Methods of treating diabetes
A dosing regimen for a long-acting insulin receptor agonist like BIF addresses the challenges of daily injections by using a loading dose followed by weekly maintenance doses to achieve rapid glycemic control and minimize side effects, ensuring fewer injections and improved blood sugar management.
TW202631183APending Publication Date: 2026-08-01ELI LILLY & CO
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Patent Information
- Application Number
- TW114140708
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-12-14
- Filing Date
- 2021-12-14
- Publication Date
- 2026-08-01
AI Technical Summary
Technical Problem
Current insulin therapies require daily injections, which can be painful and lead to unwanted side effects such as hypoglycemia and weight gain, and do not provide optimal glycemic control, especially with extended insulin activity products that may take weeks to stabilize.
Method used
A dosing regimen for a long-acting insulin receptor agonist, such as BIF, involving an initial loading dose followed by weekly maintenance doses, tailored to individual patient conditions to achieve rapid pharmacokinetic steady state and minimize risks of hypoglycemia and weight gain.
Benefits of technology
The regimen allows for fewer injections, reduces the risk of hypoglycemia and weight gain, and provides enhanced glycemic control by quickly achieving steady-state serum levels.
✦ Generated by Eureka AI based on patent content.
Abstract
Described herein are doses and dosing regimens comprising determining and administering doses of long-acting insulin receptor agonists suitable for once-weekly dosing, such as Weekly Basal Insulin-Fc (BIF).
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