Controllable particle size mechanism and controllable particle size atomizing device

Abstract

A controllable particle size atomizing mechanism and a controllable particle size atomizing device are disclosed for use with an atomizing unit. The controllable particle size atomizing mechanism includes a coating unit for coating the aerosol generated by the atomizing unit. The coating unit defines an internal aerosol space to form a controlled flow environment. The coating unit has at least one aerosol outlet communicating with the aerosol space. The at least one aerosol outlet is configured to discharge aerosol within a preset particle size range from the coating unit. The coating unit is configured such that the flow direction of aerosol condensing into droplets within the aerosol space differs from the flow direction of the aerosol discharged from the coating unit via the at least one aerosol outlet. The controllable particle size atomizing device includes an atomizing unit and a controllable particle size atomizing mechanism. The controllable particle size atomizing mechanism and controllable particle size atomizing device of the present invention allow the aerosol within the mechanism to form a preset particle size range before flowing out, achieving particle size control.

Description

Technical Field

[0001] This invention relates to an atomizing device, and more particularly to a controllable particle size mechanism for an atomizing device and an atomizing device having the aforementioned mechanism and controllable particle size. Prior Technology

[0002] Traditional nebulization devices rely on aerosol generating elements to produce aerosol, thus determining the aerosol particle size at the time of aerosol generation. For example, micro-mesh nebulizers use microporous plates to determine the aerosol particle size, while jet-type or ultrasonic nebulizers rely on impact patterns. This design results in uneven aerosol particle size distribution in existing nebulizers, or high costs associated with controlling the aerosol particle size.

[0003] Furthermore, in the process of generating aerosol, the particle size of existing technologies exists in a normal distribution pattern, resulting in an overall larger particle size of the emitted aerosol. This makes it impossible to further reduce the particle size of the aerosol produced by the device, and also makes it impossible to perform more effective deep lung treatment. Summary of the Invention

[0004] To address the problems of the prior art, the present invention proposes an Aerosol Size Control Core for an atomizing device, and an atomizing device having the aforementioned core that can control and produce smaller particle sizes.

[0005] To achieve the above and other objectives, the present invention proposes a controllable particle size mechanism for use with an atomizing unit, comprising: a coating unit for coating the aerosol generated by the atomizing unit, the coating unit defining an internal aerosol space to form a controlled flow environment, wherein the coating unit has at least one aerosol outlet communicating with the aerosol space, and the at least one aerosol outlet is configured to export aerosol of a preset particle size range in the aerosol space to the coating unit, and the coating unit is configured such that the flow direction of the aerosol condensed in the aerosol space is different from the flow direction of the aerosol exported from the coating unit via the at least one aerosol outlet.

[0006] Optionally, the at least one aerosol outlet is located on the top, side, or bottom surface of the covering unit.

[0007] Optionally, it also includes a particle size screening structure disposed in the aerosol space, which is used to prevent aerosol particles larger than the preset particle size range from passing through the at least one aerosol outlet.

[0008] Optionally, the particle size screening structure includes one of a guide surface, a baffle, or a micromesh.

[0009] Optionally, the device also includes a liquid guide section disposed on the covering unit. The liquid guide section includes at least one inclined surface, groove, rib, or curved surface, or any combination thereof. The liquid guide section is used to allow the aerosol condensed in the aerosol space to flow back to the liquid supply area.

[0010] Optionally, the coating unit has multiple aerosol outlets, and the number of the particle size screening structure and the liquid guide section is the same as the number of the multiple aerosol outlets, so that the multiple aerosol outlets, the particle size screening structure and the liquid guide section are configured in a one-to-one correspondence.

[0011] The present invention also provides an atomizing device capable of controlling and producing smaller particle sizes, comprising: an atomizing unit for atomizing liquid to produce a mist; and a mechanism according to the above-described controllable particle size, wherein the mist space accommodates or is adjacent to the atomizing unit to cover the mist produced by the atomizing unit.

[0012] Optionally, the atomizing unit is one of a pneumatic jet atomizing module, an ultrasonic atomizing module, or a micro-mesh atomizing module.

[0013] Optionally, the atomizing unit is a pneumatic jet atomizing module, and the inside of the covering unit is provided with an impact element, which is configured to generate primary atomized mist by being impacted by the high-speed airflow generated by the atomizing unit.

[0014] Optionally, the coating unit also has a mounting portion and is aligned with the nozzle of the atomizing unit. The impact element is mounted on the coating unit via the mounting portion in a detachable or fixed manner.

