Methods for enhanced removal of impurities during protein a chromatography

TWI941087BActive Publication Date: 2026-10-01GENZYME CORP
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Patent Information

Application Number
TW114107063
Authority / Receiving Office
TW · TW
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-07-05
Filing Date
2018-12-21
Publication Date
2026-10-01
Estimated Expiration
2038-12-20

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Abstract

This article provides methods for purifying Fc-containing peptides (e.g., antibodies) via protein A chromatography; methods for using a washing solution containing benzoate and / or benzyl alcohol during protein A chromatography; and methods for conditioning the harvest with sodium benzoate prior to protein A chromatography.
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Citation Information

Patent Citations

  • Wash solution and method for affinity chromatography

    WO2012164046A1