Composition with enhanced plant disease control efficacy and improved vainfastness of d-tagatose

Abstract

The objective of this invention is to provide a plant disease control composition with enhanced efficacy and improved rain resistance of D-tagatose, and a method for controlling plant diseases using this composition. This invention comprises a plant disease control composition using D-tagatose as the active ingredient and including oil components and surfactants, which is effective against plant diseases, especially fungal and bacterial diseases.

Description

[Technical Field]

[0001] This invention relates to a plant disease control composition in which the plant disease control effect and rain resistance of the active ingredient are enhanced by incorporating an oil component and a surfactant into a composition containing D-tagatose as the active ingredient, and to a plant disease control method using the composition. [Previous Technology]

[0002] The purpose of pesticide use in agricultural production is to control crop diseases, pests, and weeds, thereby reducing agricultural labor, stabilizing the quality and yield of agricultural products, and ensuring safe and reliable agricultural products. Pesticides are indispensable for modern agriculture. Pesticides include herbicides, insecticides, fungicides, and plant growth regulators. Furthermore, although fungicides are used for disease control, i.e., plant disease control agents, frequent and excessive use of fungicides with the same effects targeting specific plant diseases can lead to resistance in the target plant pathogens.

[0003] On the other hand, it is now observed that consumers are paying more attention to crops where pesticide use is reduced, and society is also increasingly concerned about minimizing the environmental impact of chemically synthesized pesticides. Under these circumstances, there is a growing demand for plant disease control agents and methods that have less environmental impact than traditional chemically synthesized pesticides, possess broad-spectrum efficacy against various diseases, and are highly effective against resistant fungi that are no longer effective against existing fungicides.

[0004] D-tagatose is classified as a ketose monosaccharide, and is classified as a rare sugar that exists only in trace amounts in nature (Non-Patent Literature 1). Furthermore, the Food and Drug Administration (FDA) and the World Health Organization (WHO) have declared it to have a high level of safety (Non-Patent Literature 2, 3), and it is used as a food or food additive.

[0005] Reports have indicated that D-tagatose can be effectively used as a plant disease control agent (Patent Document 1, Non-Patent Document 4). For example, it has shown control effects against diseases caused by absolute parasites such as downy mildew (downy mildew of cucumber, downy mildew of grape, downy mildew of cabbage, etc.), powdery mildew (powdery mildew of cucumber, etc.), and rust fungi (red rust of wheat, etc.), as well as diseases caused by oomycetes such as tomato blight and Pythium. It is known to be used as a plant disease control agent (Patent Document 3, Non-Patent Document 4). Furthermore, it is known that by combining with specific fungicide components, it exhibits synergistic control effects against various plant diseases (Patent Document 3).

[0006] Regarding monosaccharides containing D-tagatose, it is known that by combining them with nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, water-soluble polymers, amino acids, amino sugars, disaccharides, or salts, the plant disease control effect of monosaccharides can be significantly enhanced, and they can be effectively used as plant disease control agents (Patent Document 2).

[0007] It is widely known that oil components can be used to enhance the efficacy of pesticides. Pesticides are typically fat-soluble compounds, and dispersing them in oil components can improve their dispersion, adhesion, leaf penetration, and local mobility. However, depending on the combination with oil components, phytotoxicity to crops can sometimes occur, so there are relatively few examples of oil-containing OD agents. Especially in oil-based suspension formulations (OD agents), the emulsification property caused by mixing oil with surfactants is important, so it is crucial to identify combinations of oil with specific surfactants.

[0008] On the other hand, D-tagatose is a highly water-soluble compound, existing in aqueous solution in an equilibrium state of α-pyranose, β-pyranose, α-furanose, β-furanose, and a linear structure. The effect of mixing highly water-soluble compounds with oil components, including chemically synthesized pesticides, on efficacy enhancement is still unclear. [Prior Art Documents] [Patent Documents]

[0009] [Patent Document 1] WO2010 / 021121 [Patent Document 2] WO2014 / 142074 [Non-Patent Document]

[0010] [Non-patent document 1] International Society of Rare Sugars. http: / / www.isrs.kagawa-u.ac.jp / definition.html (2002). [Non-patent document 2] Rulis, AM Agency response letter GRAS notice No. GRN 000078. Washington, DC: US ​​Food and Drug Administration: Center for Food Safety and Applied Nutrition: Office of Food Additive Safety. http: / / pages.citebite.com / e2f2x0h3y0tjw(2001). [Non-patent literature 3]Joint FAO / WHO expert committee on food additives sixty-third meeting.Summary and conclusions. http: / / www.fao.org / 3 / a-at878e.PDF(2004). [Non-patent literature 4]The rare sugar D-Tagatose protects plants from downy mildews and is a safe fungicidal agrochemical.Commun Biol. 2020 Aug 5; 3(1): 423. [Summary of the Invention]

[0011] [The problem that the invention aims to solve]

[0012] It is known that by combining monosaccharides containing D-tagatose with nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, water-soluble polymers, amino acids, amino sugars, disitols, or salts, the plant disease control effect of monosaccharides can be significantly enhanced (Patent Document 2). However, the effect of combining oil components with surfactants to enhance efficacy and improve rain resistance is still unclear.

[0013] It is unclear whether there are any case studies that can enhance the efficacy of the composition containing D-tagatose, oil components, and surfactants, and improve the stability, emulsification, and rain resistance of the combination of the oil components and surfactants.

[0014] There are no case studies on using garden premixes containing D-tagatose as an active ingredient, oil components, and surfactants to enhance efficacy and improve rain resistance, which is unclear.

[0015] The objective of this invention is to provide a plant disease control composition with enhanced efficacy and improved rain resistance of D-tagatin, and a method for controlling plant diseases using this composition. [Means for Solving the Problem]

[0016] In order to solve the above-mentioned problems, the inventors of this case conducted various studies on the combination of D-tagatose with oil components and surfactants. As a result, they found that by combining D-tagatose with oil components and surfactants, the plant disease control effect of D-tagatose can be enhanced to a degree that cannot be expected by the individual components, without causing phytotoxicity to plants and enhancing rain resistance, thus completing the present invention.

[0017] The present invention comprises the following (Invention 1) to (Invention 14). (Invention 1) A plant disease control composition comprising D-tagatose, at least one selected from oil components, and at least one selected from surfactants. (Invention 2) The plant disease control composition of Invention 1 above, wherein the oil component is at least one selected from the group consisting of oils, mineral oils, and essential oils. (Invention 3) The plant disease control composition of Invention 2 above, wherein the oil is a plant oil. (Invention 4) The plant disease control composition of Invention 2 above, wherein the mineral oil is a fluid paraffin. (Invention 5) The plant disease control composition of Invention 2 above, wherein the essential oil is at least one selected from the group consisting of orange oil, bergamot oil, and lavender oil. (Invention 6) The plant disease control composition of Invention 3 above, wherein the plant oil is selected from at least one of the group consisting of soybean oil, rapeseed oil, castor oil, flaxseed oil, macadamia nut oil, sunflower oil, olive oil, coconut oil, and methylated seed oil derived from vegetable oils. (Invention 7) The plant disease control composition of any one of Inventions 1 to 6 above, wherein the surfactant is selected from at least one of the group consisting of nonionic surfactants and anionic surfactants. (Invention 8) The plant disease control composition of Invention 7 above, wherein the nonionic surfactant is selected from at least one of the group consisting of polyoxyethylene alkyl ethers, polyoxyethylene sorbitan fatty acid esters, sorbitan fatty acid esters, glycerol fatty acid esters, sucrose fatty acid esters, and polyoxyethylene sorbitan fatty acid esters. (Invention 9) The plant disease control composition of Invention 7 above, wherein the anionic surfactant is selected from at least one of the group consisting of lignin sulfonates, formalin condensates of aryl sulfonates, polycarboxylate salts, α-olefin sulfonates, alkyl sulfates, sulfosuccinates, and aryl sulfonates. (Invention 9a) The plant disease control composition of any one of Inventions 1 to 6 above, wherein the surfactant is selected from at least one of the group consisting of surfactants No. 1 to 45 listed in the table below: No. surfactants 1 POE sorbitol fatty acid ester, POE hardened castor oil, dialkyl sulfosuccinate 2 POE sorbitol fatty acid ester, POE hardened castor oil, sorbitol anhydride fatty acid ester, POE sorbitol anhydride fatty acid ester, dialkyl sulfosuccinate ester 3 POE sorbitol fatty acid ester, POE hardened castor oil, sorbitol anhydride fatty acid ester, dialkyl sulfosuccinate ester 4 Anionic / nonionic surfactant mixture, solvents naphtha, 1-hexanol, naphthalene 5 Anionic / nonionic surfactant mixture, solvents naphtha, 1-hexanol, naphthalene, propylene glycol 6 POE sorbitol fatty acid ester, POE hardened castor oil, sorbitol anhydride fatty acid ester 7 POE castor oil, POE sorbitan fatty acid ester, sorbitan fatty acid ester 8 POE ether-type nonionic sorbitan fatty acid ester 9 POE(15) Castor Oil 10 POE(20) Castor oil 11 POE(30) Castor oil 12 POE(42) Castor oil 13 POE(50) Castor Oil 14 POE sorbitan lauryl ester 15 POE sorbitan palmitate 16 POE sorbitan stearate 17 POE sorbitan oleate 18 POE (sorbitan trioleate) 19 Polyoxyethylene sorbitan hexaoleate, also known as: polyethoxylated sorbitan hexaoleate 20 POE(30) Sorbitol Tetraoleate twenty one POE(40) Sorbitol Tetraoleate twenty two POE(60) Sorbitol Tetraoleate twenty three POE(6) sorbitol tetraoleate twenty four Polyoxyethylene alkyl ether 25 Polyoxyethylene oil-based ether 26 POE alkyl ethers (C12-14.2 grade) 27 POE (C12-C13) 28 POA alkyl ether 29 Diglyceride monolaurate 30 Glyceryl monolaurate 31 Sorbitol anhydride fatty acid esters 32 Sucrose fatty acid esters 33 Sodium dialkyl sulfosuccinate 34 Alkylbenzene sulfonate metal salts 35 Sodium lauryl sulfate 36 Sodium alkylnaphthalene sulfonate and formalin condensate 37 Sodium lignosulfonate 38 Sodium polycarboxylate 39 Sodium α-olefin sulfonate 40 Polyoxyethylene alkylamine 41 POE alkyl ethers 42 POE oil-based ether 43 Polyepoxide modified heptamethyltrisiloxane 44 Tetrasiloxane 45 Glycerol fatty acid esters (Invention 10) The plant disease control composition of any one of Inventions 1 to 9 and 9a above is a plant disease control agent for fungal and bacterial diseases. (Invention 11) A method for controlling plant diseases, wherein the plant disease control composition of any one of Inventions 1 to 9, 9a and 10 above is applied to the plant. (Invention 12) The plant disease control method of Invention 11 above, wherein the application to the plant is carried out by bringing the plant disease control composition into contact with the plant body, or by containing the plant disease control composition in the cultivation soil or hydroponic culture solution, thereby bringing it into contact with the roots or rhizomes of the plant. (Invention 13) The plant disease control method of Invention 11 above, wherein, in the case of application to cultivation soil or hydroponic culture solution, the plant disease control composition is applied to the soil surface, injected into the soil, or mixed with the soil; in the case of hydroponic culture solution, the plant disease control composition is diluted in the hydroponic culture solution. (Invention 14) A method of using a composition as a plant disease control agent, comprising D-tagatose, at least one selected from oil components, and at least one selected from surfactants. [Effects of the Invention]

[0018] The plant disease control composition of the present invention, comprising D-tagatose, oil components, and surfactants, exhibits stronger plant disease control effects for various plant diseases compared to the case containing only D-tagatose, without causing phytotoxicity to plants, and improves rain resistance. These effects are facts that would not have been anticipated by those skilled in the art.

