AN AGENT CONTAINING PINE BUG (Thaumetopea Pityocampa) EXTRACT FOR USE IN THE TREATMENT OF PAPILLOMES AND OTHER PROLIFERATIVE SKIN LESIONS IN ANIMALS.
Patent Information
- Authority / Receiving Office
- TR · TR
- Patent Type
- Applications
- Current Assignee / Owner
- SELÇUK ÜNİVERSİTESİREKTÖRLÜĞÜ
- Filing Date
- 2026-06-01
- Publication Date
- 2026-06-22
Abstract
Description
Papillomas and other proliferative skin lesions in animals. PINE BUG (Thaumetopea) FOR USE IN TREATMENT Agent containing Pityocampa extract TECHNICAL FIELD The invention addresses dermatological conditions seen in animals within the field of veterinary medicine. The invention relates to a product aimed at treating diseases. In this context, the invention concerns the pine processionary moth. Active ingredients derived from the extract of the caterpillar (Thaumetopoea pityocampa), When used in ointment formulations, it is particularly beneficial for ruminants. In the treatment of papillomas and other proliferative skin lesions seen in animals, or It relates to a veterinary dermatological product that can be applied in its elimination. PREVIOUS TECHNIQUE Papillomas can be found in many animal species, especially ruminants. These are proliferative skin lesions of viral origin. These lesions pose clinical risks to animal health. In addition to causing discomfort, the location of the lesions, the extent of their spread, and animal welfare and productivity due to the risk of developing secondary infections. It can have negative effects. Otovaccin applications and surgery are used in the treatment of papillomas. different approaches such as removal procedures, topical therapeutic ointments and lotions However, current treatment options do not provide adequate clinical results in every case. It does not provide a response; recurrence of lesions, prolonged treatment duration, application difficulty, cost, stress on the animal, and effectiveness in widespread lesions Disadvantages such as limitations may arise. In the current state of the art, papillomas and similar lesions found in animals topical products used for the treatment of proliferative skin diseases Its effectiveness depends, in most cases, on the type and extent of the lesion and the immune status of the animal. Surgical interventions are limited in their ability to remove local lesions. However, it can be used for numerous or widespread papillomas It does not offer a practical and adequate solution in the situations it is found in. Furthermore, surgery... The procedures require wound care, involve the risk of infection, and necessitate post-procedure follow-up. This is among the factors that limit its applicability in the field. Autovaccine While these applications are an option for generating an immune response, 1 preparation process, application protocol and predictable results in each animal. It has limitations in terms of not providing it. For the reasons mentioned above, papillomas and other proliferative skin lesions in animals suitable for topical application, for use in the field, in the treatment of diseases new, feasible alternatives or supportive treatments to existing options. compositions are needed. In this context, the pine processionary moth (*Thaumetopoea) extracts obtained from the extract of the caterpillar (pityocampa*) and extracts containing these extracts ointment formulations, papillomas and similar proliferative skin lesions in animals It has the potential to offer a new approach to the treatment of diseases. The subject approach involves applying plant-based or biologically derived active ingredients via topical carriers. by using them together, providing an alternative when existing methods are insufficient. It aims to create a treatment option. THE PURPOSE OF THE INVENTION The aim of the invention is to treat papillomas and other proliferative skin lesions found in animals. available treatment suitable for topical application that can be used in the treatment of lesions The goal is to develop a new product that can offer an alternative to existing approaches. In this context, pine... active ingredient obtained from the extract of the beetle larvae (Thaumetopoea pityocampa) By evaluating the components in different formulations, the aforementioned difficult-to-treat conditions contributing to the regression, control, or elimination of lesions The aim is to present a new approach. The agent will be produced using the extract obtained within the scope of the invention. Products in ointment form can treat papillomas and similar proliferative lesions in animals. can be applied in cases where existing methods are insufficient for treating skin diseases. The aim is to offer a supportive or alternative treatment option. Thus, limiting the spread of lesions, facilitating the treatment process, field increasing applicability in these conditions and contributing to the protection of animal welfare. The aim is to ensure this. DETAILED DESCRIPTION OF THE INVENTION The invention is derived from the caterpillar of the pine processionary moth (Thaumetopoea pityocampa) and It is related to an agent containing necrotic components found in the caterpillar's body. Pine The pine needle beetle can slow the growth or cause the death of various pine species. It is a species of butterfly that can feed on plants and wood. This creature, in nature... 