MECHANICAL STATE-BASED THROMBECTOMY DEVICE

Abstract

The subject of the invention is the provision of a mechanical state-based thrombectomy device used in the field of endovascular mechanical thrombectomy, which locks the thrombus in a specific mechanical state instead of pulling it by force, compressing it with radial pressure, or holding it by adhesion. The device is structured with a multi-segment filament structure consisting of a distal filament cluster (1), a middle filament cluster (2), and a proximal filament cluster (3) arranged from distal to proximal, an asymmetric double carrier wire (4, 5) system, and axial overlap zones (6) located in the middle segment. The distal segment creates a fragment-confining geometry that prevents the thrombus from escaping in the distal direction, while the middle segment closes the axial freedom (DOF), establishing a mechanical lock and allowing the thrombus and the device to act as a single mechanical system. The proximal segment maintains mechanical stability by absorbing torsional and axial residual energy.Thanks to this holistic structure, the thrombus is removed from the vessel as a single piece without fragmentation or distal embolism.

Description

1 TARIFF MECHANICAL STATE-BASED THROMBECTOMY DEVICE Technical Area The subject of the invention is a device used in the field of endovascular mechanical thrombectomy that removes thrombi with a force of 5 Instead of pulling it out by applying pressure or compressing it with radial pressure, the thrombus is positioned in a specific mechanical state. It relates to a mechanical, state-based thrombectomy device that locks by passing a series of filaments through it. Thanks to its clusters, axial overlap areas, and asymmetric double carrier wire structure, the device removes thrombus. It forces them to act together as a single mechanical system. Thus, thanks to the device, the thrombus is made to behave like an elastic... By exhibiting pseudo-solid block behavior, it passes through the vessel without breaking apart and without forming a distal embolism. It is removed. State of the Art The most fundamental problems in current stent-retriever and aspiration-based thrombectomy systems. Fragmentation of the thrombus during removal, formation of distal embolism, radial compression of the vessel 15 risk of damage, sudden ruptures due to torsional energy accumulation, operator dependence and consequences The variability is such that the thrombus and the device behave like separate mechanical systems. Also, chronic or In thrombi with heterogeneous structures, existing systems frequently fail or require multiple passages. This requires. One of the methods in the current technique is stent-retriever (neurovascular clot). (capture / pull) operation occurs. Medtronic Solitaire™ X, Stryker Trevo NXT ProVue, Cerenovus 20 EMBOTRAP™ III is one example of these. Another method is direct aspiration thrombectomy. Penumbra ACE Reperfusion Catheters (aspiration): Example clinical study / application of ADAPT use. ACE catheters and the ADAPT approach are examples of these. Techniques with different combinations are also used. techniques such as aspiration, stent-retriever, and solumbra are being applied together. Neurovascular aspiration catheters / distal support catheters are also available. 25 Medtronic React™ aspiration catheters and Stryker AXS Catalyst distal access catheters are used. These are examples of catheters. Also, mechanical thrombectomy systems for pulmonary embolism (PE) are used in this field. It is used. The Inari FlowTriever system is an example of this. Additionally, mechanical techniques for venous thrombus / DVT are employed. Thrombectomy systems are also among the methods and devices used. Document number WO9904701A1, seen in the known state of the art, describes 30 thrombolytic materials. It describes the method and device for cleaning the lumens. It features a one-handed control operation. 2 A motor with this mechanism has a long wire attached to it, which allows it to be rotated. A catheter that wraps around a portion of the wire and a portion of the wire extending from the catheter will create a standing wave. While being rotated by the motor at a sufficient speed, it can be manually operated with one hand, independently of the wire. It includes a gripping mechanism that facilitates turning. According to document number US5370653A, which is seen in the current technique, the patient's vascular system has 5 vessels in one vessel. or to resolve a soft fibrous blockage, such as a newly formed thrombus, in a prosthetic implant. A thrombectomy method and device used are explained. Here, the aim is to separate the fibrin from the thrombus. It uses a rotating brush for mixing. The brush has a drive motor assembly attached to its proximal end. soft, flexible bristles extending outwards from the distal end of a long, flexible, rotatable drive shaft This occurs. The brush is passed through the entry lumen and exited through the distal opening, and the brush bristles come into contact with the thrombus. 