Implementation Method

[0019] Next, we will explain the various terms used in this specification.

[0020] The "D-tagatose" in this invention is a monosaccharide that is a constituent element of polysaccharides or rare sugars, and is classified into hexoses and ketoses according to their chemical structure and functional groups. Although it is generally a solid powder, it also includes syrups containing D-tagatose produced by isomerizing isomerized sugars.

[0021] The "oil component" in this invention refers to "mineral oil" which is a hydrocarbon compound or mixture containing impurities derived from underground resources such as natural gas and coal, "essential oil" which is a volatile oil produced by plants, or "oil" which is a glyceride of fatty acids derived from animals and plants. "Oil" includes "animal oil" and "vegetable oil".

[0022] The "surfactant" in this invention refers to an agent added to an oil component for the purpose of emulsification, solubility, dispersion, foaming, wetting, etc. Examples of "surfactants" include: nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants.

[0023] In this invention, "plant disease" refers to symptoms or spots of systemic abnormalities such as wilting, damping-off, yellowing, shriveling, and excessive growth in crops, flowers, shrubs, and trees caused by pathogens, as well as symptoms of partial diseases such as leaf blight, leaf rot, leaf curling, branch dieback, root rot, root nodules, and galls. In other words, it refers to plant diseases. Pathogens that cause "plant diseases" mainly include fungi, bacteria, spiroplasma, phytoplasma, viruses, viroids, parasitic higher plants, and nematodes. Diseases caused by fungi are called "fungal diseases," and diseases caused by bacteria are called "bacterial diseases."

[0024] "Fungal diseases" account for approximately 80% of all pathogens causing plant diseases. Examples of fungi (pathogens) that cause fungal diseases include: Phytomyxea, oomycetes, zygomycetes, ascomycetes, basidiomycetes, and imperfect fungi. For example, Phytomyxea can be categorized as: root nodule pathogens, potato scab pathogens, and beet root rot pathogens; oomycetes can be categorized as: Phytophthora blight, downy mildew pathogens, Pythium bacteria, and Aphanomyces bacteria; zygomycetes can be categorized as: Rhizopus bacteria; and ascomycetes can be categorized as: peach leaf curl pathogens, corn and sesame leaf blight pathogens, rice frost pathogens, powdery mildew pathogens, and anthracnose pathogens. The fungi that cause red mold, rice seedling elongation, and sclerotinia rot are listed. Among basidiomycetes, rust fungi, black spore fungi, purple root rot fungi, cake rot fungi, and sheath blight fungi are listed. Among incomplete fungi, gray mold fungi, bacteria of the genus *Alternaria*, bacteria of the genus *Fusarium*, bacteria of the genus *Penicillium*, bacteria of the genus *Rhizoctonia*, and white mold fungi are listed, but not limited to these.

[0025] Bacterial diseases account for about 10% of the pathogens that cause plant diseases. Examples of bacteria (pathogens) that cause bacterial diseases include: Proteobacteria (which contains Gram-negative bacteria), Actinobacteria (which contains Gram-positive bacteria), and Firmicutes. For example, within the phylum Proteobacteria, examples of α-Proteobacteria include bacteria of the genera *Rhizobium* and *Ca. Liberibacter*; examples of β-Proteobacteria include bacteria of the genera *Acidovarax*, *Burkholderia*, and *Ralstonia*; examples of γ-Proteobacteria include bacteria of the genera *Pseudomonas*, *Xanthomonas*, and *Erwinia*; examples of Actinobacteria include bacteria of the genera *Streptomyces*, *Clavibacter*, and *Curtobacterium*; and examples of Firmicutes include bacteria of the genera *Bacillus* and *Clostridium*, but are not limited to these.

[0026] In this invention, "plant" refers to a plant that is fixed in one place and obtains nutrients from the air and water to survive, and specifically refers to a plant that survives by photosynthesis. Examples include: rice, wheat, barley, corn, grapes, apples, pears, peaches, cherries, persimmons, citrus fruits, soybeans, kidney beans, strawberries, potatoes, cabbage, lettuce, tomatoes, cucumbers, eggplants, watermelons, beets, spinach, peas, pumpkins, sugarcane, tobacco, green peppers, sweet potatoes, taro, konjac, cotton, sunflowers, tulips, chrysanthemums, lawns, and other agricultural and horticultural crops, but not limited to these.

[0027] The term "plant body" as used in this invention refers to all parts constituting the "plant," such as stems, leaves, roots, seeds, flowers, and fruits. The term "seed" in this invention refers to a plant that stores nutrients for germination and can be used for propagation in agriculture. Examples include: seeds of corn, soybeans, cotton, rice, sugar beets, wheat, barley, sunflowers, tomatoes, cucumbers, eggplants, spinach, peas, pumpkins, sugarcane, tobacco, green peppers, and rapeseed; seed tubers of taro, potatoes, sweet potatoes, and konjac; bulbs of edible lilies and tulips; and bulbs of wild garlic. Furthermore, examples include genetically modified crops created through artificial gene manipulation that do not originally exist in nature, such as soybeans, corn, and cotton that have been given herbicide resistance; rice and tobacco adapted to cold regions; seeds of corn and cotton that have been given insecticide-producing properties; and potato tubers, but not limited to these.

[0028] The "plant disease control composition" in this invention refers to a composition that controls "plant diseases" when "plants" are sick, and that controls "plant diseases" in the presence of symptoms of systemic abnormal diseases such as wilting, damping-off, yellowing, shrinkage, and excessive growth caused by various pathogens, as well as symptoms of some diseases such as spots, leaf blight, mosaic, leaf curling, branch blight, root rot, root nodules, and galls.

[0029] Next, a plant disease control composition containing the D-tagatose, oil components and surfactants of the present invention will be described.

[0030] In addition to D-tagatose as the active ingredient, the plant disease control composition of the present invention may also contain at least one sugar selected from other sugars, monosaccharides, oligosaccharides, polysaccharides, neutral sugars, acidic sugars, amine sugars, sugar alcohols, or even isomers of these, and other sugars not listed below, depending on demand. Examples of D and L-aldose include: glucose, mannose, allose, azulose, tarose, galactose, idulose, gulolose, ribose, lysose, xylose, arabinose, erythritol, threose, and glyceraldehyde. Examples of D and L-ketose include: fructose, allulose, sorbitol, xylulose, ribulose, erythritol, and dihydroxyacetone. Examples of D and L-polyols include: sorbitol, mannitol, azulose, and glutathione. Tarottiol, idutitol, Gulitol, Allitol, galactitol, arabinitol, xylitol, ribitol, erythritol, glycerol, maltitol, lactitol, inositol, quercetin; disaccharides include sucrose, maltose, lactose, cellobiose, trehalose, and barragin; trisaccharides include raffinose, panoose, pinotriose, and gentiotriose; tetrasaccharides include stachyose, but are not limited to these.

[0031] Any "oil component" may be used in the plant disease control composition of the present invention. Specifically, mineral oils may include: paraffin wax, paraffin wax, isoparaffin wax, petrolatum, ceresin and other paraffin-based solvents, cycloalkane solvents, xylene, alkylbenzene, naphthalene, alkylnaphthalene, phenylxyl ethane and other aromatic hydrocarbon solvents, but are not limited to these. Essential oils may include: orange oil, turpentine oil, peppermint oil, bergamot oil, lavender oil, lemon oil, tea tree oil, clove oil, coriander seed oil, citronella oil, thyme oil, rose oil, vetiver oil, hop oil, lemongrass oil, rosemary oil, etc., but are not limited to these. Oils may include: animal oils and vegetable oils, but are not limited to these. Animal oils may include: fish oil (whale oil, shark oil, liver oil, etc.), tallow, lard, milk fat, but are not limited to these. Examples of plant-based oils include: olive oil, palm oil, castor oil, soybean oil, rapeseed oil, macadamia nut oil, corn oil, sunflower oil, coconut oil, cocoa oil, jojoba oil, flaxseed oil, rice bran oil, cottonseed oil, sesame oil, peanut oil, wheat germ oil, angelica oil, blue thistle oil, ethyl iodized oil, shea butter, jatropha oil, tea seed oil, neem oil, babassu oil, grapeseed oil, hazelnut oil, iodized oil, tung oil, perilla oil, walnut oil, leaf oil, algae oil, mustard oil, salad oil, unsaturated fatty acids, and methylated seed oil derived from plant oils, but are not limited to these. From the perspective of enhancing plant disease control and improving rain resistance, mineral oils, oils (especially plant-based oils), and essential oils are preferable.

[0032] The "Methylated Seed Oil (hereinafter also referred to as "MSO") derived from vegetable oils" of the present invention refers to oils obtained by methylating or esterifying fatty acids contained in vegetable oils. For example, sources of vegetable oils include soybean oil, rapeseed oil, etc., and oils obtained by methylating or esterifying the fatty acids contained in these oils. Examples include methylated rapeseed oil and esterified rapeseed oil, methylated soybean oil and esterified soybean oil, methylated coconut oil and esterified coconut oil. Specific examples of MSOs include Drexel's MES-100, Stepan's STEPAN C-25, STEPAN C-42, STEPAN C-65, STEPOSOL ME, STEPOSOL SB, STEPOSOL ROE-W, and The Nisshin OilliO Group Co., Ltd.'s RCM-101, but are not limited to these.

[0033] As an oil component, it is preferable to have fluidity at room temperature. From the viewpoint of enhancing the prevention and control of plant diseases and improving rain resistance, the following are more preferably listed: fluid paraffin, orange oil, bergamot oil, lavender oil, soybean oil, rapeseed oil, castor oil, flaxseed oil, macadamia nut oil, sunflower oil, olive oil, MSO and coconut oil. The following are even more preferably listed: fluid paraffin, soybean oil and MSO, etc., but not limited to these.

[0034] The plant disease control composition of the present invention may also be used in combination of two or more of the oil components.

[0035] In the plant disease control composition of the present invention, any nonionic surfactant can be used. Specifically, examples include: acetylenic glycol surfactants, fluorinated surfactants, polysiloxane surfactants, POE ether-type nonionic surfactants, etc., such as polyoxyethylene alkyl ethers [polyoxyethylene alkyl ether (POE oil-based ether, POE alkyl ether (C12-14)].Grade 2), POE alkyl ethers (C12-C13), etc., polyoxyethylene castor oil ether, polyoxyethylene hardened castor oil ether, etc., polyoxyethylene alkylamines (polyoxyethylene alkylamines, polyoxyethylene fatty acid amides, etc.), alkyl polyglycosides (decyl polyglucoside, etc.), polyoxyethylene aryl ethers (polyoxyethylene styrene phenyl ether, polyoxyethylene alkylphenol, polyoxyethylene styrene phenyl ether, polyoxyethylene benzyl phenyl ether, polyoxyethylene benzyl phenyl ether, polyoxyethylene styrene phenyl ether formalin condensate, polyoxyethylene dialkylphenyl ether, polyoxyethylene alkylphenyl ether formalin condensate, etc.), glycerol fatty acid esters (glycerol monopalmitate, glycerol mono or distearate, glycerol monodocarboxylate, glycerol mono-12-hydroxystearate, glycerol mono or dioleate, glycerol mono or dicaprylate, glycerol mono or dicaprylate, glycerol mono or dilaurate, glycerol mono or distearate, glycerol mono or dipalmitate, glycerol mono or di-docarboxylate). Fatty acid mono- or diglycerides such as esters, diacylglycerol monolaurate, and diacylglycerol monooleate; glycerol organic acid fatty acid esters such as acetate fatty acid monoglycerides, citrate fatty acid monoglycerides, succinate fatty acid monoglycerides, lactate fatty acid monoglycerides, and diacetyl tartaric acid fatty acid monoglycerides; acetylated monoglycerides; medium-chain triglycerides, etc.); polyglycerol fatty acid esters (diglycerol monostearate, diacylglycerol monolaurate, diacylglycerol monomyristate, diacylglycerol monostearate, diacylglycerol monooleate, tetraglycerol stearate, decaglycerol laurate, polyglycerol polycarboxylate, etc.); propylene glycol fatty acid esters (propylene glycol monolaurate, propylene glycol... Monopalmitate, propylene glycol monostearate, propylene glycol monooleate, etc.), polyoxyethylene sorbitan fatty acid esters [polyoxyethylene sorbitan fatty acid esters (POE sorbitan fatty acid esters), such as polyoxyethylene sorbitan tetraoleate, etc.], sorbitan anhydride fatty acid esters (sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan tristearate, sorbitan monooleate, etc.), polyoxyethylene sorbitan fatty acid esters (polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan oleate, polyoxyethylene... Sorbitan trioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan hexaoleate, etc.; sucrose fatty acid esters (sucrose mono- or dicaprate, sucrose mono- or dilaurate, etc.); polyoxyethylene fatty acid esters (polyoxyethylene monolaurate, polyoxyethylene distearate, polyoxyethylene fatty acid ester, polyoxyethylene resin ester, polyoxyethylene fatty acid diester, etc.); polyoxyethylene polyoxypropylene block polymers (polyoxyethylene polyoxypropylene block polymers, alkyl polyoxyethylene polyoxypropylene block polymer ethers, alkylphenyl polyoxyethylene polyoxypropylene block polymer ethers, etc.); polyoxyethylene fatty acid diphenyl ethers, fatty acid diethanolamide, and alkyl imidazoline.