[0015] Optionally, the nozzle of the atomizing unit and the coating unit are integrally formed, and the relative positions of the nozzle and the coating unit remain fixed.

[0016] Therefore, the controllable particle size mechanism of the present invention utilizes the internal structural design of the mechanism to allow the aerosol within the mechanism to form a preset particle size range before flowing out, and allows the droplets condensed from the aerosol with larger particle size (outside the preset particle size range) to flow back to the original liquid supply area through the liquid guide section, where they can be re-atomized. This design allows for particle size control without altering the original structure of the atomizing device, thereby reducing the development time and cost of the atomizing device. The controllable particle size mechanism of the present invention can also be combined with an atomizing unit to form a controllable particle size atomizing device. Furthermore, the flow direction of the aerosol within the preset particle size range leaving the aerosol outlet differs from the flow direction of the condensed droplets. This also improves upon the situation in the prior art where the produced aerosol and the returned liquid flow out from the same outlet, resulting in large droplets remaining along the aerosol path (medicine cup, breathing tube, mask, mouthpiece) and failing to be fully atomized, causing medication residue and waste. Simple Explanation of the Diagram

[0017] Figure 1 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the first embodiment of the present invention. Figure 2 is a three-dimensional schematic diagram of Figure 1 from another perspective. Figure 3 is a cross-sectional schematic diagram of the controllable particle size mechanism according to the first embodiment of the present invention. Figure 4 is an exploded view of the atomizing device with controllable particle size according to the first embodiment of the present invention. Figure 5 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the second embodiment of the present invention. Figure 6 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the third embodiment of the present invention. Figure 7 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the fourth embodiment of the present invention. Figure 8 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the fifth embodiment of the present invention. Figure 9 is a three-dimensional schematic diagram of the controllable particle size mechanism according to the sixth embodiment of the present invention. Figure 10 shows the drug sedimentation distribution of other brands of nebulizers compared to that of the present invention. Figure 11 is a drug particle size distribution diagram of an atomizing device using the controllable particle size mechanism of the present invention. Implementation

[0018] To fully understand the present invention, a detailed description is provided below with reference to the specific embodiments and accompanying drawings. Those skilled in the art can understand the purpose, features, and effects of the present invention from the content disclosed in this specification. It should be noted that the present invention can be implemented or applied through other different specific embodiments, and various details in this specification can also be modified and changed based on different viewpoints and applications without departing from the spirit of the present invention. The following embodiments will further describe the relevant technical content of the present invention in detail, but the disclosed content is not intended to limit the scope of the patent application of the present invention. The description is as follows:

[0019] As shown in Figures 1 to 4, the controllable particle size mechanism of the first embodiment of the present invention is used in conjunction with the atomizing unit 4 to generate aerosol within a preset particle size range. The controllable particle size mechanism includes a coating unit 1.

[0020] The covering unit 1 is used to cover the aerosol generated by the atomizing unit 4, and the covering unit 1 defines an internal aerosol space S to form a controlled flow environment. Referring to FIG1, the covering unit 1 in this embodiment is in the form of a cover, having a top wall 11 and a side wall 12. The top wall 11 and the side wall 12 define the aforementioned aerosol space S to accommodate at least a portion of the atomizing unit 4. The atomizing unit 4 can enter through the assembly port 14 of the covering unit 1 and be assembled with the covering unit 1. However, the present invention is not limited thereto, and the specific structure of the covering unit 1 can be adjusted as needed. Any element that can cover the aerosol generated by the atomizing unit 4 and have an aerosol space S can be used as the covering unit 1 of the present invention.

[0021] The coating unit 1 has at least one aerosol outlet 13, which communicates with the aerosol space S and is configured to export aerosol within a preset particle size range from the aerosol space S to the coating unit 1. Specifically, in this embodiment, the top wall 11 has multiple aerosol outlets 13, allowing aerosol with smaller particle sizes falling within a preset particle size range (e.g., less than or equal to 3 micrometers) formed from liquid atomization to pass upwards. Other aerosols with larger particle sizes cannot pass through the aerosol outlets 13 and eventually condense in the aerosol space S, flowing back along the internal wall of the coating unit 1. In other words, only aerosols with sufficiently small particle sizes can pass through the controllable particle size mechanism and be ejected upwards as atomized aerosol. By adjusting parameters such as the size, shape, height, position, number, and distribution of the aerosol outlets 13, the preset particle size range can be determined, thus ensuring that only small-particle-size aerosols with better therapeutic effects and the ability to penetrate deep into the lungs are exported from the coating unit 1 and reach the depths of the lungs. The remaining large-diameter aerosols that do not meet the preset particle size range condense into droplets and flow back to the liquid supply area, which is usually a medicine cup containing liquid medicine. These reflowing droplets can continue to be atomized by the atomizing unit 4, and will not adhere to the cup wall, thus avoiding waste of medicine residue.

