Compositions containing plant extracts and / or plant-derived processed products

Abstract

The present invention provides a composition for improving sports efficiency, a composition for relieving fatigue, and a composition for improving dynamic vision, characterized in that it contains plant-derived extracts and / or plant-derived processed products.

Description

[Technical Field] This case relates to a composition for improving athletic efficiency, a composition for relieving fatigue, and a composition for improving dynamic vision. [Previous Technology] Not only for athletes undergoing intense training, but also for ordinary people in their daily activities (such as housework, carrying luggage, climbing stairs), improving exercise efficiency, relieving fatigue, and improving dynamic vision are crucial. Oxygen utilization is an indicator of energy production, and improving oxygen utilization efficiency during exercise or daily life is key to sustaining exercise without feeling fatigued or short of breath. Generally, a resting arterial oxygen saturation of 96% or higher is considered normal, but it can drop to 93-88% during intense exercise (Non-Patent Literature 1). Furthermore, arterial oxygen saturation (at rest) is approximately 97% in people in their 20s, but this value decreases with age, reaching approximately 93% in people in their 60s (Non-Patent Literature 2). That is, in addition to the rapid decrease in oxygen status during intense exercise, oxygen status can also decrease in ordinary people's daily lives due to aging, labor, severe weather (low air pressure), or sleep apnea syndrome. Since oxygen levels can decrease not only during exercise but also in everyday life, the industry is looking for a formulation that, in addition to improving oxygen utilization efficiency when oxygen levels are low, can also enhance exercise efficiency, reduce fatigue buildup, improve dynamic vision, and can be taken continuously and safely on a daily basis. Kaempferol is a type of natural flavonoid found in a variety of edible plants, including tea, broccoli, grapefruit, cabbage, kale, beans, konjac, leeks, tomatoes, strawberries, grapes, Brussels sprouts, apples, quinoa, wasabi, guava, propolis, mustard, and arugula. Regarding natural flavonoids, including kaempferol, the industry is focusing on their diverse physiological effects. Examples include kaempferol's intervention in mitochondrial function (Patent Document 1, Patent Document 2, and Non-Patent Document 3) and its influence on cellular energy consumption and thyroid hormones (Non-Patent Document 4). However, these are all in vitro studies. Patent Document 3 discloses the effect of quercetin on lactate concentration, but does not specifically describe the use of other flavonoids. [Prior Art Documents] [Patent Documents] [Patent Document 1] International Publication No. 2014 / 171333 [Patent Document 2] Japanese Patent Application Publication No. 2007-228855 [Patent Document 3] Japanese Patent Publication No. 2013-542924 [Non-Patent Documents] [Non-Patent Literature 1] Williams JH, Powers SK, Stuart MK (1986) Hemoglobin desaturation in highly trained athletes during heavy exercise. Med Sci Sports Exerc 18: 168-173 [Non-Patent Literature 2] Wilkins, RL et al. Clinical assessment in respiratory care, (2004), Relationship between Age, PaO2, and Saturation [Non-Patent Literature 3] M. Montero, CD Lobaton, E. Hernandez-Sanmiguel, et al., Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids, Biochem. J. 384 (2004) 19-24. [Non-Patent Literature 4] dα-Silva WS, Harney JW, Kim BW, Li J, Bianco SD, Crescenzi A, Christoffolete MA, Huang SA, Bianco AC 2007 The small polyphenolic molecule Kaempferol increases cellular energy expenditure and thyroid hormone activation. Diabetes 56: 767-776 [Non-Patent Literature 5] Oxygen uptake effciency slope (OUES): Its physiological basis and clinical application, Journal of Sports Medicine, Tunghai University, 11, 9-14, 1999-03, Tunghai University All prior art disclosures referenced in this specification are incorporated herein by reference. [Summary of the Invention] [The problem the invention aims to solve] The objective of this invention is to provide a composition that can inhibit or improve exercise efficiency by enhancing oxygen utilization efficiency (i.e., increasing the ability to utilize oxygen), or alleviate fatigue, or inhibit or improve dynamic vision, and can exert these effects not only under normal oxygen conditions but also under conditions of reduced oxygen conditions. [Technical Means for Solving the Problem] To address the aforementioned problems, the inventors conducted intensive research and discovered that by orally administering a composition containing kaempferol to humans, oxygen utilization efficiency increased, exercise efficiency improved, fatigue was alleviated, and dynamic vision was improved during a wide range of exercise intensities, from light exercise at the level of daily life to exercise equivalent to vigorous exercise. Furthermore, the inventors clarified that edible plants known to contain kaempferol (including kaempferol glycosides), particularly wasabi leaves, guava, black tea leaves, kale, propolis, arugula, quinoa, and mustard greens, contain abundant kaempferol or kaempferol glycosides, thus completing the invention of this invention. The invention provides the following: [1] A composition for improving exercise efficiency, comprising plant-derived extracts and / or plant-derived processed products, wherein the plant-derived extracts are selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard extract, arugula extract, and mixtures thereof, and the plant-derived processed products are selected from wasabi processed products, guava processed products, tea processed products, kale processed products, propolis processed products, mustard processed products, arugula processed products, and mixtures thereof. [2] The composition for improving exercise efficiency as described in [1], wherein the improvement in exercise efficiency is an improvement in endurance. [3] The composition for improving exercise efficiency as described in [1], wherein the improvement in exercise efficiency is a relief of asthma. [4] A composition for relieving fatigue, comprising plant-derived extracts and / or plant-derived processed products, wherein the plant-derived extracts are selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard extract, arugula extract, and mixtures thereof, and the plant-derived processed products are selected from wasabi processed products, guava processed products, tea processed products, kale processed products, propolis processed products, mustard processed products, arugula processed products, and mixtures thereof. [5] A composition for improving dynamic vision, comprising plant-derived extracts and / or plant-derived processed products, wherein the plant-derived extracts are selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard extract, arugula extract, and mixtures thereof, and the plant-derived processed products are selected from wasabi processed products, guava processed products, tea processed products, kale processed products, propolis processed products, mustard processed products, arugula processed products, and mixtures thereof. [6] The composition described in any of [1] to [5] contains wasabi extract. [7] The composition described in any of [1] to [6] contains wasabi processed product. [8] The composition described in any of [1] to [7], wherein the plant-derived extract and / or the plant-derived processed product contains kaempferol. [9] The composition described in any one of [1] to [8] is characterized by containing 0.1 mg to 200 mg of kaempferol.

