Multifunctional conjugates of 2,4-dinitrophenol and selective PPAR modulators, and compositions and methods thereof

TW202635622APending Publication Date: 2026-09-01SHENZHEN HIGHTIDE BIOPHARM

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Patent Information

Application Number: TW114142611
Authority / Receiving Office: TW · TW
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2024-11-07
Filing Date: 2025-11-03
Publication Date: 2026-09-01

Application Information

Patent Timeline

07 Nov 2024

Priority

03 Nov 2025

Application

TW114142611

01 Sep 2026

Publication

TW202635622A

IPC: C07C205/37; A61K31/216; A61P3/00; A61P9/00; A61P29/00

Inventors: 馬天偉; 沈錚男

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Abstract

The invention provides novel multifunctional conjugates of 2,4-dinitrophenol (DNP) and selective modulators of PPARs, and derivatives thereof. The invention also provides pharmaceutical compositions comprising a compound of the invention and methods thereof for treating various diseases and disorders associated with or related to mitochondria or mitochondrial dysfunctions (e.g., metabolism and inflammation related diseases and disorders).

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