[0022] The coating unit 1 of the present invention is further configured such that the flow direction of the aerosol condensing into droplets in the aerosol space S is different from the flow direction of the aerosol exiting the coating unit 1 via at least one aerosol outlet 13. As shown in Figures 1 to 3, aerosol within a preset particle size range is light enough to flow upward through the aerosol outlet 13, while the remaining aerosol outside the preset particle size range condenses into droplets and flows back along the interior of the coating unit 1 (e.g., the sidewall 12). The aerosol within the preset particle size range does not flow in the same direction as the condensed droplets. Therefore, a particle size limitation is substantially imposed.

[0023] In this embodiment, the aerosol outlet 13 is located on the top surface (top wall 11) of the coating unit 1, and the condensed droplets flow to the assembly port 14 (from which they can leave the coating unit 1, or remain in a liquid state in the aerosol space S awaiting further atomization). However, the present invention is not limited to this; the aerosol outlet 13 may also be located on the side or bottom surface of the coating unit 1, and the flow direction of the condensed droplets may be designed differently from the flow direction of the aerosol passing through the aerosol outlet 13.

[0024] Further, as shown in Figures 2 and 3, in this embodiment, the controllable particle size mechanism also includes a particle size screening structure 2. The particle size screening structure 2 is disposed in the aerosol space S and is used to prevent aerosol particles larger than a preset particle size range from passing through the aerosol outlet 13. The particle size screening structure 2 includes, for example, a guide surface, a baffle, or a micromesh. Any structure that allows small-sized aerosol particles to pass through and blocks large-sized aerosol particles from passing through the aerosol outlet 13 can be used as the particle size screening structure 2 of this invention.

[0025] In this embodiment, the particle size screening structure 2 serves as a guide surface. Only aerosol particles with sufficiently small diameters can bypass the particle size screening structure 2 and exit the coating unit 1 through the aerosol outlet 13. Aerosol particles with larger diameters that cannot bypass the particle size screening structure 2 remain inside the coating unit 1. Therefore, the particle size screening structure 2 filters or retains aerosol particles larger than a preset particle size range to improve the uniformity and efficiency of the output aerosol particle size. Furthermore, by adjusting the length, shape, and opening size of the particle size screening structure 2, the preset particle size range can be adjusted to further limit the particle size of the aerosol output by the controllable particle size mechanism.

[0026] Further, as shown in Figure 3, in this embodiment, the controllable particle size mechanism also includes a liquid guide section 3, disposed in the coating unit 1. The liquid guide section 3 includes at least one inclined surface, groove, rib, or curved surface, or any combination thereof. The liquid guide section 3 is used to allow the aerosol (droplets) condensed in the aerosol space S to flow back to the liquid supply area for re-atomization by gravity or inertia. The liquid guide section 3 can be a structure combined with the particle size screening structure 2, that is, the structure formed by the particle size screening structure 2 and the liquid guide section 3 has the dual purpose of "allowing aerosol with a particle size within a preset particle size range to pass through the aerosol outlet 13, filtering and retaining aerosol larger than the preset particle size range" and "allowing the droplets condensed in the aerosol space S to flow back".

[0027] Furthermore, as shown in Figures 2 and 3, in this embodiment, the coating unit 1 has multiple aerosol outlets 13, and the number of particle size screening structures 2 and liquid guide sections 3 is the same as the number of aerosol outlets 13, so that the multiple aerosol outlets 13, particle size screening structures 2, and liquid guide sections 3 are configured in a one-to-one correspondence. That is, each aerosol outlet 13 is provided with a set of particle size screening structures 2 and liquid guide sections 3 to form multiple sets of independent and parallel atomization paths, thereby improving the overall atomization efficiency and mist exhaust stability.

[0028] Furthermore, as shown in Figure 4, in this embodiment, the controllable particle size core is combined with the atomizing unit 4 to form an atomizing device with controllable particle size.

[0029] The atomizing unit 4 is used to atomize the liquid to produce an aerosol. The aerosol space S accommodates or is adjacent to the atomizing unit 4 to cover the aerosol produced by the atomizing unit 4. The atomizing unit 4 is, for example, one of a pneumatic jet atomizing module, an ultrasonic atomizing module, or a micro-mesh atomizing module. The present invention does not limit the type of atomizing unit 4.