10 It is done. The previous technique described in document number US10743907B2 involves removing a thrombus from the body lumen. A thrombectomy device used for this purpose is described. It has longitudinal sections with distal and proximal portions. from a catheter element, with a constricted orientation placed distal to the catheter element. an expanded, thrombus-blocking orientation between radially expanding thrombus blocking 15 It is a device consisting of a thrombus capture body. The thrombus capture body has an inwardly tapering anterior end. It is a cage. The extended control lever is functionally attached to the front end of the cage, and inside the cage there is a A thrombus-removing or thrombus-breaking mechanism has been implanted. The systems described in previous known technical documents are essentially either single units operating with rotational energy. wire / brush mechanisms (WO9904701A1; US5370653A) or radially expanding cage / block 20 It is based on stent-like capture systems with a flexible body structure (US10743907B2). Also used in the clinic are Solitaire™, Trevo™, EMBOTRAP™, ACE / ADAPT, React™, Catalyst™ and Systems like FlowTriever™ essentially work by either pushing the thrombus into the lumen through radial expansion or pulling it out. or it operates on the principle of suction by aspiration force. As can be seen, a single rotating brush, singular Instead of wire mesh or simply radially expanding lattice architecture, multiple 25s positioned sequentially along the axis A segmental structure composed of overlapping filament / element clusters encloses the thrombus as a single unit. There is no structure that surrounds and holds it in place as a block. Furthermore, the thrombus and the device are two separate mechanical structures. preventing the system from behaving as it should, fragmentation during withdrawal and distal embolism formation. a structure that offers a continuous contact and gripping geometry aimed at structural reduction It is not available. For these reasons, the need for research and development work in this field has arisen. 30 3 Purpose of the Invention The aim of the invention is to create multiple filament / element clusters that are sequential and overlapping along the axis. The thrombus is formed thanks to a segmental mechanical structure that works in conjunction with a carrier core wire. The goal is to ensure its withdrawal as a single piece, while environmentally grasping it and preserving its integrity. Thus, the risk of fragmentation and distal embolism during withdrawal is reduced, and the thrombus is minimized. The goal is to prevent the device from behaving like separate mechanical systems. The aim of the invention is to create multiple filament / element clusters positioned sequentially along the axis. The goal is to achieve circumferential encapsulation of the thrombus through the formation of a segmental structure. The aim of the invention is to create a filament containing an overlapping region where the filaments are positioned to overlap each other. The continuity between segments is achieved through clustering. 10 The aim of the invention is to achieve traction by creating continuous contact between multiple filament clusters around the thrombus. The goal is to ensure the integrity of the thrombus is preserved during this process. The aim of the invention is to fragment the thrombus during detachment by means of a sequential and overlapping element arrangement. The goal is to prevent this from happening. The aim of the invention is to mechanically grip filament clusters around the thrombus with a geometry that distals 15 The goal is to reduce the risk of embolism formation. The aim of the invention is to create a carrier shaft / core wire structure extending along the device housing and filament clusters. The goal is to ensure they move together and in a controlled manner. The aim of the invention is to achieve thrombosis through mechanical integration between the core wire and the filament clusters. This ensures that the device is not treated as separate mechanical systems. 20 The aim of the invention is to create a multi-element structure that limits and distributes torsional energy accumulation into a segmental structure. The aim is to reduce the risk of sudden rupture through this configuration. The aim of the invention is to create a filament that surrounds the thrombus circumferentially, not relying solely on radial compression. It is the demonstration of mechanical cognition through sets. The aim of the invention is to create a device that does not rely solely on aspiration, but mechanically holds and collects the thrombus together with 25 The goal is to obtain an extraction mechanism that carries out the extraction. The aim of the invention is to achieve increased contact between multiple filament clusters in chronic or heterogeneous thrombi. The goal is to increase efficiency thanks to its surface area. 4 The aim of the invention is to provide continuous gripping along the thrombus with an axial overlap structure for multiple passages. The goal is to ensure that the need is reduced. The invention aims to enable the operator to use segmentally and axially aligned filament clusters. The goal is to reduce addiction. The aim of the invention is to prevent thrombus from distalizing into embolism by creating a continuous gripping zone in the distal end region. The goal is to ensure its withdrawal without any reason. To achieve the above objectives, the subject of this invention is endovascular mechanical thrombectomy. used in procedures to remove thrombus from within the blood vessel, active thrombus-pulling force. and / or axial freedom by converting to a mechanical state without creating radial compression and / or adhesion. 