Uses of TSYI-PA102 to improve osteoarthritis

Abstract

This invention provides the use of Cordyceps militaris strain TSYI-PA102 for improving osteoarthritis, the accession number of which is BCRC 930232; osteoarthritis can be improved by applying Cordyceps militaris TSYI-PA102.

Claims

1. Use of Cordyceps militaris TSYI-PA102 in the preparation of a composition for improving arthritis; wherein the composition is for oral administration.

2. The use as described in claim 1, wherein the Cordyceps militaris TSYI-PA102 is a deep-culture product.

3. The use as described in claim 1, wherein the arthritis is degenerative arthritis.

4. The use as described in claim 3, wherein the composition improves pain, inflammation, swelling, or loss of articular cartilage caused by osteoarthritis.

5. The use as described in claim 1, wherein the composition reduces the inflammatory indices IL-1β, IL-6 and TNF-α.

6. The use as described in claim 1, wherein the composition is a pharmaceutical composition, a nutritional supplement, or a health food.

7. The use as described in claim 1, wherein the composition comprises a pharmaceutically acceptable carrier, excipient, or diluent.

8. The use as described in claim 1, wherein the effective dose of TSYI-PA102 in the composition is 66 mg / kg body weight (mg / kg bw) or higher.

9. The use as described in claim 1, wherein the effective dose of TSYI-PA102 in the composition is 132 mg / kg body weight (mg / kg bw) or higher.

10. The use as described in claim 1, wherein the effective dose of TSYI-PA102 in the composition is 264 mg / kg body weight (mg / kg bw) or higher.

Images