[0036] Preferred examples of nonionic surfactants include: polyoxyethylene alkyl ethers [especially polyoxyethylene cured castor oil ether (POE cured castor oil), polyoxyethylene castor oil ether (POE castor oil)], polyoxyethylene sorbitol fatty acid esters [especially polyoxyethylene sorbitol fatty acid esters (POE sorbitol fatty acid esters)], sorbitan fatty acid esters, glycerol fatty acid esters, sucrose fatty acid esters and polyoxyethylene sorbitan fatty acid esters (POE sorbitan fatty acid esters), POE ether-type nonionic polyoxyethylene alkyl ethers, etc., but are not limited to these.

[0037] In the plant disease control composition of the present invention, two or more non-ionic surfactants may also be combined for use.

[0038] In the plant disease control composition of the present invention, any anionic surfactant can be used as the surfactant. Specifically, examples include: lignin sulfonates (such as sodium lignin sulfonate), aryl sulfonates (such as sodium dodecylbenzene sulfonate and other alkylbenzene sulfonates; sodium alkylnaphthalene sulfonate, sodium monoalkylnaphthalene sulfonate or sodium dialkylnaphthalene sulfonate and other alkylnaphthalene sulfonates), formalin condensates of aryl sulfonates (such as sodium naphthalene sulfonate formalin condensate salt; sodium alkylnaphthalene sulfonate formalin condensate salt; sodium phenolate formalin condensate salt, etc.), α-olefin sulfonates (α-olefin sulfonate... Sodium, etc.), alkyl sulfonates (sodium alkyl sulfonate, etc.), alkyl diphenyl ether disulfonates (sodium alkyl diphenyl ether disulfonate, etc.), polyoxyethylene alkylphenyl ether sulfonates (sodium polyoxyethylene alkylphenyl ether sulfonate, etc.), polyoxyethylene alkyl ether sulfosuccinate half ester, alkyl sulfates (sodium lauryl sulfate, etc.), sulfosuccinates (dialkyl sulfosuccinates, such as sodium dialkyl sulfosuccinate, etc.), polyoxyethylene alkyl aryl ether sulfates (polyoxyethylene alkyl aryl ether sulfate, polyoxyethylene styrene phenyl ether sulfate, polyoxyethylene benzyl phenyl ether sulfate, polyoxyethylene styrene phenyl ether sulfate, etc.). Polyoxyethylene alkyl ether sulfates (such as polyoxyethylene lauryl ether sulfate), polyoxyethylene polyoxypropylene block polymer sulfates (such as polyoxyethylene polyoxypropylene block polymer sodium sulfate), polyoxyethylene alkyl ether acetates (such as polyoxyethylene lauryl ether acetate sodium salt), polyoxyethylene alkyl ether phosphates (such as polyoxyethylene alkyl ether phosphate, polyoxyethylene styrene phenyl ether phosphate, polyoxyethylene benzyl phenyl ether phosphate, polyoxyethylene alkyl phenyl ether phosphate, etc.), polyoxyethylene alkyl ether phosphates (such as polyoxyethylene alkyl phenyl ... Ethylene lauryl ether phosphate monoethanolamine salt, polyoxyethylene lauryl ether phosphate, etc.), polyoxyethylene polyoxypropylene block polymer phosphate (polyoxyethylene polyoxypropylene block polymer sodium phosphate, etc.), alkyl phosphate (alkyl phosphate, alkyl sodium phosphate, etc.), methyl taurate (oil-based methyl taurate sodium, etc.), polycarboxylate (polycarboxylate sodium, alkyl maleic acid copolymer sodium, maleic acid isobutylene copolymer, acrylic acid maleic acid copolymer sodium, polycarboxylate sodium stilbene phenyl ether sulfate ammonium salt, etc.), and fatty acid salt (semi-cured tallow fatty acid sodium soap, etc.), etc.

[0039] Preferably, anionic surfactants include: lignin sulfonates, aryl sulfonates, formalin condensates of aryl sulfonates, polycarboxylate salts, α-olefin sulfonates, alkyl sulfates and sulfosuccinates, etc. More preferably, sulfosuccinates, alkyl sulfates and aryl sulfonates, etc., and even more preferably, dialkyl sulfosuccinate, sodium lauryl sulfate and alkylbenzene sulfonates, etc., but not limited to these.

[0040] In the plant disease control composition of the present invention, two or more of the anionic surfactants may also be used in combination.

[0041] In the plant disease control composition of the present invention, any cationic surfactant and / or any amphoteric surfactant may be used as the surfactant. For example, polyoxyethylene alkylamine, polyoxyalkylene modified heptamethyltrisiloxane, tetrasiloxane or glycerol fatty acid ester may be used.

[0042] In the plant disease control composition of the present invention, regarding the surfactant, two or more surfactants selected from the group consisting of nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants may be used in combination. For example, a mixture of anionic and nonionic surfactants may be used.

[0043] The plant disease control composition of the present invention may contain only the above-mentioned D-tagatose, oil components and surfactants, and may also add solvents, anti-settling agents, defoamers, antifreeze agents, antioxidants, dispersing stabilizers, antifungal agents and thickeners commonly used in agricultural formulations as needed.

[0044] As for solvents, examples include: nitrogen-containing compounds such as N-methylpyrrolidone, N-butylpyrrolidone, and 1,3-dimethyl-2-tetrahydroimidazolone; alcohols such as methanol, ethanol, 1-propanol, and 2-ethylhexanol; ethers such as 1,4-dimethylalkanes, diethyl ether, and tetrahydrofuran; ketones such as acetone and methyl ethyl ketone; esters such as methyl lactate, ethyl acetate, and benzyl acetate.

[0045] Examples of anti-precipitating agents include: silicon dioxide, hydrophobic fumed silicon dioxide, organic bentonite, bentonite, aluminum magnesium silicate, etc.

[0046] Examples of defoamers include alcohols such as isooctadecyl alcohol and methylated polysiloxanes.

[0047] Examples of antifreeze agents include: ethylene glycol, diethylene glycol, propylene glycol, glycerin and other polyols.

[0048] As for antifungal agents, examples include: sodium benzoate, potassium sorbate, 1,2-benzisothiazolin-3-one, ethyl p-hydroxybenzoate, etc.

[0049] As for thickeners, examples include calcium stearate, etc.

[0050] However, these components are not limited to those exemplified above.

[0051] In this invention, the blending ratio of each component may vary depending on the type of blended component, formulation form, application, etc., and cannot be uniformly specified. For example, D-tagatose is 1-50 parts by weight, but is expected to be 5-40 parts by weight; oil component is 10-98.89 parts by weight, but is expected to be 30-93.9 parts by weight; surfactant is 0.01-30 parts by weight, but is expected to be 0.1-20 parts by weight. In addition, when the surfactant is a nonionic surfactant, it is more desirable to be 0.1-30 parts by weight, and even more desirable to be 1-20 parts by weight; when the surfactant is an anionic surfactant, it is more desirable to be 0.01-10 parts by weight, and even more desirable to be 0.1-5 parts by weight.

[0052] In this invention, in addition to using the above-mentioned plant disease control composition containing D-tagatose, oil components, and surfactants, compositions containing D-tagatose as an active ingredient and compositions containing oil components and surfactants can also be used simultaneously or separately. When used separately, either the composition containing D-tagatose as an active ingredient or the composition containing oil components and surfactants can be used first, followed by the other composition; either can be used preferentially. Alternatively, compositions containing D-tagatose as an active ingredient, compositions containing oil components, and compositions containing surfactants can be used simultaneously or separately. In the case of separate use, the order of use of these compositions is arbitrary. The same applies to the mixing of commercially available spreading agents containing oil components. That is, the present invention also relates to a method for enhancing the control effect of D-tagatose on plant diseases and its rain resistance, characterized by "applying D-tagatose, at least one of oil components and at least one of surfactants simultaneously or separately to the plant".

[0053] From the viewpoint of improving rain resistance, a formulation containing D-tagatose (e.g., the tagatose hydrate formulation used in the examples) is mixed with a composition containing oil components and surfactants (e.g., commercially available pesticides or spreading agents) at a ratio of D-tagatose to oil components of 1:0.1 to 10, preferably 1:0.5 to 3, more preferably 1:0.5 to 1, and most preferably 1:0.5 or 1:1. In particular, the composition preferably contains flowing paraffin or esterified or methylated vegetable oils (e.g., methylated rapeseed oil or esterified rapeseed oil MSO) as the oil component.

[0054] Commercially available pesticides and spreading agents containing oil components and surfactants that can be used in this invention include: Melo (registered trademark), Mero (registered trademark), Tipo (registered trademark), Vazyl / Oleo (registered trademark), Vegol (registered trademark), Puresspray (registered trademark), Puperior70 Oil (registered trademark), Parka (registered trademark), Enspray99 (registered trademark), Iharol (registered trademark), Prime Oil (registered trademark), Agri-Dex (registered trademark), Crop Oil Concentrate (registered trademark), Drop Zone (registered trademark), FSCOC Supreme, Herbimax, Peptoil, Superb HC, Destiny, Dyne-Amic, FS MSO Ultara, Meth Oil, MSO / MVO, Prime Oil EV, Rivet, Soy Dex Plus, Vegetable Oil, Vegetoil, Superb HC, Biotrol, Oil Chemag Extend, Chemtrol, Codacide (registered trademark), Ecotrol, Endorse, Envoy, Intac, Miller Exit, Nexustmspray Adjuvant, Nuturf (registered trademark), Driftex, ProCanoil spray oil, Protect (registered trademark) oil, Rutec Control Oil, Sacoa Xseed, Simplot Oilon, Smart Crop spray oil, Spalding canola oil spray oil conc, Spraytech oil, Stoller natural oil, Supa stik, Synertrol (registered trademark), Xtend Plant oil, Activoil, Adigor (registered trademark), Bolster, Dasher, Effectiveivoil, Fastuptm, Glysarin 704, Hasten (registered trademark), Impel, Infiltrator, Kwickin (registered trademark), Phase Dispersant Penetrant, Plantocrop, Promax, Pronto, Protect (registered trademark) Plus, Racer Ultra, RapidOil, Rocket (registered trademark), Swift, Synertrol (registered trademark) excel, Trio sterycon oil700, 4-Farmers speedy, Suffoil emulsion, Kumiai Attack Oil, Harvesat Oil, engine oil, etc., but not limited to these.