10 that enables its closure, thus allowing the thrombus to move as a whole with a structural locking mechanism. Mechanical thrombectomy device; prevention of thrombus escape in the distal direction and microfragment formation. The fragment-trapping distal filament cluster, which prevents the thrombus from making primary contact, and the central filament cluster that enables the mechanical lock to be created by closing the axial freedom, dissipation of torsional and axial residual energy that may form within the thrombus and mechanical The proximal filament cluster, which includes a gradual rigidity transition ensuring stability, withstands an axial load of 15 The primary carrier wire, which enables the transmission of torsional energy to the system in a central and controlled manner, It has an asymmetrical structure that allows for damping within the system and the creation of a torsional dead zone. The secondary carrier wire enables the closing of the axial freedom (DOF) and the mechanical lock to operate without generating force. The axial overlap zone that enables its formation allows for volumetric and circumferential contact with the thrombus. A filament that provides, does not generate force and prevents radial compression from occurring, is inserted into the thrombus 20 It includes a distal end element that allows progression without causing traumatic effects. Filaments are flexible metal contact elements, with a central filament cluster containing axial overlap regions. It includes features that enable axial load transfer and torsional energy dissipation. It contains an asymmetric double-wire primary and secondary carrier wire. It aims to reduce axial DOF to zero and prevent thrombosis. It includes a mechanical locking core that allows the device to be clamped together as a single mechanical system. Traction 25 structural carrier and connecting element that enables the transmission of movement to active filament clusters It includes a proximal carrier shaft. It includes a soft and non-cutting distal end element. Nickel titanium. an elastic contact element made of alloy (NiTi) that makes direct contact with the thrombus and does not generate force. It contains filaments. Explanation of Invention Methods Figure 1 - View of the Thrombectomy Device Filament Cluster Group Figure 2 - Thrombectomy Device - Thrombus Placement and Filament Retention Appearance in the Vessel Figure 3 - Detailed Cross-Sectional View of Thrombectomy Device Filament Cluster Group Reference Numbers: 1. Distal Filament Cluster 5 2. Medium Filament Cluster 3. Proximal Filament Cluster 4. Primary Carrier Wire 5. Secondary Carrier Wire 6. Axial Overlap Region 10 7. Filament Detailed Description of the Invention The device described in the invention contains a group of filament clusters at its distal end. These are shown in Figure 1. 15 as distal filament cluster (1), middle filament cluster (2) and proximal filament cluster (3) It is separated. It includes the primary and secondary carrier wire (4,5) shown in Figure – 3, as well as axial overlap. region (6) includes distal filament cluster (1), middle filament cluster (2) and proximal filament cluster (3) It consists of flexible metal filaments (7). Distal filament clusters (1) in the distal direction of the thrombus The fragment trap geometry prevents escape. Filament clusters in the middle segment (2) This is the mechanical locking zone where the main contact with the thrombus is established and axial freedom is closed. Axial 20 Overlap zones (6) close the DOF, preventing device-independent movement of the thrombus. Primary While the carrier wire (4) transmits the axial load from the center and in a controlled manner, the secondary carrier wire (5) transmits the torsional load. It absorbs energy. The Pt–Ir region forms the basal load reference of the system. The proximal segment (3) now It maintains mechanical stability by absorbing energy. NiTi filaments (7) establish volumetric contact with the thrombus. However, it does not produce radial force. Axial overlap regions (6) create the DOF=0 condition, thus locking the mechanical lock 25 It establishes an asymmetric double carrier wire (4, 5) structure that creates a torsional dead zone, allowing for a sudden energy release. obstacles. Gap=0 continuity eliminates sudden stress peaks. 360° homogeneous filament (7) distribution It consolidates the thrombus circumferentially. Flexible filament (7) structure that does not produce radial compression in the vessel It reduces damage. Disabling adhesion eliminates unpredictable attachment. This holistic approach... 