Tricyclic BTK degraders and their pharmaceutical applications

TW202637182APending Publication Date: 2026-09-16HAISCO PHARMACEUTICAL GROUP CO LTD
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Patent Information

Application Number
TW114147398
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-05
Filing Date
2025-12-04
Publication Date
2026-09-16
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Abstract

Tricyclic BTK degrading agents and their pharmaceutical applications, specifically relating to a compound of general formula (I-1), (I-2), (I-3), or (I-4) or its stereoisomers, tautomers, racemates, pharmaceutically acceptable salts, intermediates, and preparation methods thereof, and their use in BTK-related diseases such as tumors or autoimmune diseases, particularly in relapsed / refractory B-cell malignancies.
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