[0055] Next, a method for controlling plant diseases using the plant disease control composition comprising D-tagatose, oil and surfactant of the present invention will be described.

[0056] The application methods of the plant disease control composition of the present invention can be exemplified by: bringing the plant disease control composition into contact with plant bodies such as seeds, or by containing the plant disease control composition in cultivation soil or hydroponic culture solution, thereby bringing it into contact with the roots or underground stems of plants. Specifically, the methods can be exemplified by: distributing the plant disease control composition to the stems and leaves of individual plants, seedling box treatment, distributing it to the soil surface, mixing it with soil after distributing it to the soil surface, injecting it into the soil, mixing it with soil after injecting it into the soil, soil irrigation treatment, mixing it with soil after soil irrigation treatment, diluting it into hydroponic culture solution, spraying it on plant seeds, applying it to plant seeds, soaking it in plant seeds, or coating plant seeds with powder, etc. Any application method commonly used by those skilled in the art can achieve sufficient effectiveness.

[0057] That is, the present invention relates to a method for controlling plant diseases, characterized by applying a plant disease control composition to plants. In this method, the application to plants involves bringing the plant disease control composition into contact with the plant body, or by containing the plant disease control composition in the cultivation soil or hydroponic culture solution, so that it comes into contact with the plant roots or rhizomes. In this method, the application to cultivation soil involves treating the soil surface with the plant disease control composition, irrigating it into the soil, or mixing it into the soil. The application to hydroponic culture solution involves diluting the plant disease control composition in the hydroponic culture solution.

[0058] The application rate and concentration of the plant disease control composition of the present invention vary depending on the target crop, target disease, degree of disease occurrence, formulation of the compound, application method, and various environmental conditions. However, when distributing or irrigating, the dosage of D-tagatose is preferably 50-1,000,000 g per hectare, with a desired dosage of 100-500,000 g per hectare. Furthermore, when treating seeds, the dosage of D-tagatose is 0.001-50 g per 1 kg of seeds, preferably 0.01-10 g. When applying the plant disease control composition of the present invention to individual plants through foliar distributing, surface application, soil injection, soil irrigation, or dilution in hydroponic culture solutions, it can also be diluted to an appropriate concentration in a suitable carrier before treatment. When the plant disease control composition of this invention comes into contact with plant seeds, it can also be diluted to an appropriate concentration and then used after soaking, coating, spraying, or smearing the plant seeds. The amount of formulation used for coating, spraying, or smearing treatments is generally about 0.05% to 50% of the dry plant seed weight, with a further desired amount of 0.1% to 30%, but this amount is not limited to these ranges and can be varied depending on the formulation form and the type of plant seed being treated.

[0059] The plant disease control composition of the present invention is effective against the following types of plant diseases. Specific diseases and their pathogens are shown below, but are not limited thereto.

[0060] Rice frost (Magnaporthe grisea), sheath blight (Thanatephorus cucumeris), brown sclerotinia rot (Ceratobasidium setariae), brown small sclerotinia rot (Waitea circinata), brown sheath blight (Thanatephorus cucumeris), sclerotinia rot (Sclerotium hydrophilum), red sclerotinia rot (Wairea circinata), smut (Entyloma dactylidis), small sclerotinia rot (Magnaporthe salvinii), gray sclerotinia rot (Ceratobasidium cornigerum), sesame leaf blight (Cochliobolus miyabeanus), stripe leaf blight (Sphaerulina oryzina), rice seedling elongation disease (Gibberella fujikuroi), damping-off disease (Pythium spp., Fusarium spp., Trichoderma spp., Rhizopus spp., Rhizoctonia) solani, Mucor sp.), seedling rot (Pythium spp., Achlya spp., Dictyuchus spp.), rice false smut (Claviceps virens), black rice blast (Tilletia barclayana), brown rice (Curvularia spp., Alternaria spp.), yellowing and stunting disease (Sclerophthora macrospora), bacterial leaf blight (Xanthomonas oryzae pv. oryzae), brown streak (Acidovorax avenae subsp. avenae), inner chin browning (Erwinia ananas), seedling damping-off bacterial disease (Burkholderia plantarii), bacterial grain blight (Burkholderia glumae), leaf sheath browning (Pseudomonas fuscovaginae), rice stem blight (Pseudomonas syringae pv. oryzae), plant rot (Erwinia (chrysanthemi), Verticillium wilt (Phytoplasma oryzae), Rice stripe tenuivirus, Rice dwarf reovirus;

[0061] Powdery mildew (Blumeria graminis f.sp.hordei; f.sp.tritici), rust (Puccinia striiformis, Puccinia graminis, Puccinia recondita, Puccinia hordei), leaf spot (Pyrenophora graminea), net blotch (Pyrenophora teres), red mold (Gibberella zeae, Fusarium culmorum, Fusarium avenaceum, Monographella nivalis), snow rot (Typhula incarnata, Typhula ishikariensis, Monographella nivalis), naked black stalk disease (Ustilago nuda), fishy black stalk disease (Tilletia caries, Tilletia controversa), eye spot (Pseudocercosporella herpotrichoides), stem rot (Ceratobasidium gramineum), cloud-shaped disease (Rhynchosporium) Secalis, leaf blight (Septoria tritici), awn blight (Phaeosphaeria nodorum), seedling damping-off (Fusarium spp., Pythium spp., Rhizoctonia spp., Septoria spp., Pyrenophora spp.), seedling blight (Gaeumannomyces graminis), anthracnose (Colletotrichum graminicola), ergot (Claviceps purpurea), leaf spot (Cochliobolus sativus), black spot (Pseudomonas syringae pv. syringae);

[0062] Red mold (Gibberella zeae, etc.), damping-off (Fusarium avenaceum, Penicillium spp., Pythium spp., Rhizoctonia spp.), rust (Puccinia sorghi), sesame leaf blight (Cochliobolus heterostrophus), black smut (Ustilago maydis), anthracnose (Colletotrichum graminicola), northern leaf spot (Cochliobolus carbonum), brown streak (Acidovorax avenae subsp. avenae), bacterial streak (Burkholderia andropogonis), lodging bacterial disease (Erwinia chrysanthemi pv. zeae), wilt bacterial disease (Erwinia stewartii); downy mildew (Plasmopara viticola), rust (Physopella ampelopsidis), powdery mildew (Uncinula necator), black bean disease (Elsinoe) of grapes. ampelina, late rot (Glomerella cingulata, Colletotrichum acutatum), black rot (Guignardia bidwellii), vine rot (Phomopsis viticola), brown spot (Zygophiala jamaicensis), gray mold (Botrytis cinerea), bud blight (Diaporthe medusaea), purple root rot (Helicobasidium mompa), white root rot (Rosellinia necatrix), root crown gall (Agrobacterium vitis);

[0063] Powdery mildew (Podosphaera leucotricha), black spot (Venturia inaequalis), leaf spot (Alternaria mali), red spot (Gymnosporangium yamadae), blossom blight (Monilinia mali), rot (Valsa ceratosperma), ring spot (Botryosphaeria berengeriana), anthracnose (Colletotrichum acutatum, Glomerella cingulata), brown spot (Zygophiala jamaicensis), brown spot (Gloeodes pomigena), black spot (Mycosphaerella pomi), purple root rot (Helicobasidium mompa), white root rot (Rosellinia necatrix), rotting disease (Phomopsis mali, Diaporthe tanakae), brown spot (Diplocarpon mali), fire scorch (Erwinia Amylovora, root crown gall (Agrobacterium tumefaciens), hairy root (Agrobacterium rhizogenes); pear black spot (Alternaria kikuchiana), black spot (Venturia nashicola), red spot (Gymnosporangium asiaticum), ring spot (Botryosphaeria berengeriana f.sp. piricola), rotting disease (Phomopsis fukushii), branch blight (Erwinia sp.), root crown gall (Agrobacterium tumefaciens), rust-colored rotting disease (Erwinia chrysanthemi pv. chrysanthemi), flower rot (Pseudomonas syringae pv. syringae); Phytophthora cactorum (Phytophthora) disease of European pears. Syringae), Erwinia sp. (twig blight); Cladosporium carpophilum (peach black spot), Phopsis sp. (stem spot rot), Phytophthora sp. (peach blight).Anthracnose (Colletotrichum gloeosporioides), leaf curl (Taphrina deformans), shot-hole bacterium (Xhanthomonas campestris pv. pruni), root gall (Agrobacterium tumefaciens); Cherry anthracnose (Glomerella cingulata), sclerotinia kusanoi, gray spot (Monilinia fructicola), root gall (Agrobacterium tumefaciens), resin bacteria (Pseudomonas syringae pv. syringae); Persimmon anthracnose (Glomerella cingulata), leaf drop (Cercospora kaki; Mycosphaerella nawae), powdery mildew (Phyllactinia kakikora), root gall (Agrobacterium tumefaciens); Citrus black spot (Diaporthe citri), green mold (Penicillium) The following diseases are listed: digitatum, Penicillium italicum, Elsinoe fawcettii, Phytophthora citrophthora, Xhanthomonas campestris pv. citri, Pseudomonas syringae pv. syringae, Liberibactor asiaticus, and Agrobacterium tumefaciens.

[0064] Gray mold (Botrytis cinerea) of tomatoes, cucumbers, beans, strawberries, potatoes, cabbage, eggplants, lettuce, etc.; Sclerotinia sclerotiorum of tomatoes, cucumbers, beans, strawberries, potatoes, rapeseed, cabbage, eggplants, lettuce, etc.; Damping-off (Rhizoctonia spp., Pythium spp., Fusarium spp., Phythophthora spp., Sclerotinia sclerotiorum, etc.) of various vegetables such as tomatoes, cucumbers, beans, white radishes, watermelons, eggplants, rapeseed, green peppers, spinach, beets, etc.; Bacterial wilt (Ralstonia solanacearum) of Solanaceae plants; Downy mildew (Pseudoperonospora cubensis), powdery mildew (Sphaerotheca fuliginea), anthracnose (Colletotrichum orbiculare), and Didymella wilt of cucurbits. bryoniae, vine rot (Fusarium oxysporum), blight (Phytophthora parasitica, Phytophthora melonis, Phytophthora nicotianae, Phytophthora drechsleri, Phytophthora capsici, etc.), brown spot bacterial disease (Xhanthomonas campestris pv. cucurbitae), soft rot (Erwinia carotovora subsp. carotovora), spot bacterial disease (Pseudomonas syringae pv. lachrymans), marginal blight bacterial disease (Pseudomonas marginalis pv. marginalis), and canker (Streptomyces sp.).), hairy root disease (Agrobacterium rhizogenes), cucumber mosaic virus; tomato ring rot (Alternaria solani), leaf mold (Fulvia fulva), blight (Phytophthora infestans), wilt (Fusarium oxysporum), root rot (Pythium myriotylum, Pythium dissotocum), anthracnose (Colletotrichum gloeosporioides), canker (Clavibacter michiganensis), bacterial stem necrosis (Pseudomonas corrugata), black spot bacterial disease (Pseudomonas viridiflava), soft rot (Erwinia carotovora subsp. carotovora), leaf gall (Crynebacterium sp.), chlorosis (Phytoplasma asteris), yellowing and stunting disease (Tabaco leaf curl subgroup III geminivirus); eggplant powdery mildew (Sphaerotheca). (e.g., *Fulginea*) sooty mold (*Mycovellosiella nattrassii*), blight (*Phytophthora infestans*), brown rot (*Phytophthora capsici*), brown spot bacterial disease (*Pseudomonas cichorii*), bacterial stem necrosis (*Pseudomonas corrugata*), stem rot bacterial disease (*Erwinia chrysanthemi*), soft rot (*Erwinia carotovora subsp. carotovora*), and spot bacterial disease (*Pseudomonas sp.*).

