Molecular target in cancer
FRET-based assays enable the identification of small molecule inhibitors of MSI2-RNA interactions, addressing treatment resistance in MSI2-related cancers and offering promising anti-cancer therapies.
US12681009B2Active Publication Date: 2026-07-14RGT UNIV OF CALIFORNIA
Patent Information
- Authority / Receiving Office
- US · United States
- Patent Type
- Patents(United States)
- Current Assignee / Owner
- RGT UNIV OF CALIFORNIA
- Filing Date
- 2022-01-06
- Publication Date
- 2026-07-14
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Abstract
Disclosed are methods for identifying small molecule modulators of protein-RNA interactions that could potentially function as therapeutic agents in cancer treatment. Methods of identifying inhibitors of the RNA-binding functions of MSI2, as well as inhibitors identified thereof, are also disclosed.
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