Improved synthesis of key intermediate of KRAS g12c inhibitor compound

TW202635667APending Publication Date: 2026-09-01AMGEN INC
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Patent Information

Application Number
TW115102896
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2018-11-16
Filing Date
2019-11-15
Publication Date
2026-09-01

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Abstract

The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure, useful for the synthesis of compounds that target KRAS G12C mutations, such as.
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