[0065] Black spot disease (Alternaria brassicae), black rot (Xhanthomonas campestris pv. campestris), bacterial black spot disease (Pseudomonas syringae pv. maculicola), and soft rot (Erwinia carotovora) in rapeseed; black spot disease (Alternaria brassicae, etc.), white spot disease (Cercosporella brassicae), root rot (Phoma lingam), root nodule disease (Plasmodiophora brassicae), downy mildew (Peronospora parasitica), black rot (Xhanthomonas campestris pv. campestris), bacterial black spot disease (Pseudomonas syringae pv. maculicola), and soft rot (Erwinia carotovora subsp. carotovora) in cabbage; plant rot (Thanatephorus cucumeris) and wilt (Fusarium) in cabbage. oxysporum); cabbage's rump rot (Rhizoctonia solani), yellowing (Verticillium dahliae); scallion's rust (Puccinia allii), black spot (Alternaria porri), white mold (Sclerotium rolfsii), white blight (Phytophthora porri), black rot (Sclerotium cepivorum); onion's ulcer (Curtobacterium flaccumfaciens), soft rot (Erwinia carotovora subsp. carotovora), spot bacterial disease (Pseudomonas syringae pv. syringae), rot (Erwinia rhapontici), scale rot (Burkholderia gladioli), yellowing rot (Phytoplasma asteris); garlic's soft rot (Erwinia carotovora subsp. carotovora), spring rot (Pseudomonas marginalis pv.).marginalis); Soybean purple blotch (Cercospora kikuchii), black rot (Elsinoe glycines), black spot (Diaporthe phaseolorum), Rhizoctonia solani root rot, stem blight (Phytophthora sojae), downy mildew (Peronospora manshurica), rust (Phakopsora pachyrhizi), anthracnose (Colletotrichum truncatum, etc.), leaf burn (Xhanthomonas campestris pv. glycines), and leaf spot bacterial disease (Pseudomonas syringae pv. glycinea);

[0066] Anthracnose (Colletotrichum lindemuthianum), bacterial wilt (Ralstonia solanacearum) of common beans; stem rot (Pseudomonas syringae pv. phaseolicola) of rice; brown spot bacterial disease (Pseudomonas viridiflava) and leaf burn (Xhanthomonas campestris pv. phaseoli) of rice; black rot (Mycosphaerella berkeleyi), brown spot (Mycosphaerella arachidis) and bacterial wilt (Ralstonia solanacearum) of peanuts; powdery mildew (Erysiphe pisi) of peas; downy mildew (Peronospora pisi) of peas; bacterial blight (Pseudomonas syringae pv. pisi) and bacterial rot (Xhanthomonas campestris pv. pisi) of broad beans; downy mildew (Peronospora viciae) and blight (Phytophthora) of broad beans. nicotianae); summer blight (Alternaria solani), black spot (Thanatephorus cucumeris), blight (Phytophthora infestans), silver scab (Helminthosporium solani), dry rot (Fusarium oxysporum, Fusarium solani), powdery scab (Spongospora subterranea), bacterial wilt (Ralstonia solanacearum), black foot (Erwinia carotovora subsp. atroseptica), scab (Streptomyces scabies, Streptomyces acidiscabies), soft rot (Erwinia carotovora subsp. carotovora), sticky rot (Crostridium spp.), and ring rot (Clavibacter michiganensis subsp.).(sepedonicus); sweet potato damping-off (Streptomyces ipomoeae); beet diseases including brown spot (Cercospora beticola), downy mildew (Peronospora schachtii), black root rot (Aphanomyces cochioides), snake eye (Phoma betae), root crown gall (Agrobacterium tumefaciens), scabies (Streptomyces scabies), and spotted bacterial disease (Pseudomonas syringae pv. aptata).

[0067] Carrot diseases: black leaf blight (Alternaria dauci), gall (Rhizobacter dauci), root head cancer (Agrobacterium tumefaciens), Streptomyces scab (Streptomyces spp.), soft rot (Erwinia carotovora subsp. carotovora); Strawberry diseases: powdery mildew (Sphaerotheca aphanis var. aphanis), blight (Phytophthora nicotianae, etc.), anthracnose (Glomerella cingulata, etc.), fruit rot (Pythium ultimum), bacterial wilt (Ralstonia solanacearum), angular leaf spot (Xhanthomonas campestris), bud blight (Pseudomonas marginalis pv. marginalis); Tea diseases: netting disease (Exobasidium reticulatum), white star disease (Elsinoe leucospila), anthracnose (Colletotrichum). Thea-sinensis, ring spot (Pestalotiopsis longiseta), red burn (Pseudomonas syringae pv.theae), ulcer (Xhanthomonas campestris pv. theicola), and dog's nest disease (Pseudomonas sp.); tobacco red star disease (Alternaria alternata), powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum gloeosporioides), blight (Phytophthora nicotianae), wildfire disease (Pseudomonas syringae pv.tabaci), yellow spot bacterial disease (Pseudomonas syringae pv.mellea), cavity disease (Erwinia carotovora subsp. carotovora), damping-off (Ralstonia solanacearum), and tobacco mosaic virus (Tobaco mosaic virus); cotton damping-off (Fusarium) oxysporum); sclerotinia sclerotiorum and angular spot disease of sunflower (Xhanthomonas campestris pv.).Malvacearum, cavity disease (Erwinia carotovora subsp. carotovora), spot bacterial disease (Pseudomonas syringae pv. helianthi); Rose black spot (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa, etc.), blight (Phytophthora megasperma), downy mildew (Peronospora sparsa), root gall (Agrobacterium tumefaciens); Chrysanthemum brown spot (Septoria obesa), white rust (Puccinia horiana), blight (Phytophthora cactorum), spot bacterial disease (Pseudomonas cichorii), soft rot (Erwinia carotovora subsp. carotovora), root gall (Agrobacterium tumefaciens), hairy root disease (Agrobacterium rhizogenes), greening disease (Phytoplasma) aurantifolia); turf diseases including brown spot (Rhizoctonia solani), coin spot (Sclerotinia homoeocarpa), Curvularia sp. leaf blight, rust (Puccinia zoysiae), Helminthosporium leaf blight (Cochliobolus sp.), cloud-shaped blight (Rhynchosporium secalis), damping-off (Gaeumannomyces graminis), anthracnose (Colletotrichum sp.), snow-rot brown sclerotium rot (Typhula incarnata), snow-rot black sclerotium rot (Typhula ishikariensis), snow-rot large sclerotium rot (Myriosclerotinia borealis), fairy ring disease (Marasmius oreades, etc.), Pythium aphanidermatum wilt (Pyricularia grisea), and heat disease.

[0068] The plant disease control composition of the present invention is suitable for controlling diseases caused by oomycetes such as downy mildew and blight, various powdery mildews, various rusts, gray mold, apple scab, etc., and is more preferably used for controlling cucumber powdery mildew, grape downy mildew, grape powdery mildew, tomato gray mold, tomato blight, apple scab, or soybean rust. It is even more preferably used for controlling cucumber powdery mildew, grape downy mildew, grape powdery mildew, or tomato blight, but is not limited to these.

[0069] The plant disease control composition of the present invention can be mixed or used in combination with other pesticides, such as fungicides, insecticides, acaricides, nematicides, herbicides and plant growth regulators, microbial pesticides, spreading agents, soil conditioners or fertilizers, as needed.

[0070] Examples of fungicides that can be combined with the plant disease control components of the present invention include: phenylacetamide fungicides, mitosis and cell division inhibitors (MBC fungicides), succinate dehydrogenase inhibitors (SDHI agents), quinone external inhibitors (QoI agents), quinone internal inhibitors (QiI fungicides), oxidative phosphorylation deconjugation inhibitors, quinone external stigmatellin bond subsite inhibitors (QoSI agents), amino acid biosynthesis inhibitors, and protein... Biosynthesis inhibitors, signal transduction inhibitors, lipid and cell membrane biosynthesis inhibitors, demethylation inhibitors (DMI agents), amine fungicides, inhibitors of 3-keto reductase for C4-position demethylation in sterol biosynthesis, inhibitors of squalene epoxidase in sterol biosynthesis, cell wall biosynthesis inhibitors, melanin biosynthesis inhibitors, host plant resistance inducers, dithiocarbamate fungicides, phthalimide fungicides, guanidine fungicides, multi-point contact active fungicides, and other fungicides. For combination treatments of insecticides, acaricides, and nematicides, examples include: carbamate-based acetylcholinesterase (AChE) inhibitors, organophosphate-based acetylcholinesterase (AChE) inhibitors, GABA-acting chloride channel blockers, sodium channel modulators, nicotinic acetylcholine receptor (nAChR) competitive modulators, nicotinic acetylcholine receptor (nAChR) allotropic modulators, glutamic acid-acting chloride channel (GluCl) allotropic modulators, juvenile hormone analogs, nonspecific (multi-site) inhibitors, mite growth inhibitors, mitochondrial ATP synthesis enzyme inhibitors, and phosphorylation dephosphorylase inhibitors that disrupt the proton gradient. Conjugating agents, nicotinic acetylcholine receptor (nAChR) channel blockers, chitin biosynthesis inhibitors (Class 0, Class 1), dipteran insect molting inhibitors, ecdysone receptor agonists, mitochondrial electron transport chain complex III inhibitors, mitochondrial electron transport chain complex I inhibitors (METI), potential-dependent sodium channel blockers, acetyl-CoA carboxylase inhibitors, mitochondrial electron transport chain complex IV inhibitors, mitochondrial electron transport chain complex II inhibitors, ryanodine receptor modulators, modulators of unspecified target chordate organs, and other agents. The above-mentioned fungicides, insecticides, acaricides, or nematicides may be used in one or more combinations, but are not limited to these.