[0030] Figure 4 shows an atomizing unit 4, exemplified by a pneumatic jet atomizing module. The atomizing unit 4 of this pneumatic jet atomizing module type includes a medicine cup 41, a venturi tube 42, and an impact element 43. The venturi tube 42 and its gas nozzle outlet 431 provide the power for the high-speed impact of the gas. The impact element 43 can be formed in various ways. In this embodiment, the impact element 43 is fixedly formed at one end of the venturi tube 42 and then assembled inside the covering unit 1. However, the invention is not limited to this; the impact element 43 can also be directly formed inside the covering unit 1, or the impact element 43 can be a separate component connected to the covering unit 1 and the venturi tube 42 through assembly. The assembly method, formation method, and specific shape and size of the impact element 43 can be appropriately varied as needed, and the invention is not limited to the implementation of the impact element and impact surface.

[0031] When the gas ejected from the nozzle outlet 431, carrying liquid, impacts the impact element 43 located inside the coating unit 1, it generates droplets of numerous sizes. Only droplets with sufficiently small particle sizes can bypass the particle size screening structure 2 and exit the atomizing device with controllable particle size of the present invention through the atomization outlet 13. In other words, the impact element 43 is configured to generate primary atomized atomized mist by being impacted by the high-speed airflow generated by the atomization unit 4.

[0032] Furthermore, in this embodiment, the atomizing device with controllable particle size also includes an output pipe 5. The output pipe 5 is connected to the aerosol outlet 13 to deliver aerosol with a preset particle size range from the aerosol outlet 13 to the human body.

[0033] Further, as shown in Figures 2 and 3, in this embodiment, the coating unit 1 also has a mounting portion 15, which is aligned with the impact element 43 of the atomizing unit 4. The impact element 43 is disposed on the coating unit 1 via the mounting portion 15 in a detachable or fixed manner. In this embodiment, the mounting portion 15 is, for example, a groove (mounting seat) whose shape matches that of the impact element 43. In other embodiments, the mounting portion 15 may also be, for example, a mounting hole, to accordingly mount the impact element 43.

[0034] Furthermore, as shown in Figure 9, in the sixth embodiment of the present invention, the nozzle outlet 431 of the atomizing unit 4 and the coating unit 1 are integrally formed, thereby keeping the relative positions of the nozzle outlet 431 and the coating unit 1 fixed. Therefore, there is no relative displacement between the two, which can improve the operational stability of the device and the consistency of atomization quality.

[0035] This invention's nebulizer uses a controllable particle size mechanism paired with a pneumatic jet nebulization module, producing an aerosol with a mass median aerodynamic diameter (MMAD) of less than 3 micrometers. In other words, half the mass of the aerosol is less than 3 micrometers. This allows most of the aerosol particles to penetrate deep into the respiratory tract, reaching the lungs, rather than remaining only in the mouth and upper respiratory tract. Therefore, it provides more effective nebulization therapy and reduces the burden of inhaling excessive medication.

[0036] The controllable particle size mechanism of this invention filters the primary atomized aerosol within the coating unit 1. Through the structural design of the coating unit 1, the primary atomized aerosol is divided into two parts: one part, containing a non-preset particle size, flows back to the liquid, while the other part, containing a preset particle size, leaves the coating unit 1 through the aerosol outlet 13. This mechanism prevents condensed droplets from adhering to other areas outside the coating unit 1, thus avoiding liquid recirculation and re-atomization (reducing drug delivery rate). Furthermore, the structural design within the coating unit 1 allows for control over the particle size and concentration of the atomized aerosol, improving upon existing atomization devices that suffer from excessively wide particle size distribution, excessive liquid residue, and intermittent or unstable atomization.

[0037] Furthermore, as shown in Figure 5, the present invention proposes a second embodiment of a controllable particle size mechanism, in which the impact element 43 is directly formed on the top wall 11. The remaining portion is hollowed out to form the aerosol outlet 13.

[0038] Furthermore, as shown in Figure 6, the present invention proposes a third embodiment of a controllable particle size mechanism, the main difference from the first embodiment being the shape and number of aerosol outlets 13, and the style of the particle size screening structure 2 and the liquid guiding section 3. In the third embodiment, the number of aerosol outlets 13 is six. Each aerosol outlet 13 in the third embodiment has a set of particle size screening structures 2 and liquid guiding sections 3.

