Anti-LRRC15 antibodies and uses thereof
TW202637592APending Publication Date: 2026-09-16BRISTOL MYERS SQUIBB CO
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Patent Information
- Application Number
- TW114145599
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-11-17
- Filing Date
- 2025-11-21
- Publication Date
- 2026-09-16
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Abstract
Provided herein are isolated anti-LRRC15 antibodies, antigen binding portions thereof, bispecific antibodies, and conjugates (e.g., antibody-drug conjugates), which specifically bind to LRRC15 and are internalized by LRRC15 expressing cells. Also provided are nucleic acids encoding the anti-LRRC15 antibodies and antigen binding portions, methods for treating cancer comprising administration of LRRC15-targeted antibodies, antigen binding portions thereof, bispecific antibodies, and conjugates and / or associated therapies, as well as methods of diagnosis, and kits.
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