by its properties.

3. It is an instantaneous nanoparticle delivery system according to Claim 1, and its feature is that the doctor 25 It detects the hand movements made through flex sensors and accelerometers. the microprocessor on the integrated circuit (15) analyzes the incoming data and Nanoparticles are transmitted in real-time via the communication module located on it. instantaneous nanoparticles characterized by their transmission to the guidance system. It is a routing system. 30

Images