Structure for adjustable positioning and fixation of multi-organ biomimetic model and lesion

Abstract

An adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions includes: a body model with a recessed simulated space; a movable cavity slidably disposed in the simulated space, the movable cavity having a recessed accommodating space; a drive unit disposed in the simulated space and connected to the movable cavity; a control unit electrically connected to the drive unit; an organ bionic prosthesis comprising multiple heterogeneous prostheses with a density gradient distribution; at least one adjustable positioning element with a reset elasticity connected between the organ bionic prosthesis and the movable cavity, simulating suspension and fixing the organ bionic prosthesis within the accommodating space; the control unit controls the drive unit, the drive unit drives the movable cavity to move, the adjustable positioning element provides the organ bionic prosthesis with a support strength, and the organ bionic prosthesis simulates multi-dimensional rhythmic motion under the support strength by the movement of the movable cavity and the suspension support of the adjustable positioning element.

Claims

1. An adjustable positioning and fixing structure for multi-organ bionic prostheses and lesions, comprising: a body model with a recessed simulated space; a movable cavity slidably disposed in the simulated space, the movable cavity having a recessed receiving space; a drive unit disposed in the simulated space and connected to the movable cavity; a control unit electrically connected to the drive unit; an organ bionic prosthesis comprising a plurality of heterogeneous prostheses having a density gradient distribution; at least one adjustable positioning element having a reset elasticity, connected between the organ bionic prosthesis and the movable cavity, simulating suspension and fixing the organ bionic prosthesis within the receiving space; the control unit controls the drive unit, the drive unit drives the movable cavity to move, the adjustable positioning element provides the organ bionic prosthesis with a support strength, the organ bionic prosthesis simulating multi-dimensional rhythmic movements under the support strength by the movement of the movable cavity and the suspension support of the adjustable positioning element.

2. The adjustable positioning and fixation structure for multi-organ biomimetic prostheses and lesions as described in claim 1, wherein the organ biomimetic prosthesis comprises: a normal tissue prosthesis, which is formed by a hydrophilic gel in the shape of an organ; a first rigid prosthesis, which is formed by the hydrophilic gel in the shape of a nodule, tissue, or cyst, the first rigid prosthesis being encapsulated within the normal tissue prosthesis, the first rigid prosthesis having a first hardness; a second rigid prosthesis, which is formed by the hydrophilic gel in the shape of a nodule, tissue, or cyst, the second rigid prosthesis being encapsulated within the normal tissue prosthesis, the second rigid prosthesis having a second hardness greater than the first hardness; a lesion prosthesis, which is formed by the hydrophilic gel in the shape of a tumor, the lesion prosthesis being encapsulated within the normal tissue prosthesis, the lesion prosthesis having a third hardness; and an outer membrane prosthesis, which encapsulates or surrounds the normal tissue prosthesis, the outer membrane prosthesis having a fourth hardness.

3. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 1, wherein, The adjustable positioning element is an elastic element, and at least one of the elastic elements can be replaced with other elastic elements with different elastic coefficients, thereby changing the support strength.

4. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 3, wherein, The bionic prosthesis of the organ is surrounded by a plurality of connectors, and the elastic element is connected to the aforementioned connectors, so that the bionic prosthesis of the organ is connected to the inner wall of the movable cavity via the aforementioned elastic element.

5. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 1, wherein, The drive unit is connected to the moving cavity via a universal joint.

6. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 2, wherein, The normal tissue prosthesis contains 60±4 parts by weight of polyvinyl alcohol (PVA), 600±5 parts by weight of glycerol (glucerol), and 1404±5 parts by weight of deionized water.

7. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 2, wherein, The outer membrane prosthesis contains 100 to 400 parts by weight of polyvinyl alcohol (PVA), 100 to 400 parts by weight of glycerol (glucerol), and 1600 to 1900 parts by weight of deionized water.

8. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 2, wherein, The first hardened compound comprises 70±5 parts by weight of polyvinyl alcohol (PVA), 600±5 parts by weight of glycerol, and 1404±5 parts by weight of deionized water.

9. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 2, wherein, The second hardened compound comprises 80±4 parts by weight of polyvinyl alcohol (PVA), 600±5 parts by weight of glycerol (glucerol), and 1404±5 parts by weight of deionized water.

10. The adjustable positioning and fixation structure for multi-organ bionic prostheses and lesions as described in claim 2, wherein, The lesion prosthesis contains 500±7 parts by weight of first deionized water, 50±7 parts by weight of sodium carbonate, 200±7 parts by weight of sodium polyacrylate, 200±7 parts by weight of crosslinking agent, 30±7 parts by weight of ammonium persulfate, 30±7 parts by weight of second deionized water, and 40±7 parts by weight of calcium acetate. The crosslinking agent is NN-methylenebisacrylamide or ethylene glycol dimethacrylate.

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