A DUAL-PHASE SYNCHRONIZED MICRO-NEBULIZATION METHOD INTEGRATED BIOLOGICAL ALLERGEN ELIMINATION AND A DERMATOLOGICAL THERAPY SYSTEM WORKING IN ACCORDANCE WITH THIS METHOD.

Abstract

The invention relates to a method for improving indoor air quality, providing biological surface decontamination, and integrative dermatological care by co-dosing inactive probiotic spores with molecular triggers to activate them, and a system that operates in accordance with this method.

Description

BY DUAL-PHASE SYNCHRONIZED MICRO-NEBULIZATION METHOD INTEGRATED BIOLOGICAL ALLERGEN ELIMINATION METHOD AND A dermatological therapy that works according to this method. SYSTEM Technical Area The invention relates to improving indoor air quality and biological surfaces. inactive for cleansing and integrated dermatological care probiotic spores are dosed into the environment together with molecular triggers. a method by which probiotic spores are activated and suitable for this method It relates to a working system. The invention, more specifically, involves the application of inactive probiotic spores (Bacillus spp). synchronized to the environment with immediate molecular triggers (L-Alanine, L-Asparagine, etc.) by dosing and activating probiotic spores, resulting in high germination efficiency. It relates to the activation method. This process involves two separate devices, such as ultrasonic, etc. by initiating the germination process in the air and continuing it on the ground, and the process It enables the process to be accelerated by reducing it from hours and days to minutes. Previous Technique In current applications, probiotic spores are used to improve air quality and biological processes. It is used to provide surface purification. Probiotic spores, a through sprays or air conditioning devices or systems, into the environment They are sprayed. However, these probiotic spores are in an inactive state and this Probiotic spores are activated by organic compounds and moisture found on surfaces. They are. 1 Previous techniques involved liquid suspensions containing probiotic spores or their derivatives. Stabilized formulas in the same bottle as prebiotics for ambient or climate control or it is sprayed into the ventilation duct using devices or spray bottles. Many companies around the world have different dosage practices. The reason is that probiotic bacteria are dormant, so they wake up when they land on the surface. and they need nutrients and moisture to start producing enzymes. Their ability to hear. All sports remain dormant if they cannot access this nutrient and moisture. Since this will continue, companies are spraying as many sports into the environment as possible. tends to For this purpose, probiotic spores are combined with molecular triggers (synergistic activators). When placed in the same container before dosing, it extends the product's shelf life. Uncontrolled activation occurs in probiotic spores. This This situation leads to the premature death of many probiotic spores before they are even dosed into the environment. It opens. “Germination of spores of Bacillus species: what we know and do not know” An explanation of this problem is given in the article titled [article title] (Peter Setlow, 2014). It is receiving. Another problem is that probiotic spores cannot be produced without an activator. In the dosage, the probiotic spores are not activated to a sufficient level. Similarly Even when insufficient activator is used, probiotic spores still do not form. The problem is that it does not activate at the desired level. Another problem is the accumulation of moisture and dust in central ventilation ducts. This leads to the growth of pathogens. Traditional systems used in these areas... Disinfectants, however, leave behind residues that are harmful to human health. Another problem is with all manual or device-based probiotic systems. This is the initiation of the germination and sprouting process of probiotic spores on the surface. 2 This is so that the probiotic spores fall to the ground after being sprayed into the air. a few hours and even a few hours for the process to start and occur on the surface. It takes days. is required. In the patent document numbered EP3686266A1, which is included in the prior art, the most spores of a small, non-pathogenic Bacillus genus species and a prebiotic component The text refers to a surface treatment compound containing the following: to remove unwanted, harmful or pathogenic microorganisms from surfaces It is used for grafting onto these surfaces for this purpose. In the patent document numbered EP3685669A1, which is included in the prior art The text describes a composition for the decontamination and inoculation of surfaces. The compound in question is an antimicrobial agent