Radiotherapy treatment plan evaluation and improvement
US12654031B2Active Publication Date: 2026-06-16RAYSEARCH LAB
Patent Information
- Authority / Receiving Office
- US · United States
- Patent Type
- Patents(United States)
- Current Assignee / Owner
- RAYSEARCH LAB
- Filing Date
- 2022-06-16
- Publication Date
- 2026-06-16
AI Technical Summary
⚠Technical Problem
Existing radiotherapy treatment plans lack comprehensive evaluation methods that consider multiple factors such as Linear Energy Transfer (LET) and track ends, beyond dose distribution, to accurately predict treatment effects on patients.
⚗Method used
A computer-based method that simulates treatment plans, analyzes multiple metrics like dose, LET, and track ends using multivariate analysis, and visualizes their relationships to determine plan quality, allowing for adjustments or delivery decisions.
🎯Benefits of technology
Enhances the evaluation of radiotherapy plans by considering interdependent metrics, improving treatment efficacy and reducing uncertainties, thereby optimizing treatment outcomes.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure US12654031-D00000_ABST
Abstract
A radiotherapy treatment plan may be evaluated based on a combination of two or more metrics, by the steps of simulating the result of delivery of the plan, obtaining values from the simulation for at least a first and a second metric, performing a multivariate analysis of the values and determining a quality of the plan based on the result of the multivariate analysis. The metrics may include at least one of dose, LET, track ends, RBE, alpha / beta ratio and statistical uncertainty of the plan.
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