Solid preparation of nk3r antagonist

Abstract

or a pharmaceutically acceptable salt thereof as the active ingredient and a carrier material. The carrier material is selected from one, two or more of polyvinylpyrrolidone (PVP), copovidone, polyvinylpyrrolidone-vinyl acetate copolymer, hypromellose acetate succinate (HPMCAS), polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer, hypromellose (HPMC), polyethylene glycol (PEG) and ethyl cellulose (EC), which endows the drug with excellent stability, dissolution performance and therapeutic efficacy. The preparation of the present invention achieves rapid drug release, which can alleviate the oral administration burden of high-dose tablets for menopausal patients, thereby improving therapeutic compliance and treatment efficiency.

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