2 In addition to the damage it causes, contact with the larvae is also dangerous due to the irritating hairs they carry during their larval stage. It can cause dermatological reactions in the living tissues it infects. In humans, the caterpillar's... Skin reactions can occur as a result of contact with irritating larval hairs. The caterpillar contains biologically active components that have effects on tissue. It shows. The effect of the pine processionary moth larva on tissue is also pronounced in animals. It is observed that in dogs, if the caterpillars come into contact with the mouth area, the mouth... severe mucosal inflammation, necrosis, and severe tissue damage in the mucosa and tongue tissue Losses can occur. This effect is due to thaumetopoein, which is present in the caterpillar's body. and other necrotic agents cause local tissue damage and necrosis in living tissues. It demonstrates that it can produce an effect. The agent described within the scope of the invention, this Based on biological effects, thaumetopoein is obtained from pine processionary moth larvae. It is an extract containing other necrotic substances found in the caterpillar's body. The agent described in this invention is used to treat papillomas and other proliferative skin lesions in animals. a veterinary dermatological active ingredient developed for application to lesions It is considered as such. Papillomas and other proliferative skin diseases, skin Since the lesions appear as abnormal tissue proliferation, the invention The basic principle of action of the agent used within this scope is obtained from the pine processionary moth larva. necrotic elements found in the extract on these proliferative tissues It creates a local necrotic effect. In this way, the papilloma or similar proliferative lesion... necrosis, reduction, or elimination in a way that contributes to the treatment process The aim is to remove it. The agent in question can be found either in extract form or in animal hides. an ointment to obtain a product suitable for controlled and local application. It can also be transformed into its final form. The ointment form is obtained from the pine processionary moth caterpillar. The extract obtained, which contains thaumetopoein and other necrotic substances, is used to treat papillomas. or allows topical application to areas with proliferative skin lesions. It is considered as a semi-rigid carrier form that provides active The extract is applied directly to the targeted lesion area, and the effect is primarily due to... It is intended to emerge in the field of application. When applying the product in ointment form, the active agent must come into contact with the lesion surface. contact is ensured. As a result of this contact, the substance found in the caterpillar extract is released. effect of necrotic elements on papilloma tissue or other proliferative lesion tissue It is expected that this will lead to the development of necrosis in the lesion tissue, thus reducing the lesion's size. 3 reduction in size or initiation of the elimination process for treatment The aim is to investigate the working principle of the invention, which involves the pine processionary moth larvae in living tissues. The necrotic effect it is known to produce is achieved with a controlled topical application. It is based on directing the approach towards proliferative skin lesions. In this context, the agent that is the subject of the invention is obtained from the pine processionary moth larva, Containing thaumetopoein and other necrotic substances found in the caterpillar's body, Used in animals for the treatment of papillomas and other proliferative skin diseases. It is defined as an extract designed for this purpose. This agent is available in extract form. It can be used to provide local and topical application to the lesion area. It can also be formulated in ointment form. The ointment form is designed to facilitate the application of the agent. retention in the region, contact with the lesion tissue, and necrotic effect a suitable veterinarian who enables it to be performed on the targeted proliferative tissue It forms a dermatological product formula. 4
Claims
1. Papillomas and other proliferative skin lesions seen in animals It is a veterinary dermatological agent suitable for use in treatment, and its characteristic feature is; Pine processionary moth (Thaumetopoea pityocampa) caterpillar containing thaumetopoein. It is characterized by containing an extract.
2. It is an agent according to claim 1, and its characteristic feature is that it is in ointment form.