Augmented acid alpha-glucosidase for the treatment of pompe disease

TW202641580APending Publication Date: 2026-10-16AMICUS THERAPEUTICS INC
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Patent Information

Application Number
TW115118575
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2016-12-08
Filing Date
2016-12-30
Publication Date
2026-10-16

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Abstract

A method for treating Pompe disease including administration of recombinant human acid α-glucosidase having optimal glycosylation with mannose-6-phosphate residues in combination with an amount of miglustat effective to maximize tissue uptake of recombinant human acid α-glucosidase while minimizing inhibition of the enzymatic activity of the recombinant human acid α-glucosidase is provided.
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