[0039] Furthermore, as shown in Figure 7, the present invention proposes a fourth embodiment of a controllable particle size mechanism, the main difference of which is that the coating unit 1 has through holes 16, and each aerosol outlet 13 surrounds the through holes 16. The purpose of the through holes 16 is to allow for the installation and integration with the bottle body and impact element (external element) of an existing atomizing device to generate atomized droplets.

[0040] Furthermore, as shown in Figure 8, the present invention proposes a fifth embodiment of a controllable particle size mechanism, the main difference of which is that it has only a single aerosol outlet 13, and this aerosol outlet 13 also serves as the aforementioned through-hole 16. That is, the fifth embodiment of the controllable particle size mechanism is also intended for direct integration into existing atomizing devices, with the impact element (external element) directly disposed in the single aerosol outlet 13. The aerosol generated by the impact element bypasses the particle size screening structure 2 and passes through the aerosol outlet 13, thus achieving particle size screening and control. In the fifth embodiment, multiple sets of particle size screening structures 2 and liquid guide sections 3 are used together for a single aerosol outlet 13.

[0041] The above embodiments demonstrate that the controllable particle size mechanism and the controllable particle size atomizing device of the present invention can present diverse structures. The impact element 43 can be an internal element or integrated into existing atomizing device products (external element). The impact surface of the impact element 43 can be designed in different shapes, such as a plane, a concave surface, or a crossbar, to generate aerosol. By designing the size, shape, number, and placement of the aerosol outlet 13, the particle size, particle size concentration, and atomization rate of the aerosol can be controlled, thereby determining the preset particle size range.

[0042] Experimental verification

[0043] To verify that the controllable particle size mechanism and the controllable particle size atomizing device of the present invention are indeed superior to many existing atomizing devices, the present invention provides the following test report. The performance of commercially available jet small volume nebulization devices was tested in terms of aerosol particle size distribution after high-pressure gas atomization, atomization speed, and remaining medication in the medicine cup.

[0044] Test items:

[0045] 1. Test the following small spray cans

[0046] A. G Company Small-volume spray bottle

[0047] B. P Company Small-volume spray bottles

[0048] C. The atomization device of the present invention with controllable particle size

[0049] 2. Measure the particle sizing of the spray can according to the Annex D smoke density standard.

[0050] Test standard: Annex D (Test methods for particle sizing) of ISO 27427:2013.

[0051] Research conditions: In accordance with ISO standards, the room temperature was maintained at 23±2 ℃ and the relative humidity was 45-75%.

[0052] Research Instruments and Settings: Based on the Annex D smoke density standard, a next-generation impactor (MSP, Shoreview, Minnesota) was used. The operating flow rate was calibrated using a dry gas flow meter (TSI Instrument Inc. Shoreview, Minnesota, Model 4040) and was 15.0 ± 0.1 L / min. The collection stage consisted of 8 stages. After calibration experiments, the particle sizes of the collected aerosols were 14.10 μm, 8.61 μm, 5.39 μm, 3.30 μm, 2.08 μm, 1.36 μm, 0.98 μm, and <0.5 μm, respectively.

[0053] Water used for reagents: Research-grade double-filtered water

[0054] Trial reagent: 0.1% Salbutamol sulfate (Xindong Company)

[0055] Drug dosage analysis: The absorbance of the samples was measured using a UV-Vis Spectrophotometer (ThermoScitific Inc., Waltham, MA USA) at a wavelength of 276 nm. Before the experiment, a solution of the drug with a known concentration was prepared, placed in the spectrophotometer, and the absorbance was obtained. The relevant calculation formula was then derived to calculate the subsequent sample concentration.

[0056] Test program:

[0057] A. The suction flow rate of the impact sampler was confirmed to be 15.0 ± 10% L / min using a TSI flow meter.

[0058] B. 0.2% salbutamol, use a micropipette to draw 2.5 mL (5 mg) into the medicine cup.

[0059] C. 50 psig oxygen with TSI flow meter calibrated / confirmed flow rate setting.

[0060] D. Turn on the oxygen to the specified flow rate and start spraying.

[0061] E. Spray until no more aerosol is produced, and record the spraying time.

[0062] F. Disassemble the impactor, add secondary water to each stage to dissolve, and shake for two minutes to extract the drug.

[0063] G. Measure the absorbance of the extracted drug solution using a spectrophotometer, and calculate the drug dosage using the formula 'absorbance-concentration'.

