VAV1 Targeted Degraders and Their Uses

TW202631596APending Publication Date: 2026-08-01TIBET HAISCO PHARM CO LTD

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Patent Information

Authority / Receiving Office: TW · TW
Patent Type: Applications
Current Assignee / Owner
Filing Date: 2025-11-28
Publication Date: 2026-08-01

Application Information

Patent Timeline

28 Nov 2025

Application

01 Aug 2026

Publication

TW202631596A

IPC: C07D401/10; A61K31/453; A61K31/454; A61K31/4545; A61K31/497; A61K31/506; A61K31/675; A61P37/00; C07D211/40; C07D401/12; C07D401/14; C07D405/10; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D421/14; C07D471/04; C07D487/04; C07F9/6558

Inventors: 李瑤; 張浩亮

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Abstract

This invention relates to a VAV1-targeting degrader and its use. In particular, this invention relates to compounds of general formula (I), or stereoisomers thereof, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, and their use in the preparation of medicaments for the treatment / prevention of VAV1-mediated diseases, wherein the substituents in general formula (I) are the same as defined in the specification.

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