Method for making compound
A novel synthetic route using stable triamine dicholate intermediates addresses the low purity and instability issues of existing Syn3 production, achieving higher yields and lower costs in large-scale manufacturing.
TW202631156APending Publication Date: 2026-08-01FERRING INT CENT SA
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Patent Information
- Application Number
- TW114138533
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-10-08
- Filing Date
- 2025-10-07
- Publication Date
- 2026-08-01
AI Technical Summary
Technical Problem
Existing methods for manufacturing Syn3, a surfactant-like molecule used to enhance recombinant adenoviruses and therapeutic gene vectors, suffer from low crude purity, high production costs, and instability of intermediates, particularly the 'SGB' intermediate, making large-scale production challenging and inefficient.
Method used
A novel synthetic route using a class of intermediate compounds, such as triamine dicholate (TBC) intermediates, which are stable and easier to handle, leading to improved crude purity and reduced need for purification steps, enabling higher yields and lower costs.
Benefits of technology
The novel method provides Syn3 with higher purity and yield, reducing manufacturing time and costs, and making large-scale production more feasible.
✦ Generated by Eureka AI based on patent content.
Abstract
The present disclosure relates to a novel synthetic route to a molecule. In particular, the present disclosure utilises a particular class of intermediate compounds in a novel synthesis of Syn3, or analogues or derivatives thereof.
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