6 Thanks to this structure, the thrombus and the device act as a single mechanical system, and the thrombus is fragmented. It is removed as an elastic pseudo-solid block without passing through. The end element (8) at the distal end of the device It is the part that first comes into contact with the thrombus. This element (8) has a soft and non-cutting structure. Its function is, The goal is to ensure the device enters the thrombus without causing traumatic effects during its advancement. Distal end element (8) does not produce an active force and only provides atraumatic initiation. From distal to proximal 5 Correctly arranged successive filament clusters (1, 2, 3) form the active thrombus contact structure of the device. This Clusters (1, 2, 3) are arranged to make volumetric and circumferential contact with the thrombus. Each cluster (1, 2, 3) consists of numerous flexible metal filaments (7). These filaments (7) are NiTi based and with thrombus They are elastic contact elements that make direct contact but do not generate force. Filaments (7) radial compression It is structured in such a way as to create contact that is volumetric and environmental. 10 The invention describes a multi-segment, gap=0 continuity, axial device designed to solve known problems in the field. It has a configuration that closes off freedom in the mid-segment and dampens torsional energy. Distal segment negative outer diameter taper and fragment confining geometry with distal escape geometry This has been made impossible. Axial overlap regions located in the mid-segment generate axial force without causing axial movement. It creates a mechanical lock by reducing DOF to zero. The asymmetrical dual core-wire structure provides a torsional dead zone of 15. By forming, it prevents the transmission of torsional energy to the distal segment. NiTi filaments (7) radial compression It is designed with a flexibility that will not produce adhesion, completely eliminating the possibility of thrombosis. It is not held by force; instead, it is transformed into a deterministic mechanical state, creating a single system behavior. The invention... Thanks to this method, the thrombus can be removed without applying force, forming adhesions, and without radial compression. The goal is to ensure the safe removal of the thrombus from the blood vessel without causing further damage. (Figure – 2) Axial thrombus 20 a confined, torsionally damped and elastic pseudo-solid behavior The aim is to put the patient into a mechanical state and maintain this state throughout the traction process. Also, acute ischemic... Cerebral artery occlusions, peripheral arterial occlusions, and venous disorders, primarily stroke. In thromboses, to provide high recanalization in a single pass and structurally reduce the risk of distal embolism. It has been ensured that it is eliminated. 25 The distal filament cluster (1) forms the distal segment. This segment consists only of NiTi filaments (7). Its function is to prevent the thrombus from escaping distally and to prevent microfragmentation in this segment. A negative outer diameter (OD) taper is applied. There is no axial overlap region (6) in this area. Distal segment, The fragment forms a confining shape, structurally preventing distal embolism. The middle filament cluster (2), mid It forms the segment and mechanical lock core. This region is where the main contact with the thrombus is established and the mechanical 30 This is the region where the lock occurs. In addition to NiTi filaments (7) in the mid segment, there is a basal Pt–Ir load reference region. It is located. The load enters the system via this reference. In this segment, the clusters of (7) within itself Axial overlap regions (6) are thus formed in the transition zones between them. Axial Overlap regions are found only at the transitions of the (6) middle filament cluster (2) region. This overlap 7 Not for generating force, but to ensure continuity and close the axial freedom (DOF). It is arranged. A mechanical lock is established in the middle segment so that the axial DOF = 0. This region is thrombus. This enables the device to behave as a single mechanical system. Proximal filament cluster (3), proximal It forms a segment. This section contains a gradual rigidity transition. Its function is to detect potential problems that may occur in the system. to absorb torsional and axial residual energy and isolate the load from the active thrombus contact area 5 This segment does not directly create a mechanical lock; it provides energy management. The central part of the device. The primary carrier wire (4) extending along the axis transmits the axial load to the system from the center and in a controlled manner. It enables the transfer of load. This wire has a thicker structure and is the primary load-bearing element. The Pt- in the middle segment It forms the load reference by working together with the Ir region. The secondary carrier wire (5) is different from the primary wire (4). It has mechanical properties and an asymmetrical structure. It has a finer structure and the torsional energy of the system is 10. This allows it to be damped inside. The two carrier strings (4, 5) have different pitch values. This asymmetry It prevents the formation of torsional resonance and creates a torsional dead zone. Thus