[0071] In terms of bactericides, examples include: Benalaxyl, Benalaxyl M or refined Benalaxyl-M or Kiralaxyl, Furalaxyl, Metalaxyl, Metalaxyl M or refined Metalaxyl-M or Mefenoxam, Oxadixyl, Ofurace, Hymexazol, Octhilinone, Bupirimate, Dimethirimol, Ethirimol, Oxolinic acid and other nucleic acid metabolism inhibitors; Mitosis and cell division inhibitors such as Benomyl, Carbendazim, Fuberidazole, Thiabendazole, Thiophagnate, Thiophagnate-methyl, Dietofencarb, Zoxamide, Ethaboxam, Pencycuron, Fluopicolide, Fluopimomide, Phenamacril, Metrafenone, and Pyriofenone; and NADH redox enzyme inhibitors such as diflumetorim, tolfenpyrad, and fenazaquin.Benodanil, Benzovindiflupyr, Bixafen, Boscalid, Carboxin, Fenfuram, Fluopyram, Flutolanil, Fluluxapyroxad, Furametpyr, Isofetamid, Isopyrazam, Mepronil, Oxycarbox Succinate dehydrogenase inhibitors (SDHI agents) include: succinate dehydrogenase inhibitors such as penthiopyrad, penflufen, pydiflumetofen, sedaxane, thifluzamide, pyraziflumid, isoflucypram, fluindapyr, inpyrfluxam, pyrapropoyne, and cyclobutrifluram. Azoxystrobin, Coumoxystrobin, Dimoxystrobin, Enoxastrobin, Famoxadone, Fenamidone, Fenaminstrobin, Flufenoxystrobin, Fluoxastrobin, Kresoxim-methyl, Mandestrobin Quinone external inhibitors (QoI agents) such as metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin, pyrametostrobin, pyraoxystrobin, pyribencarb, triclopyricarb, trifloxystrobin, and metyltetraprole; and quinone internal inhibitors (QiI agents) such as cyazofamid, amisulbrom, fenpicoxamid, and frylpicoxamid.Inhibitors of oxidative phosphorylation deconjugation such as Binapacryl, Meptyldinocap, Dinocap, Fluazinam, and Ferimzone; inhibitors of oxidative phosphorylation ATP synthesis enzymes such as fentin acetate, fentin chloride, and fentin hydroxide; inhibitors of ATP transport such as Silthiofam; inhibitors of quinone external stigmatellin bond subsites (QoSI agents) such as Ametoctradin; inhibitors of amino acid biosynthesis such as Cyprodinil, Mepanipyrim, and Pyrimethanil; and inhibitors of protein biosynthesis such as Blasticidin-S, Streptomycin, Kasugamycin, and Oxytetracycline. Mechanism transduction inhibitors such as Quinoxyfen, Proquinazid, Fenpiclonil, Fludioxonil, Chlozolinate, Dimethachlone, Iprodione, Procymidone, and Vinclozolin; and ethidium phosphate, Iprobenfos, Isoprothiolane, Pyrazophos, Biphenyl, Chloroneb, Dicloran, Quintozone (PCNB), Tecnazene (TCNB), Tolclofos-methyl, and Echlomezol. Lipid and cell membrane biosynthesis inhibitors such as etridiazole, iodocarb, propamocarb, and prothiocarb; ergosterol bond inhibitors such as streptomycin and pimaricin; and oxidized cholesterol bond protein inhibitors such as oxathiapiprolin and fluoxapiprolin.Azaconazole, Bitertanol, Bromuconazole, Cyproconazole, Difenoconazole, Diniconazole, Diniconazole-M, Epoxiconazole, Etaconazole, Fenarimol, Fenbuconazole, Fluquinconazole, Quinconazole, Flusilazole, Flutriafol, Hexaconazole, Imazalil, Imibenconazole, Ipconazole, Metconazole, Myclobutanil, Nuarimol, Oxpoconazole, Oxpoconazole fumarate Demethylation inhibitors (DMI agents) include fumarate, pefurazoate, penconazole, prochloraz, propiconazole, prothioconazole, pyrifenox, pyrisoxazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triflumizole, triforine, triticonazole, mefentrifluconazole, and ipfentrifluconazole. Amine fungicides such as Aldimorph, Dodemorph, Fenpropimorph, Tridemorph, Fenpropidin, Piperalin, and Spiroxamine; and sterol biosynthetic inhibitors such as Fenhexamid and Fenpyrazamine, which inhibit the demethylation of 3-keto reductases at the C4 position.Squalene epoxygenase inhibitors, such as pyributicarb, naftifine, and terbinafine, which inhibit sterol synthesis; cell wall synthesis inhibitors, such as polyoxins, dimethomorph, flumorph, pyrimorph, bethiavalicarb, bethivalicarb-isopropyl, ipprovalicarb, mandipropamid, and valifenalate; and melanin synthesis inhibitors, such as phthalyllide or fthalide, pyroquilone, tricyclazole, carpropamid, diclocymet, fenoxanil, and tolprocarb. Host plant resistance inducers such as Acibenzolar-S-methyl, Probenazole, Tiadinil, Isotianil, Laminarin, Dichlobentiazox, and Fosetyl-Al; Dithiocarbamate fungicides such as Mancozeb or Manzeb, Maneb, Metiram, Propineb, Thiram, Zinc thiazole, Zineb, Ziram, and Ferbam; Captan, Captafol, Folpet, and Fluorofolpet; Phthalate-imine fungicides: Guazatine, Iminoctadine, Iminoctadine albesilate, Iminoctadine triacetate, and other guanidine fungicides;Chlorothalonil, Dichlofluanid, Tolylfluanid, copper oxychloride, copper(II) hydroxide, copper hydroxide sulfate, organocopper compound, dodecylbenzenesulphonic acid bisethylenediamine copper[II] salt (DBEDC), sulfur, fluoroimide, anilazine, dithianon, chinomethionat or quinomethionate, methasulfocarb, and other multi-point contact active fungicides; cotyledon extract from lupin seedlings (BLAD), citrus extract (Extract from Swinglea glutinosa), tea extract (Extract from Melaleuca) Plant extracts such as alternifolia, plant oil mixtures (Eugenol, Geraniol, Thymol);Tecloftalam, Triazoxide, Flusulfamide, Diclomezine, Cyflufenamid, Dodine, Flutianil, Tebufloquin, Validamycins, Cymoxanil, Picarbutrazox, Quinofumelin, Aminopyrifen, Bidacetyl Pyridachlometyl, Ipflufenoquin, dipymetitrone, Flufenoxadiazam, Flumetylsulforim, Fluoxytioconazole, Metarylpicoxamid, Seboctylamine, Chloroinconazide, Flubeneteram, phosphorous acid Other fungicides include sodium phosphite, ammonium phosphite, and potassium phosphite; Trichoderma atroviride strain I-1237, strain LU132, strain SC1, strain SKT-1, strain 77B, Trichoderma asperellum strain T34, strain kd, Trichoderma harzianum strain T-22, Trichoderma virens strain G-41, etc.; Gliocladium catenulatum strain J1446, Clonostachys rosea strain CR-7, etc.; Coniothyrium minitans strain CON / M / 91-08, Talaromyces flavus strain SAY-Y-94-01, Saccharomyces cerevisae strain LAS02;Microbial fungicides, including but not limited to Bacillus amyloliquefaciens strain QST713, strain FZB24, strain MBI600, strain D747, strain F727, strain AT-332, Bacillus subtilis strain AFS032321, strain Y1336, strain HAI-0404, etc.; Pseudomonas chlororaphis strain AFS009, Streptomyces griseovirides strain K61, Streptomyces lydicus strain WYEC108, etc.

[0072] Regarding insecticides, the following can be listed: alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, fumigant, and fumigant. ormetanate, furathiocarb, isoprocarb, methiocarb, methamocarb, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC (3,5-xylyl) Carbamates such as methylcarbamate and xylylcarb are acetylcholinesterase (ACE) inhibitors; acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, dizinon, dichlorvos, didrotophos, dimethoate, dimethylvinphos, disulfoton, O-ethyl-O-4-nitrophenylphenylthiophosphonate (O-ethyl O-4-nitrophenylphenylphosphonothioate, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos. Isopropyl=O-(methoxyaminothiophosphoryl)salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathions, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, basesone Organophosphate inhibitors of acetylcholinesterase (AChE), including phoxim, pirimitos-methyl, profenofos, propetamphos, prothiofos, piraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, and vamidothion. Circular diene organochlorine GABA-active chloride ion channel blockers such as chlordane and endosulfan; phenylpyrazole (fiprol) GABA-active chloride ion channel blockers such as ethiprole and fipronil.Acrinathrin, Allethrin, Bifenthrin, Bioallethrin, Bioresmethrin, Cycloprothrin, Cyfluthrin, Cyhalothrin, Cypermethrin, Cyphenothrin [(1R)-trans-isomer], Deltamethrin, and Bayven [(EZ)-(1R)-isomer] (empenthrin[(EZ)-(1R)-isomer]), esfenvalerate, ethofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, imiprothrin, kadethrin, permethrin, esfenvalerate[(1R)-isomer] Pyrethroid sodium channel modulators include phenothrin ((1R)-trans-isomer), prallethrin, pyrethrin, resmethrin, silafluofen, tefluthrin, tetramethrin, tetramethrin ((1R)-isomer), tralomethrin, and transfluthrin. DDT (dichloro-diphenyl-trichloroethane), methoxychlor, and other DDT and methoxychlor sodium channel modulators; acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, and other neonicotinoid competitive modulators of the nicotinic acetylcholine receptor (nAChR).Nicotine and nicotine sulfate are competitive modulators of nicotinic acetylcholine receptors (nAChRs); sulfoxaflor and sulfoximine are competitive modulators of nicotinic acetylcholine receptors (nAChRs); flupyradifurone and butenolide are competitive modulators of nicotinic acetylcholine receptors (nAChRs); triflumezopyrim and other ion-dependent competitive modulators of nicotinic acetylcholine receptors (nAChRs); flupyrimin and other pyridylidene are competitive modulators of nicotinic acetylcholine receptors (nAChRs). Spinosyn (a nicotinic acetylcholine receptor (nAChR) allotropic modulators, such as spinosad and spintoxin; glutamic acid-active chloride channel (GluCl) allotropic modulators, such as abamectin, emamectin benzoate, lepimectin, and milbemectin; juvenile hormone analogs, such as hydroprene, kinoprene, methoprene, fenoxycarb, and pyriproxyfen; methyl bromide, other haloalkanes, chloropicrin, cryolite, sulfuryl fluoride, borax, boric acid, and disodium octaborate. Other non-specific (multi-site) inhibitors such as octaborate, sodium metaborate, meta-sodium metaborate, artar emetic, dazomet, and metham sodium; TRPV channel modulators for the chordal organs such as pymetrozine, pyrifluquinazon, and afidopyropen; mite growth inhibitors targeting CHS1 such as clofentezine, diflovidazin, hexythiazox, and etoxazole; BacillusThe following are examples of insect midgut membrane disruptors derived from microorganisms: *Bacillus thuringiensis subsp. Israelensis*, *Bacillus thuringiensis subsp. Aizawai*, *Bacillus thuringiensis subsp. Kurstaki*, *Bacillus thuringiensis subsp. Tenebrionis*, and proteins contained in Bt crops: Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Ab1 / Cry35Ab1, etc.; *Difenthiuron*, azocyclotin, cyhexatin, fenbutatin oxide, propargite, tetradifon, etc., inhibitors of mitochondrial ATP synthesis enzymes. Phosphorylation deconjugating agents that disrupt the proton gradient, such as chlorfenapyl, DNOC (dinitro-ortho-cresol), and sulfluramid; nicotinic acetylcholine receptor (nAChR) channel blockers, such as bensultap, cartap hydrochloride, thiocyclam, and thiosultap-sodium; and chitin biosynthesis inhibitors acting on CHS1, such as bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, and triflumuron. Class 1 chitin biosynthesis inhibitors such as buprofezin; Diptera molting inhibitors such as cyromazine; Ecdysone receptor agonists such as chromafenozide, halofenozide, methoxyfenozide, and tebufenozide; Octopus amine receptor agonists such as amitraz.Inhibitors of mitochondrial electron transport chain complex III, such as hydramethylnon, acequinocyl, fluacrypyrim, and bifenazate; Inhibitors of mitochondrial electron transport chain complex I, such as fenazaquin, fenpyroximate, pyridaben, pylimidifen, tebufenpyrad, tolfenpyrad, and rotenone; Potentially dependent sodium channel blockers, such as indoxacarb and metaflumizone; Acetyl-CoA carboxylase inhibitors, such as spirodiclofen, spiromesifen, spiropidion, and spirotetramat; Aluminum phosphide and calcium phosphide. Inhibitors of mitochondrial electron transport chain complex IV, such as phosphide, phosphine, zinc phosphide, calcium cyanide, sodium cyanide, and potassium cyanide; inhibitors of mitochondrial electron transport chain complex II, such as cyenopyrafen, cyflumetofen, and pyflubumide; ryanodine receptor modulators, such as chlorantraniliprole, cyantraniliprole, cyclaniliprole, flubendiamide, and tetraniliprole; and non-specific organ modulators, such as flonicamid. Allotropic regulators of GABA-active chloride ion channels, such as broflanilide, fluxametamide, and isocycloseram; baculoviruses such as Cydia pomonella GV, Thaumatitibia leucotreta GV, Anticarsia gemmatalis MNPV, and Helicoverpa armigera NPV; GS-ω / κHXTX-Hv1a peptide and other nicotinic acetylcholine receptor (nAChR) allotropic modulators - site II; acynonapyr and other calcium-activated potassium channel (KCa2) modulators; floctoquin and other mitochondrial electron transport chain complex III inhibitors; target site not specified; azadirachtin, benzoximate, phenisobromolate, chinomethionat, dicofol, lime-sulfur mixture (CaSx), mancozeb, pyridalyl, sulfur, bromopropylate, Burkholderia spp. (Zap), Chenopodium ambrosioides near ambrosioides extract. Extracts), fatty acid monoesters with glycerol or propanediol, neem oil, Beauveria bassiana strains, Metarhizium anisopliae strain F52, Paecilomyces fumosoroseus Apopka strain 97, diatomite, dicyclanil, dinobuton, dinocap, hydrogen cyanide, methyl iodide, karanjin, mercury chloride, methyl isothiocyanate, pentachlorophenol, phosphine, piperonyl butyl etherbutoxide, polynactins, sabadilla, sulcofuron-sodium, tribufos, aldrin, amidithion, amidothioate, aminocarb, amiton, aramite, athidathion, azothoate, barium polysulfide polysulphide, benclothiaz, 5-(1,3-benzodioxole-5-yl)-3-hexylcyclohexa-2-enone, 1,1-bis(4-chlorophenyl)-2-ethoxyethanol, butonate, butopyronoxyl, ethyl 2-(2-butoxyethoxy)thiocyanate thiocyanate), camphechlor, chlorbenside, chlordecone, chlordimeform, chlorfenethol, chlorfenson, fluazuron, metaldehyde, bialaphos, levamisol, amidoflumet, pirafluprole, pyriprole, tralopyril, flupyrazofos, diofenolan, chlorobenzilate, flufenzine, benzomate Flufenerim, albendazole, oxibendazole, fenbendazole, metam-sodium, 1,3-dichloropropene, ethylene dibromidedibromide, acrylonitrile, bis(2-chloroethyl) ether, 1-bromo-2-chloroethane, 3-bromo-1-chloroprop-1-ene, bromocyclen, carbon disulfide, carbon tetrachloride, nemadectin, cymiazole, cytokinin, 2-(octylthio)ethanol, potassium oleate, sodium oleate, machine oil, tar oil, anabasine, morantel tartrate, pyrethrum, rapeseed oil, soybean lecithin Lecithin, starch, hydroxypropyl starch, decanoyloctanoylglycerol, diatomite, tripropyl isocyanurate (TPIC), 1,3-Dichloropropene (DD), peroxocarbonate, MB-599 (verbutin), bis(2,3,3,3-tetrachloropropyl)ether, DCIP (bis(2-chloro-1-methylethyl)ether), ENT-8184 (N-(2-Ethylhexyl)bicyclohept-5-ene-2,3-dicarboximide), Bayer 22408 (O,O-diethyl O-naphthalimido phosphorothioate), Bayer32394 (tris(1-dodecyl-3-methyl-2-phenylbenzimidazolium)hexacyanoferrate), dicloromezotiaz, fluazaindolizine, cyhalodiamide, tioxazafen, fluhexafon, fluralaner, tetrachlorantranil iprole, sarolaner, lotilaner, tigolaner, cycloxaprid, fluensulfone, benzpyrimoxan, tyclopyrazoflor, oxazosulfyl, dimpropyridaz, cyproflanilide, nicoflupr ole), cyclobutrifluram, cycloxylidin, paichongding, guadipyr, cyetpyrafen, flupentiofenox, pyriminostrobin, chloroprallethrin, kappa-bifenthrin, kappa-tefluthrin, heptafluthrin, spirobudifen, tiorantraniliprole, trifluenfuronate, indazapyroxamet, fenmezoditiaz, fluchlordiniliprole, spiroxamat. [Example]

