Intermediates and processes for preparing novel PRMT5 inhibitors
TW202637136APending Publication Date: 2026-09-16AMGEN INC
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Patent Information
- Application Number
- TW115103878
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-12-16
- Filing Date
- 2021-12-15
- Publication Date
- 2026-09-16
Abstract
herein are compounds of Formula I and pharmaceutically acceptable salt thereof, as well we pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure:
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