Gluconic acid-coated selenium nanoparticles, pharmaceutical composition comprising the same, use thereof, and manufacturing method thereof

TW202641488APending Publication Date: 2026-10-16ZHENGZUAN TECHNOLOGY CO LTD
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Patent Information

Application Number
TW114112302
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Filing Date
2025-03-31
Publication Date
2026-10-16

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Abstract

Provided is a gluconic acid-coated selenium nanoparticle (GA-SeNP), which comprises a selenium nanoparticle and gluconic acid, wherein the gluconic acid is coated on the selenium nanoparticle to form a core-shell structure. GA-SeNPs can repolarize M2 macrophages into M1 macrophages and induce apoptosis of cancer cells through the generation of reactive oxygen species, thereby serving as the medicine for cancer treatment. A manufacturing method thereof is also provided.
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