[0073] The detailed contents of the plant disease control composition of the present invention are illustrated by means of examples and test examples. However, the present invention is not limited by these examples and test examples.

[0074] The oil components and surfactants used in the examples and test cases are shown in Tables 1 and 2. However, the present invention is not limited thereto.

[0075] [Table 1] Table 1. List of Oil Components name Major Categories Chinese Classification Subcategories Oil A mineral oil mineral oil Flowing paraffin Oil B essential oils essential oils Orange oil Oil C Bergamot oil Oil D Lavender oil Oil E grease Vegetable oils soybean oil Oil F rapeseed oil Oil G castor oil Oil H Flaxseed oil Oil I Macadamia nut oil Oil J Sunflower oil Oil K olive oil Oil L Coconut oil Oil M Methylated fatty acid oil (MSO)

[0076] [Table 2-1]

[0077] [Table 2-2]

[0078] [Table 2-3]

[0079] [Table 2-4]

[0080] Furthermore, in the following examples and test cases, "parts" means "parts by mass".

[0081] [Example 1] D-tagatose (40 parts), soybean oil (52.5 parts) as an oil component, and Solpol 4320 (7.5 parts) as a surfactant were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 1 are shown in Table 3.

[0082] [Examples 2-23] The plant disease control pesticide composition was obtained in the same manner as in Example 1, using D-tagatose, oil components, and surfactants as shown in Table 3. The test results of Examples 2-23 are shown in Table 3.

[0083] [Example 24] D-tagatose (40.6 parts), soybean oil (51.86 parts) as an oil component, EMAL 10PT (0.13 parts) and Solpol CA-15 (7.41 parts) as surfactants were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 24 are shown in Table 4.

[0084] [Examples 25-43] Plant disease control compositions were obtained in the same manner as in Example 24, using D-tagatose, oil components, and surfactants as described in Table 4. The experimental results of Examples 25-43 are shown in Table 4.

[0085] [Example 44] D-tagatose (40.6 parts), soybean oil (51.9 parts) as an oil component, and New Calgen 110 (7.5 parts) as a surfactant were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 44 are shown in Table 5.

[0086] [Examples 45-64] Plant disease control compositions were obtained in the same manner as in Example 44, using D-tagatose, oil components, and surfactants as described in Table 5. The experimental results of Examples 45-64 are shown in Table 5.

[0087] [Example 65] D-tagatose (40.6 parts), soybean oil (53.57 parts) as the oil component, New Calgen 110 (5.0 parts) and New Calgen EP-60P (0.83 parts) as surfactants were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 65 are shown in Table 6.

[0088] [Examples 66-162] Plant disease control compositions were obtained in the same manner as in Example 65, using D-tagatose, oil components, and surfactants as described in Table 6. The experimental results of Examples 66-162 are shown in Table 6.

[0089] [Example 163] D-tagatose (40.0 parts), fluid paraffin (52.5 parts) as an oil component, and Solpol 4273 (7.5 parts) as a surfactant were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 163 are shown in Table 7.

[0090] [Examples 164-232] Plant disease control pesticide compositions were obtained in the same manner as in Example 163, using D-tagatose, oil components, and surfactants as described in Table 7. The test results of Examples 164-232 are shown in Table 7.

[0091] [Example 233] D-tagatose (40.6 parts) and fluidized paraffin (59.4 parts) as an oil component were mixed in a mortar until homogeneous to obtain a plant disease control composition. The experimental results of Example 233 are shown in Table 8.

[0092] [Examples 234-328] Plant disease control compositions were obtained in the same manner as in Example 233, using D-tagatose, oil components, and surfactants as described in Table 8. The experimental results of Examples 234-328 are shown in Table 8.

[0093] Evaluation Methods for Plant Disease Control Tests [Experiments 1-7] In these experiments, control tests were conducted on cucumber powdery mildew (CPM), grape downy mildew (VDM), grape powdery mildew (VPM), tomato gray mold (TGM), tomato blight (LB), apple scab (AS), and soybean rust (SbR). The details of the experimental methods are shown below.

[0094] (Cucumber Powdery Mildew: CPM) The test plants (cucumber variety: Sagami Hanshiro) were sown and cultivated until one true leaf unfolded. In the experiment, diluted solutions (2.5 ml / pot) were dispersed using water to achieve the predetermined concentration. For seedlings one day after dispersal, a suspension of conidia of 1.0 x 10⁵ cells / ml of *Podosphaera xanthii* was sprayed for inoculation. The severity of disease was assessed 7 days later to evaluate the effectiveness.

[0095] (Grape Downy Mildew: VDM) After sowing, the test plants (grape variety: Muscat) were cultivated until they had 3-4 true leaves. In the experiment, diluted solutions (2.5 ml / pot) were dispersed with water to a predetermined concentration. For seedlings one day after dispersal, a suspension of 1.0 x 10⁴ asci / ml of Plasmopara viticola was sprayed for inoculation. The seedlings were placed in an inoculation room at 20°C for 24 hours to induce disease. The severity of disease was assessed 10 days after inoculation to evaluate the effectiveness.

[0096] (Grape Powdery Mildew: VPM) After sowing, the test plants (grape variety: Muscat) were cultivated until they had 3-4 true leaves. In the experiment, diluted solutions (2.5 ml / pot) were dispersed with water to a predetermined concentration. For seedlings one day after dispersal, a suspension of conidia of *Uncinula necator* at 1.0 x 10⁵ cells / ml was sprayed for inoculation. The seedlings were placed in an inoculation room at 20°C for 24 hours to induce disease. The severity of disease was assessed 10 days after inoculation to evaluate the effectiveness.

[0097] (Tomato Gray Mold: TGM) After sowing, the test plants (tomato variety: Large Fushou) were cultivated until they had three true leaves. In the experiment, diluted solutions (2.5 ml / jar) were dispersed using water to achieve the predetermined concentration for each formulation. For seedlings one day after dispersal, inoculation was performed by spraying with conidia of 1.0 x 10⁵ spores / ml of *Botrytis cinerea*, and the inoculation room was kept at 23°C for 48 hours to induce disease. The severity of disease was assessed two days after inoculation to evaluate the effectiveness.

[0098] (Tomato Late Blight: LB) After sowing, the test plants (tomato variety: Large Fushou) were cultivated until they had three true leaves. In the experiment, diluted solutions (2.5 ml / pot) were dispersed using water to achieve the predetermined concentration. For seedlings one day after dispersal, a suspension of 1.0 x 10³ cells / ml of Phytophthora infestans was sprayed for inoculation. The seedlings were placed in an inoculation room at 20°C for 24 hours to induce disease. The severity of disease was assessed 7 days after inoculation to evaluate the effectiveness.

[0099] (Apple Scab: AS) After sowing, the test plants (apple variety: Wanglin) were cultivated until they had 4-5 true leaves. In the experiment, a diluted solution (2.5 ml / pot) of each prescription was dispersed using well water to a predetermined concentration. For seedlings one day after dispersal, a suspension of conidia of 1.0 x 10⁵ spores / ml of *Venturia inaequalis* was sprayed for inoculation. The seedlings were placed in an inoculation room at 20°C for 24 hours to induce disease. The severity of disease was investigated 10 days after inoculation to evaluate the effectiveness.

[0100] (Soybean Rust: SbR / Soybean Rust) After sowing, the test plants (soybean variety: Yanli) were cultivated until two true leaves unfolded. In the experiment, diluted solutions (2.5 ml / pot) were dispersed using well water to achieve the predetermined concentration. For seedlings one day after dispersal, a suspension of 1.0 x 10⁵ cells / ml of soybean rust fungus (Phakopsora pachyrhizi) was sprayed for inoculation. The inoculation room was placed at 20°C for 24 hours to induce disease. The severity of disease was assessed 7 days after inoculation to evaluate the effectiveness.

[0101] For disease control trials evaluated using the above method, the following indicators are used to evaluate the severity of disease. Furthermore, the control price is calculated based on the severity of disease. [Severity of Disease] 0: No disease 0.1: Diseased area approximately 3% 0.3: Diseased area approximately 10% 0.8: Diseased area approximately 25% 1.5: Diseased area approximately 50% 2: Diseased area approximately 70% 3: Diseased area approximately 95% [Control Price] Control Price = 100 { 1 - ( n / N )} N = Severity of disease in untreated areas, n = Severity of disease in each area Additionally, areas where no trial was conducted are recorded as nt, and areas where the trial was not successful are recorded as -. Compared to the D-tagatose hydrate formulation (in Test Examples 1-6, the formulation described in WO2014 / 142074 was used, which included: 80% D-tagatose, 0.25% New Calgen SX-C, 0.25% EMAL 10PT, and 5% MORWET D425; in Test Example 7, the formulation described in WO2014 / 142074 was used, which included: 24% D-tagatose, 0.25% New Calgen SX-C, 5% EMAL 10PT, and 5% MORWET D425), the degree to which the formulation of the present invention improves the potency (potency index) was evaluated using the following indicators. 0: The efficacy is lower than that of the D-tagag syrup formulation. 1: An improvement in efficacy was observed compared to the D-tagag syrup formulation (improvement of 1 or more but less than 10). 2: A significant improvement in efficacy was observed compared to the D-tagag syrup formulation (improvement of 10 or more).