[0064] H. Input the mass data of each sedimentation stage into a dedicated program to calculate the sedimentation drug distribution and obtain MMAD, geometric standard deviation (GSD), and the proportion of inhalable particles.

[0065] The test results are shown in Figure 10. Figure 10 is a comparison of the drug accumulation curves of the small-volume spray bottle from Company G, the small-volume spray bottle from Company P, and the nebulizer with controllable particle size mechanism of the present invention. Figure 11 is a drug particle size distribution diagram of the nebulizer using the controllable particle size mechanism of the present invention.

[0066] The test results show that the atomizing device using the controllable particle size mechanism of this invention produces droplet sizes significantly smaller than the control group (small-volume spray bottles from G Technology and P Company). Notably, over 96% of the atomized droplet sizes produced by the atomizing device using the controllable particle size mechanism of this invention are less than or equal to 1.36 μm. The test results above demonstrate that the controllable particle size mechanism of this invention has a significant effect on reducing the aerosol droplet size (from 5.03 μm to 1.54 μm) and increasing the number of droplets with the smallest particle size.

[0067] The present invention has been disclosed above with reference to embodiments. However, those skilled in the art should understand that these embodiments are merely illustrative of the invention and should not be construed as limiting its scope. It should be noted that all variations and substitutions equivalent to these embodiments should be considered within the scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the claims.

[0068] 1: Covering unit 11: Top Wall 12: Sidewall 13: Aerosol outlet 14: Assembly port 15: Installation Department 16: Through-hole 2: Particle size screening structure 3: Liquid guide section 4: Atomizing Unit 41: Medicine Cup 42: Venturi tube 43: Impact element 431: Nozzle outlet 5: Output tube S: Aerosol space

Claims

1. A controllable particle size mechanism for use with an atomizing unit, comprising: a coating unit for coating the aerosol produced by the atomizing unit, the coating unit having a top wall and a side wall defining an aerosol space to form a controlled flow environment; and a particle size filtering structure disposed on the top wall and extending into the aerosol space; wherein... The coating unit has at least one aerosol outlet communicating with the aerosol space. The particle size screening structure is used to prevent aerosol particles larger than a preset particle size range in the aerosol space from passing through the at least one aerosol outlet. The at least one aerosol outlet is configured to export aerosol particles within the preset particle size range from the coating unit. The coating unit is configured such that the flow direction of aerosol condensing into droplets in the aerosol space is different from the flow direction of aerosol exported from the coating unit via the at least one aerosol outlet. The particle size screening structure includes one of a guide surface, a baffle, or a micromesh.

2. The controllable particle size mechanism as described in claim 1, wherein the at least one aerosol outlet is disposed on a top surface, a side surface, or a bottom surface of the coating unit.

3. The controllable particle size mechanism as described in claim 1 further includes a liquid guide portion disposed in the coating unit, the liquid guide portion including at least one inclined surface, a groove, a rib or a curved surface, or any combination thereof, the liquid guide portion being used to allow the aerosol condensed in the aerosol space to flow back to a liquid supply area.

4. The controllable particle size mechanism as described in claim 1, wherein the coating unit has a plurality of aerosol outlets, the number of particle size screening structures and the number of liquid guides are the same as the number of the plurality of aerosol outlets, such that the plurality of aerosol outlets, the particle size screening structures and the liquid guides are configured in a one-to-one correspondence.

5. An atomizing device with controllable particle size, comprising: an atomizing unit for atomizing a liquid to produce an aerosol; and a mechanism with controllable particle size as described in any one of claims 1 to 4, wherein the aerosol space accommodates or is adjacent to the atomizing unit to cover the aerosol produced by the atomizing unit.

6. The atomizing device with controllable particle size as described in claim 5, wherein the atomizing unit is one of a pneumatic jet atomizing module, an ultrasonic atomizing module, or a micro-mesh atomizing module.

7. The atomizing device with controllable particle size as described in claim 6, wherein the atomizing unit is a pneumatic jet atomizing module, and an impact element is disposed inside the coating unit, the impact element being configured to generate primary atomized mist by being impacted by the high-speed airflow generated by the atomizing unit.

8. The atomizing device with controllable particle size as described in claim 7, wherein the coating unit further has a mounting portion and is aligned with the nozzle of the atomizing unit, and the impact element is disposed on the coating unit via the mounting portion in a detachable or fixed manner.

9. The atomizing device with controllable particle size as described in claim 6, wherein a nozzle of the atomizing unit and the coating unit are integrally formed, and the relative positions of the nozzle and the coating unit remain fixed.

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