DOUBLE-PHASE EXCHANGE MATERIAL-BASED PASSIVE VACCINE TRANSPORT SYSTEM PROVIDING PROTECTION AGAINST FREEZING RISK.

Abstract

The invention relates to a passive vaccine transport system used for transporting vaccines that provides protection against both overheating and freezing risks. The system comprises an outer transport body (1), a vaccine storage compartment (2) located inside the outer transport body (1), a PCM-A module (3) positioned at the top of the vaccine storage compartment (2), a PCM-B module (4) positioned at the bottom of the vaccine storage compartment (2), a thermal barrier (5) located between the PCM-A module (3), the PCM-B module (4) and the vaccine storage compartment (2), and a passive visual temperature indicator (6) on the outer transport body (1). The PCM-A module (3) and the PCM-B module (4) contain phase-change materials with different phase-change temperatures. The thermal barrier (5) forms a physical separator layer between the PCM modules and the vaccine storage compartment (2).The passive visual temperature display (6) allows for visual monitoring of the temperature status without the use of any electronic measuring device or external power source in the system.

Description

1 TARIFF DUAL PHASE EXCHANGE PROVIDING PROTECTION AGAINST FREEZING RISK. MATERIAL-BASED PASSIVE VACCINE TRANSPORT SYSTEM TECHNICAL AREA 5 The invention relates to the technical field of cold chain logistics, particularly concerning temperature. transportation of susceptible vaccines between production, storage and administration points transport systems for passively maintaining the temperature range during transport It relates to; more specifically, the invention is located inside the external carrying body. a vaccine storage compartment, 10 phase-change units with different phase-change temperatures material (PCM) modules, between the modules in question and the vaccine storage compartment Passive vaccine delivery system including thermal barrier and passive visual temperature indicator. It is related to the system. STATE OF THE ART 15 From the production facilities of temperature-sensitive biological products, especially vaccines. suitable temperature range from storage centers to application points Various cold chain transportation systems are used for this purpose. insulated transport boxes, cooling elements, phase change systems 20 materials (PCM), temperature monitoring devices and different insulation layers It is being used. In known technology, passive heating using phase-change materials. In controlled transport systems, maintaining a specific temperature range. Different layouts and insulation structures are proposed. In these systems, phase The 25 interchangeable materials are transported by placing them in different areas of the transport container. keeping the product within the target temperature range for a specific period of time that is intended. For example, in patent document number WO2017220953, the transport container within it, specific phase change materials with different phase change temperatures A passive temperature control system, arranged in an orderly fashion, is described. 30 The system enables the transportation of temperature-sensitive products within a specified temperature range. It offers a general transport container structure for this purpose. Patent document number WO2024229577 describes an insulated transport container. It uses a passive cooling unit together with phase change material. 2 and a transport system in which the product to be transported is positioned between these components. It is explained. In patent document number WO2022187699, different phase changes are mentioned. Using multiple phase-change materials with varying temperatures Packaging for transporting sensitive products within a specific temperature range 5 The system is explained. These systems, which are included in the current technology, mainly utilize high-temperature environments. Solutions for controlling the heat load generated by their temperatures It is present, and freezing may occur under low temperature conditions. It appears that there are limited structures in place to mitigate risk. Furthermore, 10 In some applications, cooling elements come into direct or indirect contact with the transported product. Depending on the contact, risks related to low temperatures may arise. Electronics In solutions using temperature monitoring systems, there is a dependence on the energy source. and additional costs may arise. Especially in field applications, rural areas. fully passive in regions and usage conditions where access to electricity is limited 15 There is a continuing need for employee transportation systems. For these reasons, existing in technology, passively operating conveying systems resistant to different temperature effects Improvements are needed in this regard. THE TECHNICAL PROBLEM WE AIM TO SOLVE IS 20. In current passive vaccine delivery systems, problems that may occur during transportation... considering both high ambient temperatures and low temperature conditions The limited availability of structures that provide this makes transporting temperature-sensitive vaccines challenging. This can lead to undesirable temperature changes. In addition, cooling elements used in current systems are suitable for vaccine storage. 25 positioned close to the compartment or in a location that could make direct contact Due to settlement patterns, there is a risk of freezing due to low temperatures. This is possible. In addition, electronic temperature monitoring systems require energy. the need for resources, especially field applications and access to electricity This creates a need for additional equipment in areas where it is not available. 30 The technical problem that is intended to be solved within this scope is the external transport hull. Around the vaccine storage compartment inside, different phase changes PCM modules with varying temperatures and the thermal components between them a barrier used in conjunction with, also includes a passive visual temperature indicator 3 a vaccine that maintains the completely passive structure of the system by creating a delivery system. It is about establishing a transportation system. A BRIEF DESCRIPTION OF THE INVENTION The invention relates to the production, storage and administration points of temperature-sensitive vaccines. Developed for use during transport between countries, to protect against the risk of freezing. a passive vaccine delivery system based on a dual-phase change material that provides protection It is related to the system; an outer transport body, located inside the outer transport body. a vaccine storage compartment, in different areas of the vaccine storage compartment The positioned PCM-A module and PCM-B module, with these modules, vaccine 10 a thermal barrier and a passive visual temperature gauge located between the storage compartments It includes the indicator. The system described in the invention consists of PCM modules with different phase transition temperatures. Passive transport is achieved through a structural arrangement that uses a thermal barrier in conjunction with the transport system. It creates a system that does not require any external power source, 15 It is structured in a way that allows it to be used. The invention, in particular, in field applications, mobile vaccination services, disaster areas and areas with limited access to electricity It is designed to be used in various fields. The advantages of the invention are listed below:  No electricity or batteries required. 20  Provides dual protection against freezing and overheating.  Improves cold chain safety.  It helps maintain vaccine efficacy.  Suitable for low-cost production.  Suitable for rural and field applications. 25  Temperature violations are easily detected thanks to the visual display. LIST OF FIGURES Figure 1. Dual phase change material-based passive vaccine delivery system, the subject of the invention. schematic view 30 The Definitions of the Numbers in the Figures 1. External transport body 2. Vaccine storage compartment 4 3. PCM-A module 4. PCM-B module 5. Thermal barrier 6. Passive visual temperature display DETAILED DESCRIPTION OF THE INVENTION The invention consists of an external transport body (1), a vaccine storage compartment (2), and a PCM-A module. (3), PCM-B module (4), thermal barrier (5) and passive visual temperature display (6) It consists of its components. The outer carriage body (1) forms the outer structure of the system and the other 10 It is the main carrier section in which the components are placed. The outer carrier body (1), vaccine storage compartment (2), PCM-A module (3), PCM-B module (4) and thermal barrier (5) It is designed to contain Passive visual temperature. The indicator (6) is visible to the user on the outer carrying body (1) It is located in a suitable area. 15 Vaccine storage compartment (2) is formed inside the outer transport body (1) This is the section where the vaccines to be transported are placed. Vaccine storage compartment (2), PCM-A module (3), PCM-B module (4) and thermal barrier (5) It is located within an enclosed settlement pattern. Thus, vaccine storage Compartment (2) constitutes the transport volume located at the center of the system. 20 PCM-A module (3) which controls the upper temperature limit, external carrying body (1) is located in relation to the vaccine storage compartment (2). The PCM-A module (3) is located on top of the vaccine storage compartment (2). PCM-A module (3), phase change material with different phase change temperatures It is located within the system as a module containing 25. PCM-B module (4) which controls the lower temperature limit, outer carrying body (1) It is located in relation to the vaccine storage compartment (2). Figure In the example application shown in 1, the PCM-B module (4) is located in the vaccine storage compartment. (2) is located at the bottom. The PCM-B module (4) is located below the PCM-A module (3) a second module containing phase-change material with different phase-change temperatures 30 It is located within the system. PCM-A module (3) high temperature buffering heat increases caused by low temperatures, PCM-B module (4) It reduces the risk of freezing. Vaccine with thermal barrier (5), PCM-A module (3) and PCM-B module (4) The thermal barrier (5) is located between the storage compartment (2) and the vaccine. It is arranged in a layer surrounding the storage compartment (2) and It prevents frostbite damage that can occur as a result of direct contact. Thermal. barrier (5), PCM-A module (3), vaccine storage compartment (2) with PCM-B module 5 It forms a physical dividing structure between them. Passive visual temperature indicator (6) on the outer carrying body (1) It is located in a suitable area visible to the user. Passive visual temperature indicator (6), any electronic measuring device, battery or in the system Visual monitoring of temperature status without the use of an external power source 10 It serves as an indicator that allows for its identification. In the example layout shown in Figure 1, the vaccine storage compartment (2) is for external transport. It is centrally located inside the body (1). PCM-A module (3), vaccine storage compartment (2) is at the top; PCM-B module (4) is at the bottom. It includes a thermal barrier (5), vaccine storage compartment (2) and PCM modules 15 It is located between the passive visual temperature indicator (6) and the outer carrying body. (1) is located on. Application example Before use, the PCM-A module (3) and PCM-B module (4) must be checked for the phase to be used. Prepared in accordance with the properties of the materials used for external transport 20 The vaccines are placed in their places inside the body (1). The vaccines are placed in the vaccine storage compartment (2) It is installed and the system is made ready for transport. Passive visual during transport. The temperature status can be visually monitored via the temperature display (6). The system, passively, without requiring any electrical connection or batteries. It is used. 25

