Method for characterizing activity of clostridial neurotoxin or identifying clostridial neurotoxin for therapeutic and / or cosmetic use, genetically engineered cell and method of producing the same, and assay for determining activity of modified or recombinant clostridial neurotoxin
TW202639844APending Publication Date: 2026-10-01IPSEN BIOPHARM LTD
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Patent Information
- Application Number
- TW115115514
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2019-06-07
- Filing Date
- 2020-06-05
- Publication Date
- 2026-10-01
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Abstract
A cell that has been genetically engineered to be highly sensitive to clostridial neurotoxin, for example, botulinum neurotoxin and tetanus neurotoxin, or modified or recombinant versions thereof. A method for making such a genetically-engineered cell and a method for using such a cell in assaying the activity of modified or recombinant clostridial neurotoxins.
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