Methods and systems for preparing oximes via ammonoximation reaction

Abstract

This invention discloses a method and system for preparing oximes via an ammonium oximation reaction. The method includes: (1) mixing a carbonyl compound, ammonia, and a circulating catalyst slurry at a specific feed ratio of the carbonyl compound to the circulating catalyst slurry to obtain a mixture stream, and then contacting the mixture stream with hydrogen peroxide to perform an ammonium oximation reaction to obtain a reaction slurry; (2) mixing the reaction slurry with an organic solvent, and then performing two-phase separation to obtain an oxime-containing organic phase and a catalyst-containing aqueous phase; (3) optionally, separating the organic phase obtained in step (2) after optional water washing to obtain an organic solvent and an oxime product; (4) filtering the aqueous phase obtained in step (2) and returning it to step (1) to provide at least a portion of the circulating catalyst slurry. The method and system for preparing oximes described in this invention significantly extend the catalyst's lifespan, improve system operational stability, reduce catalyst consumption, and produce high-quality oxime products.

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