Torsional energy is not transmitted to the distal segment. Flexible metal filaments (7), each filament cluster (1, 2, 3) These are the elements that come into direct contact with the thrombus. These filaments (7) have volumetric and circumferential contact with the thrombus. It does not generate force, does not create radial compression, and does not adhere by adhesion. The thrombus has a specific 15 It provides a contact surface for mechanical loading. The load reference filament region is located in the middle segment. It receives and ensures that the load is initiated from the center and transferred without slippage. This region contains Pt–Ir alloy. and forms the basal load reference of the system. It does not extend to the distal segment and does not come into contact with the vessel wall. Axial overlap region (6), transition regions between filament clusters (1, 2, 3) in the middle segment It is located there. Its function is to close the axial freedom and enable the mechanical lock to form. This overlap is 20 It does not generate force; it is structured solely for the purpose of geometric continuity and DOF closure. Proximal The carrier shaft is the supporting structure that connects the active filament sets to the control system. The traction movement occurs via this shaft. It is transmitted through. It is a structural carrier and connecting element. All segments of the device (1, 2, 3) gap = 0 It is regulated according to the principle of continuity. The distal segment prevents fragment escape, the mid (middle) segment... It forms a mechanical lock, the proximal segment absorbs energy. Double wire (4, 5) structure axial load transfer 25 and provides torsion damping. Filament clusters (1, 2, 3) establish volumetric contact with the thrombus. Axial The overlapping areas (6) close the freedom. The whole structure is like a single mechanical system with the thrombus and the device. It is configured in a way that will cause it to behave in a certain way. This invention represents a break from existing force- and adhesion-based approaches in the field of endovascular mechanical thrombectomy. It offers a mechanical, state-based platform that fundamentally differs from existing approaches. The invention's 30 The basic approach is to draw the thrombus out, compress it, or superficially trap it with the device. instead, the thrombus is placed in a specific mechanical state, and this state is deterministic. The device is designed to lock the thrombus together and transport it as a single piece without disrupting its position. 8 It does not generate active force on the thrombus; it analyzes the behavior of the thrombus geometrically, structurally, and temporally. It is determined through constraints. The mechanical condition targeted within the scope of the invention is one in which the axial freedom is absolute in the middle segment. closure (DOF = 0), damping of torsional micro-movements within a certain limit, and thrombus The device behaves not as separate but as a single mechanical system, defined by its parameters. These 5 When the mechanical condition is achieved, the thrombus is an elastic, centrally located, and pseudo-solid structure with its internal structure preserved. It acts like a block. The device that is the subject of the invention is a multi-segmented device extending from distal to proximal and It has a continuous structure. The device consists of an active thrombus contact area and a wire system providing load reference. It consists of torsion and energy management structures and a proximal energy absorbing region. The entire structure has a gap of 0. It exhibits continuity according to its principle and does not contain sudden geometric or rigidity breaks. The device, 10 It includes an asymmetric double wire (4, 5) structure to provide uniaxial load transmission. This structure is the primary It consists of carrier wire and secondary torsion damping wire (4, 5). The two wires in question (4, 5) They are not of equal thickness and have different pitch values. This asymmetry allows for torsional resonance. This prevents the formation of micro-torsions, dampens them within the system, and torsional energy is transferred distal. It is not transmitted to the region. The absolute load reference of the system is 15 Pt-Ir alloy used on wire (4, 5). It forms a structure that does not extend to the distal segment, is not located peripherally, and does not come into contact with the vessel wall. It does not. The device is structurally divided into three main regions: the distal segment, the middle segment, and the proximal segment. It is separated. The distal segment consists of distal filament clusters (1) and consists only of NiTi filaments. (7) consists of. It prevents distal fragment escape and negative outer diameter taper is applied, micro-flow-20 The area contains killer surface structures. Axial overlap is absolutely forbidden in this region. Thanks to this structure... The thrombus is unable to escape distally, and fragmentation is geometrically prevented. (Middle) The segment is the region where the core functions of the invention are realized. This region contains NiTi and partial Pt–Ir. The