and stabilized bacteria. It consists of a mixture. In the patent document numbered EP3286291B1, which is included in the prior art. probiotic bacteria in a base solution that has a disinfecting and / or hygienic effect and formed by mixing bacteriophage elements, used for cleaning and disinfection. and the product used for hygiene is mentioned. Here, probiotics are discussed. The bacteria are preferably Bacillus subtilis, Bacillus megaterium, and Bacillus pumilus. They are of the genus, and bacteriophage elements are alternative or combinational. in case of Caudavirales, Microviridae, Leviviridae, inoviridae, Tactiviridae, It includes bacteriophages from the Corticoviridae family. In the patent document numbered EP2430138A1, which is included in the prior art. Specifically, the breakdown and / or removal of inorganic stains and / or residues. for hard surfaces, especially the ceramic surfaces inside and around toilets and urinals It is mentioned that it is used for cleaning and / or polishing. 3 In the patent document numbered GB2484134A, which is included in the prior art, the most a small amount of Class 1 Bacillus bacteria - a cleaning compound, - one or more This refers to an aqueous composition containing a surfactant. A cleaning compound. preferably d-limonene. Bacillus spores preferably Bacillus circulans, Bacillus It is either Bacillus megaterium or Bacillus sphaericus. Additionally, there is at least one Class 1 Bacillus. a bacterial spore, a cleaning compound, and one or more surfactants a surface cleaning method that involves applying a watery solution to a surface It has been explained. When the existing systems and methods in technology are examined, as mentioned above... a more effective method and system for resolving technical problems The need for its implementation has arisen. Purposes and Brief Description of the Invention The aim of this invention is to synergize probiotic spores with molecular triggers (synergistic (activator) is dosed into the environment separately, and thus the probiotic is pre-dosed It is the implementation of a method in which the uncontrolled stimulation of the body is prevented through sports. Another aim of this invention is to ensure that probiotic spores are activated to a sufficient level. It is the implementation of a method that ensures this. Another aim of this invention is to allow probiotic spores to remain active for a much shorter period after dosing. It is the implementation of a method that is activated within a certain period of time. Another aim of this invention is to stabilize, moisturize and strengthen the human skin barrier. It is the implementation of a method that has a restorative effect. In the method using a dual-phase activator system, Bacillus spores Germination efficiency is affected by molecular triggers (L-Alanine, L-Asparagine, Glucose, Fructose and KCl (Potassium Chloride) are increased. This helps to reduce mite allergens and mold. While their structures are being enzymatically destroyed; simultaneously, those suspended in the air and 4 micro-droplets landing on the surface (Hyaluronic Acid, Aloe Vera, Provitamin B5) through which it stabilizes, moisturizes and repairs the human skin barrier It forms a "Dual-Phase Atmospheric Maintenance Shield". Molecular triggers. The probiotic spores, released into the air in a synchronized manner, rapidly initiate the germination process. It causes irritation. Spores that do not meet triggers in the air, however, fall to the surface. then with triggers in the continuously sprayed activator solution They meet on surfaces, awaken, and begin producing enzymes. Eventually, hours and... A process that used to take days is reduced to minutes with this application. Detailed Description of the Invention The invention concerns the method - B. subtilis, B. licheniformis, B. megaterium, B. pumilus, B. Amyloliquefaciens contains at least one of the probiotic spore types, in ultra-low temperatures. Hyaluronic Acid, Aloe Vera 200x, Provitamin B5 (Panthenol) and volumetric A primary mixture containing 0.5% - 10% propylene glycol is introduced into a medium using a primary device. dosage by, - L-Alanine, L-Asparagine, Glucose, Fructose, KCl molecular triggers at least one of them and the second mixture containing 0.5 - 10% by volume of propylene glycol dosing into the same environment by a second device It includes the steps. In the method described in the invention, two separate phases (mixtures) are mixed in two separate units with a diameter of 1-5 μm. It is being sprayed. The first mixture includes B. subtilis, B. licheniformis, B. megaterium, B. pumilus, B. Amyloliquefaciens contains at least one probiotic spore or a different Bacillus strain. It contains ultra-low hyaluronic acid (HA) in its first component. It