Use of radish extract in the preparation of compositions for the protection and / or prevention of hearing loss.

Abstract

The use of a radish extract in the preparation of a composition for protecting and / or preventing hearing loss, the composition containing an effective amount of the radish extract, which can be extracted from fresh or fermented white radish, and when the composition is administered to an individual, the radish extract, at a specific effective amount, effectively prevents and protects the individual's auditory hair cells from lesions, thereby providing the radish extract with a hearing-protecting effect.

Claims

1. Use of a radish extract for preparing a composition for protecting and / or preventing hearing loss, the composition containing an effective amount of the radish extract (Raphanus sativus var. longipinnatus), the composition being administered to an individual, the radish extract having protective and preventative effects on the auditory hair cells of the individual, wherein the radish extract is extracted from the root of a white radish, and the radish extract is selected from fermented white radish, the fermented white radish containing polyphenolic compounds at a content between 1772.45±25.54 μg GAE / gW, and the fermented white radish containing flavonoid compounds at a content between 493.04±14.05 μg CE / gW.

2. Use of the radish extract as claimed in claim 1 for the preparation of a composition for the protection and / or prevention of hearing loss, wherein the composition is applied topically to the individual, and the effective amount of the radish extract is between 0.01 and 20 mg / ml based on the individual's weight.

3. Use of the radish extract as described in claim 2 for the preparation of compositions for the protection and / or prevention of hearing loss, wherein when the radish extract is selected from fermented white radish, the effective amount of the radish extract is between 0.05 and 5 mg / ml, and the radish extract can prevent and protect the individual's auditory hair cells from lesions induced by neomycin or cisplatin.

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