Methods of treating multiple sclerosis with CD19-CD20 dual car-t cells

TW202634061APending Publication Date: 2026-08-16GENENTECH INC +1
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Patent Information

Application Number
TW114144168
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-11-13
Filing Date
2025-11-12
Publication Date
2026-08-16

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Abstract

The present disclosure provides methods of treating multiple sclerosis (e.g. progressive MS or relapsing remitting MS) by administering a chimeric antigen receptor T cell (CAR-T cell) comprising an anti-CD20 chimeric antigen receptor and an anti-CD19 chimeric antigen receptor. The present disclosure also provides a dose infusion bag comprising a composition comprising CAR-T cells comprising an anti-CD20 chimeric antigen receptor and an anti-CD19 chimeric antigen receptor.
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