Claims

6 REQUESTS 1. Passive vaccine transport system used for transporting temperature-sensitive vaccines. Its characteristic is; - an external transport body (1), 5 - a vaccine contained within the external transport body (1) storage compartment (2), - to check the upper temperature limit of the vaccine storage compartment (2) a positioned PCM-A module (3), - to check the lower temperature limit of the vaccine storage compartment (2) 10 a positioned PCM-B module (4), - Vaccine storage compartment with PCM-A module (3) and PCM-B module (4) (2) located between the vaccine storage compartment (2) arranged in a surrounding layer and in direct contact a thermal 15 that prevents frostbite damage that may occur as a result barrier (5), - a passive visual temperature located on the outer body (1) It is characterized by containing the indicator (6).

2. It is a passive vaccine delivery system according to Claim 1, and its characteristic is that the PCM-A module (3), a module that buffers heat increases caused by high temperatures 20 It is characterized by its...

3. It is a passive vaccine delivery system according to Claim 1, and its characteristic is that the PCM-B module (4), being a module that reduces the risk of freezing at low temperatures It is characteristic.

4. Passive vaccine delivery system according to claim 1, its feature is; thermal barrier (5), 25 PCM-A module (3) and PCM-B module (4) with vaccine storage compartment (2) It is characterized by forming a physical separating structure between them.

5. Passive vaccine delivery system according to Claim 1, its feature is; passive visual temperature. (6) of the indicator, any electronic measuring device, battery or in the system The temperature status is visually determined as 30 without the use of an external power source. by being an indicator that allows it to be monitored It is characteristic. 7 6. According to Claim 1, it is a passive vaccine delivery system, characterized by its vaccine storage function. the compartment (2) is centrally located inside the outer body (1) It is characterized by its acquisition.

7. It is a passive vaccine delivery system according to Claim 1, and its characteristic is that the system does not have any 5 designed in a passive structure that does not require an electrical connection or batteries. It is characterized by its... 15 25

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