[0102] Evaluation Method for Rain Tolerance Test [Examples 1-7] Rain tolerance tests were conducted on cucumber powdery mildew (CPM), grape downy mildew (VDM), grape powdery mildew (VPM), and tomato blight (LB). The details of the test methods are shown below.

[0103] (Cucumber Powdery Mildew Rain Fastness Test: CPM RF) The test plants (cucumber variety: Sagami Hanbare Nobuyoshi) were sown and cultivated until one true leaf unfolded. In the experiment, a diluted solution (2.5 ml / jar) of each formulation was dispersed. For seedlings one day after dispersal, after a 20 mm rainfall, a suspension of 1.0 x 10⁵ cells / ml of cucumber powdery mildew fungus (Sphaerotheca cucurbitae) was sprayed for inoculation. The severity of disease was assessed 7 days later to evaluate the effectiveness.

[0104] (Grape Downy Mildew: VDM RF / Vine Downy Mildew Rain Fastness) After sowing, the test plants (grape variety: Muscat) were cultivated until they had 3-4 true leaves. In the experiment, diluted solutions (2.5 ml / pot) were dispersed with water to a predetermined concentration. For seedlings one day after dispersal, after a 20 mm rainfall, a suspension of 1.0 x 10³ asci / ml of *Plasmodpara viticola* was sprayed for inoculation. The inoculation room was placed at 20°C for 24 hours to induce disease. The severity of disease was assessed 10 days after inoculation to evaluate the effectiveness.

[0105] (Grape Powdery Mildew: VPM RF / Vine Powdery Mildew Rain Fastness) After sowing, the test plants (grape variety: Muscat) were cultivated until they had 3-4 true leaves. In the experiment, diluted solutions (2.5 ml / jar) were dispersed with water to a predetermined concentration. One day after dispersal, seedlings were sprayed with a suspension of 1.0 x 10⁵ asci / ml of Uncinula necator, the grape powdery mildew fungus, for inoculation after a 20 mm rainfall. The severity of disease was assessed 10 days after inoculation to evaluate the effectiveness.

[0106] (Tomato Phytophthora: LB RF / Late Blight Rain Fastness) After sowing, the test plants (tomato variety: Large Fushou) were cultivated until they had three true leaves. In the experiment, diluted solutions (2.5 ml / pot) were dispersed using water to achieve the predetermined concentration. One day after dispersal, seedlings were inoculated by spraying with a suspension of 1.0 x 10³ cells / ml of Phytophthora infestans asci. The inoculation was then placed in an inoculation room at 20°C for 24 hours to induce disease. The severity of disease was assessed 7 days after inoculation to evaluate the effectiveness.

[0107] The rain resistance of the plant disease control agent containing D-tagatose, oil components, and surfactants against cucumber powdery mildew, grape downy mildew, and grape powdery mildew was evaluated using the following indicators. Compared to the D-tagatose hydrate formulation (in Test Examples 1-6, the formulation using WO2014 / 142074 was used, which included: D-tagatose 80%, New Calgen SX-C 0.25%, EMAL 10PT 0.25%, and MORWET D425 5%; in Test Example 7, the formulation using WO2014 / 142074 was used, which included: D-tagatose 24%, New Calgen SX-C 0.25%, EMAL 10PT 5%, and MORWET D425 5%), the degree to which the formulation of the present invention improves rain resistance was evaluated using the following indicator (control valence index). 0: Same level of rain resistance as D-tagatose hydrate formulation; 1: Improved rain resistance compared to D-tagatose hydrate formulation (prevention and control valence above 1).

[0108] [Experimental Example 1] Evaluation of a plant disease control agent containing D-tagatose, oil components, and multiple surfactants. The plant disease control agent prepared in the evaluation example, containing D-tagatose, oil components (soybean oil or fluidized paraffin), and multiple surfactants (nonionic surfactants and anionic surfactants), was evaluated for its efficacy and rain resistance against diseases such as cucumber powdery mildew. The degree of improvement in control efficacy and rain resistance compared with the D-tagatose hydrate formulation, as described in the evaluation methods for plant disease control and rain resistance tests, was used as the evaluation index. The results are shown in Table 3.

[0109] [Table 3]

[0110] This plant disease control agent contains D-tagatose, oil components (soybean oil or fluid paraffin), and various surfactants (nonionic surfactants and anionic surfactants). Compared with the D-tagatose hydrate formulation, it shows significant improvements in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple scab, and soybean rust.

[0111] [Experimental Example 2] Evaluation of Plant Disease Control Agent Containing D-tagatose, Soybean Oil, and Nonionic Surfactants The plant disease control agent containing D-tagatose, soybean oil, and nonionic surfactants prepared in this evaluation example was used to assess its efficacy and rain resistance against diseases such as cucumber powdery mildew. Similar to Experimental Example 1, the degree of improvement in control efficacy and rain resistance was used as indicators for evaluation. The results are shown in Table 4.

[0112] [Table 4]

[0113] A plant disease control agent containing D-tagatose, soybean oil, and nonionic surfactants, compared with the D-tagatose hydrate formulation, shows significant improvement in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple black spot, and soybean rust.

[0114] [Experimental Example 3] Evaluation of Plant Disease Control Agents Containing D-Tagatose, Soybean Oil, and Surfactants (Nonionic and Anionic Surfactants) The plant disease control agents prepared in this evaluation example, containing D-tagatose, soybean oil, and surfactants (nonionic and anionic surfactants), were evaluated for their efficacy and rain resistance against diseases such as cucumber powdery mildew. Similar to Experimental Example 1, the degree of improvement in control titer and rain resistance were used as indicators for evaluation. The results are shown in Table 5.

[0115] [Table 5]

[0116] A plant disease control agent containing D-tagatose, soybean oil, and surfactants (nonionic and anionic surfactants) shows significant improvement in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple black spot, and soybean rust compared to the D-tagatose hydrate formulation.

[0117] [Experimental Example 4] Evaluation of Plant Disease Control Agents Containing D-Tagatose, Soybean Oil, and Various Surfactants The plant disease control agents prepared in this evaluation example, containing D-tagatose, soybean oil, and various surfactants, were used to assess their efficacy and rain resistance against diseases such as cucumber powdery mildew. Similar to Experimental Example 1, the degree of improvement in control titer and rain resistance were used as indicators for evaluation. The results are shown in Table 6.

[0118] [Table 6-1]

[0119] [Table 6-2]

[0120] [Table 6-3]

[0121] A plant disease control agent containing D-tagatose, soybean oil, and various surfactants. Compared with the D-tagatose hydrate formulation, it shows significant improvement in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple black spot, and soybean rust.

[0122] [Experimental Example 5] Evaluation of Plant Disease Control Agents Containing D-Tagatose, Flowable Paraffin, and Surfactants (Nonionic and Anionic Surfactants) The plant disease control agents prepared in the evaluation examples, containing D-tagatose, flowable paraffin, and surfactants (nonionic and anionic surfactants), were evaluated for their efficacy and rain resistance against diseases such as cucumber powdery mildew. Similar to Experimental Example 1, the degree of improvement in control titer and rain resistance were used as indicators for evaluation. The results are shown in Table 7.

[0123] [Table 7-1]

[0124] [Table 7-2]

[0125] A plant disease control agent containing D-tagatose, fluidized paraffin, and surfactants (nonionic surfactants and anionic surfactants) shows significant improvement in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple black spot, and soybean rust compared to the D-tagatose hydrate formulation.

[0126] [Experimental Example 6] Evaluation of Plant Disease Control Agents Containing D-Tagatose, Various Oil Components, and Surfactants (Nonionic and Anionic Surfactants) The plant disease control agents prepared in this evaluation example, containing D-tagatose, various oil components, and surfactants (nonionic and anionic surfactants), were evaluated for their efficacy and rain resistance against diseases such as cucumber powdery mildew. Similar to Experimental Example 1, the degree of improvement in control titer and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 8.

[0127] [Table 8-1]

[0128] [Table 8-2]

[0129] [Table 8-3]

[0130] A plant disease control agent containing D-tagatose, various oil components, and surfactants (nonionic surfactants and anionic surfactants). Compared with the D-tagatose hydrate formulation, it shows significant improvement in efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato blight, apple black spot, and soybean rust.

[0131] [Experimental Example 7] Evaluation of the plant disease control agent obtained by pre-mixing D-tagatose hydrate formulation with a commercially available spreading agent containing oil components and surfactants for diseases such as cucumber powdery mildew. The efficacy and rain resistance of the plant disease control agent obtained by pre-mixing D-tagatose hydrate formulation with a commercially available spreading agent containing oil components and surfactants for diseases such as cucumber powdery mildew were evaluated. Similar to Experimental Example 1, the degree of improvement in control efficacy and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 9.

[0132] [Table 9]

[0133] Rain resistance tests using cucumber powdery mildew, grape downy mildew, grape powdery mildew, and tomato blight as indicators, with D-tagatose hydrate formulation mixed with commercially available spreading agents containing oil components and surfactants at a ratio of 1:1 or 1:0.5, confirmed that mixing with spreading agents containing esterified or methylated vegetable oils or spreading agents containing flowing paraffin significantly improved rain resistance. [Industrial Applicability]

[0134] This invention provides a plant disease control composition containing oil components and surfactants that enhance the plant disease control effect of D-tagatose, a plant disease control method using the plant disease control composition, and a method for enhancing the plant disease control effect and / or rain resistance of D-tagatose. The plant disease control composition can be used as a foliar spray, soil treatment agent, or seed treatment agent without causing phytotoxicity to the host plant and can control various plant diseases.

Claims

1. A plant disease control composition comprising D-tagatose, at least one selected from an oil component, at least one selected from a nonionic surfactant, and at least one selected from anionic surfactant; wherein the oil component is at least one selected from the group consisting of oils, mineral oils, and essential oils; the nonionic surfactant is at least one selected from the group consisting of polyoxyalkylene ethers, polyoxyalkylene sorbitan fatty acid esters, sorbitan fatty acid esters, glycerol fatty acid esters, sucrose fatty acid esters, and polyoxyethylene sorbitan fatty acid esters; and the anionic surfactant is at least one selected from the group consisting of alkyl sulfates and sulfosuccinates.

2. As in the plant disease control composition of Request 1, wherein the oil is a vegetable oil.

3. As in the plant disease control composition of claim 1, wherein the mineral oil is a fluid paraffin.

4. The plant disease control composition of claim 1, wherein the essential oil is selected from at least one of the group consisting of orange oil, bergamot oil and lavender oil.

5. The plant disease control composition of claim 2, wherein the plant oil is selected from at least one of the group consisting of soybean oil, rapeseed oil, castor oil, flaxseed oil, macadamia nut oil, sunflower oil, olive oil, coconut oil and methylated seed oil derived from vegetable oils.

6. Any plant disease control composition as described in any of the claims 1 to 5 is a plant disease control agent for fungal and bacterial diseases.

7. A method for controlling plant diseases, which involves applying to plants the plant disease control composition as described in any one of claims 1 to 6.

8. The plant disease control method of claim 7, wherein the application to the plant is by bringing the plant disease control component into contact with the plant body, or by containing it in the cultivation soil or hydroponic culture solution and bringing it into contact with the plant roots or rhizomes.

9. As in the plant disease control method of claim 7, in the case of soil, the plant disease control component is applied to the soil surface, injected into the soil, or mixed into the soil; in the case of hydroponic culture solution, the plant disease control component is diluted in the hydroponic culture solution.