Bispecific antibody constructs that bind ALPP / alppl2 and CD3

TW202641869APending Publication Date: 2026-10-16MERCK SHARP & DOHME CORP
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Patent Information

Application Number
TW115101482
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-10-14
Filing Date
2026-01-14
Publication Date
2026-10-16

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Abstract

Bispecific antibody constructs comprising a first binding domain, which binds to human alkaline phosphatase, placental type (ALPP) and / or alkaline phosphatase, germ cell type (ALPPL2), on the surface of a tumor cell and a second binding domain, which binds to human CD3 on the surface of a T cell.
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