Nitrogen-containing heterocyclic compounds with MYT1 inhibitory activity

TW202639550APending Publication Date: 2026-10-01CHUGAI PHARMA CO LTD
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Patent Information

Application Number
TW115125252
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-02-28
Filing Date
2024-02-27
Publication Date
2026-10-01

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    Figure TWG2TA001079818_003
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Abstract

A novel compound having MYT1 inhibitory activity, or a salt thereof or a solvent thereof, is provided. The compound, or a salt thereof or a solvent thereof, is represented by formula (1): [wherein, R4 is selected from the group consisting of substituted C6-C10 aryl (R4A), substituted 4-10 member heterocyclic groups, and substituted 5-10 member heteroaryl (R4HA); R5 and R6 together with the atoms bonded thereto form a substituted D ring; the D ring is selected from the group consisting of 3-10 member monocyclic alicyclic rings, benzene rings, 3-12 member monocyclic heterocycles, and 5-6 member monocyclic aromatic heterocycles (DHA); any two adjacent substituents on the D ring together with the atoms bonded thereto form a substituted E ring].
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