Methods for the continuous preparation of antibody conjugates
TW202635718APending Publication Date: 2026-09-01WUXI XDC (SHANGHAI) CO LTD
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Patent Information
- Application Number
- TW115101732
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-09-18
- Filing Date
- 2026-01-15
- Publication Date
- 2026-09-01
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Figure TWG2TA001075154_001 
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Abstract
This invention relates to a method for the continuous preparation of antibody-drug conjugates, comprising: 1) providing an unpurified or partially purified antibody or its antigen-binding fragment thereof; 2) conjugating the unpurified or partially purified antibody or its antigen-binding fragment thereof to a payload via a linker to prepare an antibody-drug conjugate; and 3) purifying the antibody-drug conjugate. The method of this invention simplifies the process, significantly shortens the production cycle, reduces reagent consumption, and is both efficient and economical.
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