Anti-april antibody, Anti-april / BAFF bispecific antibody, and preparation method therefor and use thereof

TW202641862APending Publication Date: 2026-10-16SHENYANG SUNSHINE PHARMA CO LTD
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Patent Information

Application Number
TW115101466
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-01-15
Filing Date
2026-01-14
Publication Date
2026-10-16

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Abstract

The present invention provides an anti-APRIL antibody and anti-APRIL / BAFF bispecific antibody. The bispecific antibody comprises the anti-APRIL antibody or antigen-binding fragment thereof and the anti-BAFF antibody or antigen-binding fragment thereof. The anti-APRIL / BAFF bispecific antibody of the present invention can simultaneously block the binding of dual ligands APRIL and BAFF to BCMA, and also exhibits excellent stability, thereby providing a novel solution for the prevention or treatment of diseases associated with APRIL and / or BAFF.
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