filaments (7) are used together to create a single and direct contact area with the thrombus and the load It enters the system via the basal Pt-Ir. Axial freedom closure in the middle segment is achieved by filament 25. This is achieved by the axial overlap created in the transitions of the clusters (2). These overlapping regions (6) It is gradient-free, does not generate force, and is used solely to ensure gap = 0 and DOF = 0. Furthermore, axial phasing is achieved thanks to the filament geometry and segment arrangement, and the load The thrombus is transferred gradually over time, and no sudden stress peaks occur. Proximal This segment is present to absorb any residual energy that may occur in the system. The rigidity in this region is 30 degrees. There is a passage, torsional and axial energy is damped, and the load is transferred from the active thrombus contact area. It is being isolated. 9 The study of the invention is two-phased. In Phase 1, the device is placed inside the thrombus, but The lock is not engaged. Minimum time is provided during this phase, symmetrical contact occurs, and an error occurs. The configurations are not stabilized. In Phase 2, a mechanical lock is installed. Lock However, this occurs only when the active conditions of axial DOF = 0 and torsional dead-zone are met. These conditions are: Without this, no stabilization becomes permanent. In mid-segment NiTi filaments, 5 (7) There is only Ca²⁺ functionality that is active during Phase-2. This functionality is chemical It does not form adhesion, it is only effective in filament-filament intercontact zones and filament (7) intercontact It shows a gradient from the basal to the free end along its axis. In the distal segment, Pt–Ir Ca²⁺ is absolutely absent from their surfaces and in vascular contact. Throughout the mid-segment. The filaments exhibit a 360° angular homogeneous distribution and anti-phase synchronization with micro-angular offsets. 10 This structure provides continuity of peripheral contact, ensuring that the thrombus remains as a single, peripherally intact unit. It enables the device to behave in a certain way. The device is only used with a single, continuous, and monotonous pull. Push, No stop-start or free rotation movements are applied. This mode of use ensures the mechanical condition. It prevents deterioration. Filaments (7) 360° angular homogeneous distribution along the middle segment. It demonstrates and provides anti-phase synchronization with micro-angular offsets. This structure provides environmental contact 15 It creates continuity and ensures that the thrombus behaves as a single, peripherally intact unit. The invention is a mechanical state-based thrombectomy device, primarily for endovascular mechanical thrombectomy. applications including the treatment of acute ischemic stroke and vascular occlusions without the need for surgery It is used in mechanical treatment via intravascular means. The device is particularly suitable for large vessels. Acute 20 aimed at removing the thrombus in one piece and without forming a distal embolus in vascular occlusions (LVO). It can be applied in the treatment of ischemic stroke. It is also used in ICA-T, M1, M2 and similar intracranial strokes. In the treatment of thrombotic occlusions in arteries, endovascular treatment of cerebral artery occlusions. It finds application in the treatment of renal, mesenteric, splenic and extremity lesions. In peripheral and visceral arterial occlusions occurring in the arteries, thrombi develop endovascularly. It can be applied in removal via this method. 25 The device is used in the treatment of venous thrombi, particularly in deep vein thrombosis (DVT) and pre-pulmonary embolism. It can be used for the mechanical removal of venous thrombi. Chronic and subacute thrombi. in their interventions, thrombi that have become organized over time, with high cohesion or heterogeneous structure It is applicable for the transport of fragmentation-free materials. Soft, brittle, or layered fibrin-erythrocytes. In the treatment of thrombi that are structural and carry a high risk of fragmentation without causing distal emboli, 30 It has a wide range of uses. Furthermore, in clinical scenarios where reducing operator dependency is critical, the difference in experience in centers where it significantly affects results, deterministic and repeatable performance is required. It can be used in applications where force and radial pressure are limited, and where there is damage to the vessel wall. It may be preferred in anatomies where the risk of dissection or perforation is high. Currently available. when stent-retriever or aspiration techniques are insufficient, complete recanalization cannot be achieved, or It can also be applied in situations requiring multiple passes. In addition, recanalization can be done in a single pass. (First Pass Effect) focused, where minimizing procedure time and distal embolism risk is critical. 5 It has applications in treatments. The device also allows the operator to use it thanks to its state-locked IFU. In training, simulation, and standardized clinical protocol applications where variation is reduced It is available for use.