increases bacterial surface adhesion while providing hydration in the deeper layers of the skin. It provides. The first ingredient, Aloe Vera 200x, provides a prebiotic protective shield against bacteria. It exhibits an anti-inflammatory effect on the skin while forming. The first mixture contains provitamin B5 (Panthenol), a bacterial fatty acid. It supports the metabolism (Coenzyme-A) and in human skin It accelerates epithelialization. Propylene glycol, included in the first mixture, constitutes 0.5% - 10.0% by volume of the first mixture. It is among them. Propylene glycol protects the mesh nozzles and The droplet ensures the stability of the MMAD active ingredient in the air. It prevents the spores from drying out and increases the activity of the germination process. It protects. Here, strains that have passed into vegetative form neutralize Der p 1 allergens in mite feces. They secrete hydrolyzing proteases and inhibit mold growth with iturin / surfactant. It suppresses. The second mixture used in the method described in the invention stimulates the spores. The second mixture contains L-Alanine, L-Asparagine, Glucose, Fructose, and KCl molecules. It contains at least one of its triggers. This combination (AGFK), sport By synchronously stimulating its receptors (GerA / B / K), the germination rate is increased to over 90%. It extracts. The propylene glycol in the second mixture constitutes 0.5% - 10.0% by volume of the first mixture. It is among them. Propylene glycol protects the mesh nozzles and The droplet ensures the stability of the MMAD active ingredient in the air. It prevents the spores from drying out and increases the activity of the germination process. It protects. The key point of the method is that the two phases are separated into individual units with diameters of 1-5 μm. The application is by spraying. The application involves spore droplets and humectants with holuronic acid. 6 aloe vera and vitamin B5 with activator drops (L-Alanine, L-Asparagine, Glucose, fructose, and KCl undergo "fresh activation" by colliding in the air or on a surface. It is designed to be initiated. The method involves connecting the fresh air inlet line of central air conditioning (HVAC) units or This positioning can be applied to the starting point of the main delivery channel. This micro- By ensuring that the droplets are delivered in sync with the air flow rate; (i) (ii) elimination of mold spores in the ducts, (ii) central control of the entire enclosed area (iii) feeding with dermatological matrix and (i) biologically extended filter lifetimes It ensures its extension. The combination of components that forms the basis of this method is a random combination. No, it is the result of an interdependent technical necessity: 1. Included in the device: Dermatological agents contained in the activator formula. (Hyaluronic Acid and Aloe Vera) are beneficial not only for human skin but also for vegetative purposes. It acts as an "exocellular protective shield" for the sensitive Bacillus cells that transition to the new form. It is seen. These polymers, present in micro-droplets in aerosol form, affect the bacteria. by significantly increasing the survival rate against dehydration stress, It physically guarantees the biological effectiveness of the system. The cosmetic active ingredients used in the method after probiotic germination It stimulates the rate of biofilm formation and mechanically enhances surface adhesion. It is predicted that this will support "allergen management" and "skin therapy". their claims are not independent of each other, but rather a synergistic ecosystem. It requires evaluation. 7

Claims

1. The invention relates to the improvement of indoor air quality and biological surfaces. Active for cleansing and integrated dermatological care. non-probiotic spores are released into the environment along with molecular triggers. a method in which probiotic spores are activated by administering doses related to, - B. subtilis, B. licheniformis, B. megaterium, B. pumilus, B. Amyloliquefaciens contains at least one of the probiotic spore types, in ultra-low temperatures. Hyaluronic Acid, Aloe Vera 200x, Provitamin B5 (Panthenol) and volumetric A primary mixture containing 0.5% - 10% propylene glycol is introduced into a medium using a primary device. dosage by, - L-Alanine, L-Asparagine, Glucose, Fructose, KCl molecular triggers at least one of them and the second mixture containing 0.5 - 10% by volume of propylene glycol dosing into the same environment by a second device It is characterized by including its steps.

2. The invention is a method as described in claim 1, where two separate phases (mixtures) are mixed in two separate ways. It is characterized by spraying with a diameter of 1-5 μm using a unit. 8