Composition and method for ex vivo expansion of stem cell memory t cells
TW202631657APending Publication Date: 2026-08-01LUKAS BIOMEDICAL INC
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Patent Information
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- LUKAS BIOMEDICAL INC
- Filing Date
- 2025-01-17
- Publication Date
- 2026-08-01
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Figure TWG2TA001069579_001 
Figure TWG2TA001069579_002 
Figure TWG2TA001069579_003
Abstract
The present invention provides a composition for ex vivo expansion of memory T stem cells, comprising: a first composition, which includes CD3, CD28, interleukin-2, interleukin-7, and interleukin-15; and a second composition, which includes interleukin-2, interleukin-7, and interleukin-15. The present invention also provides a method for ex vivo expansion of memory T stem cells, comprising: culturing mononuclear cells with a medium containing the first composition to obtain activated T cells; culturing the activated T cells with a medium containing the second composition to obtain a first cell population; and culturing the obtained first cell population with a medium containing a third composition to obtain a second cell population. Therefore, the composition and method for ex vivo expansion of memory T stem cells provided by the present invention can be applied in clinical fields related to immunotherapy.
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