Claims

11 REQUESTS 1. In endovascular mechanical thrombectomy procedures, the thrombus inside the vessel used in the removal of the thrombus by active pulling force, and / or radial compression and / or Closing off axial freedom by converting to a mechanical state without forming adhesions. 5 that provides, thus enabling the thrombus to move as a whole with a structural locking mechanism. It is a mechanical thrombectomy device; its features include:  Distal escape of the thrombus and formation of microfragments Fragment-trapping distal filament cluster (1), which enables blocking.  Establishing main contact with the thrombus and closing axial freedom to enable mechanical The middle filament cluster (2) that enables the lock to be formed, 10  Dissipation of torsional and axial residual energy that may form within the thrombus and includes a gradual rigidity transition that ensures the preservation of mechanical stability. proximal filament cluster (3),  Enables the axial load to be transmitted to the system from the center and in a controlled manner. primary carrier wire (4), 15  Dissipation of torsional energy within the system and torsional dead zone Secondary carrier wire with asymmetric structure that enables its creation (5),  Closing the axial freedom (DOF) and the mechanical lock without generating force Axial overlap region (6) which enables its creation,  A non-force-generating 20 that enables volumetric and circumferential contact with the thrombus. and filament (7) which prevents radial compression from being created.  The distal end allows the thrombus to advance without causing traumatic effects. element (8), It includes.

2. A mechanical thrombectomy device conforming to Claim 1, whose feature is that the aforementioned filaments (7) 25 They are flexible metal contact elements.

3. A mechanical thrombectomy device that meets any of the above requirements, and whose features include: The reason is that the middle filament cluster (2) contains the axial overlap regions (6).

4. A mechanical thrombectomy device that meets any of the above requirements, and whose features include: 30 that enables axial load transfer and torsional energy dissipation. It contains an asymmetric double-strand primary and secondary carrier wire (4, 5). 12 5. A mechanical thrombectomy device that meets any of the above requirements, and whose features include: The goal is to reduce axial DOF to zero and to treat the thrombus and the device as a single mechanical system. It contains a mechanical locking core that enables it to interlock.

6. A mechanical thrombectomy device that meets any of the above requirements, and whose feature is traction. structural carrier and connector 5 that enables the transmission of movement to the active filament clusters (1, 2, 3). It includes a proximal carrier shaft containing the element.

7. A mechanical thrombectomy device that meets any of the above requirements, and whose features include: It contains a soft and non-cutting distal end element (8).

8. Nickel titanium alloy (NiTi) structure, in direct contact with the thrombus, non-force generating. It contains filaments (7) which are elastic contact elements. 10

Images