Metabolite chip detection system and operation method thereof

TWI935817BActive Publication Date: 2026-08-11CHANG GUNG UNIVERSITY
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Patent Information

Application Number
TW114120515
Authority / Receiving Office
TW · TW
Patent Type
Patents
Current Assignee / Owner
Filing Date
2025-06-02
Publication Date
2026-08-11
Estimated Expiration
2045-06-01

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    Figure TWG2TB001905756_003
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Abstract

This invention discloses a metabolite chip sensing system and its operating method. The metabolite chip sensing system includes a sensing element, a main substrate, and a display device. The sensing element includes at least two sensing areas, and the main substrate includes a charge conversion element, a processor, a signal transmission element, and an interface. A first ribbon cable connects the sensing element and the charge conversion element. A second ribbon cable connects the charge conversion element and the display device. The user drops the test solution and reagent onto the sensing area. The processor uses an algorithm to calculate the signal from the charge conversion element and, based on a certain accuracy, determines the detection data and outputs a risk level of the detection result. The test solution is urine.
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Claims

1. A metabolite wafer sensing system, comprising: a sensing element; a main substrate; wherein, The main substrate includes: a charge conversion element disposed above the main substrate and connected to the at least two sensing areas; a processor disposed above the main substrate and connected to the charge conversion element; a signal transmission element disposed above the main substrate and connected to the processor; an interface disposed above the main substrate and connected to the processor; and a display device connected to the processor; wherein the sensing element further includes a first substrate, at least one first element, a second element, and at least one insulating layer; wherein the at least one first element includes at least two pairs of first terminal interfaces and at least two pairs of first... The system comprises electrode traces and at least two pairs of sensing electrodes; wherein the at least two pairs of first endpoint interfaces, the at least two pairs of first electrode traces, and the at least two pairs of sensing electrodes are disposed on the upper surface of the first substrate; wherein each of the at least two pairs of first electrode traces is connected to each of the at least two pairs of first endpoint interfaces, and each of the at least two pairs of sensing electrodes is connected to each of the at least two pairs of first electrode traces; wherein at least one insulating layer is disposed on the upper surface of the at least two pairs of first electrode traces and the at least two pairs of sensing electrodes; wherein a second element is disposed on the upper surface of the first substrate, and the second element includes: a second endpoint interface; a second electrode trace, the second endpoint interface being connected to the second electrode trace; wherein the at least two pairs of sensing electrodes form at least two sensing regions.

2. The metabolite wafer sensing system as described in claim 1, wherein the at least two sensing areas are connected to the charge conversion element via ribbon cables.

3. The metabolite chip sensing system as described in claim 1, wherein the display device is disposed above the main substrate or a display substrate.

4. The metabolite wafer sensing system as described in claim 3, wherein the main substrate and the display substrate are circuit boards.

5. The metabolite chip sensing system as described in claim 1, wherein the processor is a microprocessor chip.

6. The metabolite chip sensing system as described in claim 1, wherein the signal transmission element is a Bluetooth® chip.

7. The metabolite wafer sensing system as described in claim 1, wherein the interface is a general purpose serial bus interface.

8. A method of operating a metabolite wafer sensing system, comprising: (A) providing the metabolite wafer sensing system as described in claim 1; (B) performing environmental calibration on the metabolite wafer sensing system; (C) dropping a test liquid into the at least two sensing areas for measurement; (D) dropping at least one reagent into the at least two sensing areas for measurement; and (E) displaying a detection result on the display device.

9. The method of operating the metabolite chip sensing system as described in claim 8, wherein the test liquid is urine.

10. The method of operating the metabolite chip sensing system as described in claim 8, wherein the at least one reagent is trimethylamine oxide oxidoreductase or creatine oxidoreductase.

Citation Information

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