Individualized cell therapy using patient-derived antigen-specific regulatory t cells

Abstract

Compositions containing one or more peptide fragments of proinsulin for the treatment of autoimmune diseases of type 1 diabetes mellitus (T1DM), methods of using these compositions to treat autoimmune diseases of T1DM, and kits containing these compositions for the diagnosis and / or treatment of autoimmune diseases of T1DM. Compositions comprising one or more peptide fragments of preproinsulin for treating type 1 diabetes mellitus (T1DM) autoimmunity, methods of treating T1DM autoimmunity using such compositions, and kits comprising such compositions for diagnosing and / or treating T1DM autoimmunity.