[10] The composition described in any one of [1] to [9] is characterized by containing 0.5 mg to 100 mg of kaempferol.

[11] The composition described in any one of [1] to

[10] is characterized in that the kaempferol is administered at a dose of 0.1 mg to 200 mg each time.

[12] The composition described in any one of [1] to

[11] is characterized in that the kaempferol is administered at a dose of 0.5 mg to 100 mg each time.

[13] The composition described in any one of [1] to

[12] is characterized by a daily administration of 0.1 mg to 600 mg of the kaempferol.

[14] The composition described in any one of [1] to

[13] is characterized by a daily administration of 0.5 mg to 200 mg of the kaempferol.

[15] The composition described in any one of [1] to

[14] is characterized in that it is administered to a subject in a hypoxic state.

[16] The composition described in any of [1] to

[15] is a food or beverage.

[17] The composition described in any of [1] to

[15] is a pharmaceutical composition. Furthermore, this invention provides the use of plant-derived extracts and / or processed plant-derived products in the manufacture of compositions for improving athletic efficiency, relieving fatigue, or improving dynamic vision. The plant-derived extracts are selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard green extract, arugula extract, and mixtures thereof. The plant-derived processed products are selected from wasabi processed products, guava processed products, tea processed products, kale processed products, propolis processed products, mustard green processed products, arugula processed products, and mixtures thereof. Furthermore, this invention provides a method for improving exercise efficiency, relieving fatigue, or improving dynamic vision, comprising administering plant-derived extracts and / or processed plant-derived products. The plant-derived extracts are selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard extract, arugula extract, and mixtures thereof. The plant-derived processed products are selected from wasabi processed products, guava processed products, tea processed products, kale processed products, propolis processed products, mustard processed products, arugula processed products, and mixtures thereof. Furthermore, this invention provides a plant-derived extract or processed plant-derived product for improving athletic efficiency, relieving fatigue, or improving dynamic vision. The plant-derived extract is selected from wasabi extract, guava extract, tea extract, kale extract, propolis extract, mustard greens extract, arugula extract, and mixtures thereof. The plant-derived processed product is selected from processed wasabi, processed guava, processed tea, processed kale, processed propolis, processed mustard greens, processed arugula, and mixtures thereof. [Effects of the Invention] The compositions of this invention can improve oxygen utilization efficiency (the ability to utilize oxygen), thereby enhancing this efficiency in all forms of "movement," including daily activities and exercise, such as exercise that relieves asthma or improves endurance. The compositions of this invention can also be used as compositions for relieving asthma or improving endurance. Furthermore, the compositions of this invention can relieve fatigue, allowing one to perform exercise or daily chores without feeling tired. Moreover, the compositions of this invention can improve dynamic vision, for example, helping to improve performance during exercise.

Implementation Method

Claims

1. Use of a wasabi extract and / or processed wasabi for manufacturing a composition to improve athletic performance, the composition containing 2 mg to 50 mg of kaempferol, the extract being obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides, and extraction treatment, the processed wasabi being obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides without extraction treatment.

2. As requested in item 1, where the improvement in exercise efficiency is an improvement in endurance.

3. As requested in item 1, wherein the improvement in exercise efficiency is a relief of asthma.

4. Use of a wasabi extract and / or processed wasabi for manufacturing a fatigue-relieving composition containing 2 mg to 50 mg of kaempferol, wherein the extract is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides, and extraction treatment, and the processed wasabi is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides without extraction treatment.

5. Use of a wasabi extract and / or processed wasabi for manufacturing a composition for improving dynamic vision, the composition containing 2 mg to 50 mg of kaempferol, the extract being obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides, and extraction treatment, the processed wasabi being obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides without extraction treatment.

6. Use of a wasabi extract and / or processed wasabi for manufacturing an ATP-promoting composition containing 2 mg to 50 mg of kaempferol, wherein the extract is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides, and extraction treatment, and the processed wasabi is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides without extraction treatment.

7. Use of a wasabi extract and / or processed wasabi for manufacturing an oxygen utilization efficiency improvement composition containing 2 mg to 50 mg of kaempferol, wherein the extract is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides, and extraction treatment, and the processed wasabi is obtained by a method comprising enzymatic treatment and / or acid hydrolysis of wasabi to convert kaempferol glycosides to kaempferol glycosides without extraction treatment.

8. The use as claimed in any of claims 1 to 7, wherein the composition comprises wasabi extract.

9. The use as claimed in any of claims 1 to 7, wherein the composition comprises processed wasabi.

10. The use as claimed in any of claims 1 to 7, wherein the composition is administered in doses of 2 mg to 50 mg, based on the kaempferol.

11. The use as claimed in any of claims 1 to 7, wherein the composition is administered in doses of 2 mg to 25 mg, based on the kaempferol.

12. The use of any one of claims 1 to 7, wherein the composition is administered to a subject under a hypoxic state.

13. The use of any of claims 1 to 7, wherein the composition is a food or beverage.

14. The use of any one of claims 1 to 7, wherein the composition is a pharmaceutical composition.

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