Integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging

Abstract

The provided is a high-speed and high-stability integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging. The integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging includes a blister packaging machine and a blister boxing machine. The blister packaging machine is placed in a clean region, the blister boxing machine is placed in a non-clean region, and the clean region and the non-clean region are isolated by a partition wall. An isolation conveying device is provided between the blister packaging machine and the blister boxing machine. The isolation conveying device extends from the clean region through the partition wall to the non-clean region. A section of conveying path, in the clean region, of the isolation conveying device is located in an isolation sealing chamber. The isolation sealing chamber is provided with a feeding opening located in the clean region.

Description

CROSS-REFERENCE TO THE RELATED APPLICATIONS

[0001] This application is a continuation application of International Application No. PCT / CN2025 / 088387, filed on March 27, 2025, which is based upon and claims priority to Chinese Patent Application No. 202510376256.0, filed on March 27, 2025, the entire contents of which are incorporated herein by reference.TECHNICAL FIELD

[0002] The present invention relates to a pharmaceutical packaging machine, particularly to an integrated blister plate packaging and boxing machine.BACKGROUND

[0003] The production process of pharmaceutical packaging must meet relevant environmental production control requirements. In the existing production process, the blister packaging machine is typically located in the clean region, and the blister boxing machine is located in the non-clean region. A partition wall is provided between the clean region and the non-clean region to form an isolated production environment for the blister to boxing process of solid preparations. Due to the limitations of the production process, the mechanical actuation moving parts located in the non-clean region are not allowed to operate within the clean region, so as to prevent the mechanical movement from circulating between the clean region and the non-clean region and avoid causing bacteria, microorganisms or other contaminants to pollute and damage the production environment of the clean region. At present, the existing linked packaging process of the blister packaging machine and the blister boxing machine that are separated by a partition wall can be roughly divided into two methods: one is that the conveyor belt performs jointing, mechanical conveying and transferring of the blister medicine plates at the partition wall; and the other is that a fixed chute with a height difference is mounted at the partition wall, and the blister medicine plates located in the clean region are slid and transferred by inertial limiting sliding. The above two types of conveying and transferring devices currently present two different characteristics. When the conveyor belt is used to transfer the blister medicine plates, there is a friction slipping phenomenon, and the blister medicine plates cannot be precisely positioned and arranged, thus bringing the difficulty to the subsequent robot integrated transfer to the high-speed boxing process. When the unpowered inertial limiting sliding transfer method is adopted, transverse partition plates need to be set between the blister medicine plates to limit the sliding of the blister medicine plates. The setting of the transverse partition plates limits the multi-channel flexible output characteristics of the blister packaging machine, which creates a significant challenge to rapid product changeover. Moreover, since the air pressure in the clean region is significantly greater than an air pressure in the non-clean region, when the blister medicine plates slide through the partition wall by inertia, they are easily disturbed by the high-pressure air discharged from the clean region to the non-clean region. As a result, the blister medicine plates are prone to floating, deflection, jamming and other situations that affect the normal production rhythm, thereby creating substantial difficulty in achieving high-speed synchronous production from blister packaging to boxing packaging.SUMMARY

[0004] In view of the deficiencies of the prior art, the present invention innovatively provides a high-speed and high-stability integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging.

[0005] The integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging includes a blister packaging machine and a blister boxing machine. The blister packaging machine is placed in a clean region, the blister boxing machine is placed in a non-clean region, and the clean region and the non-clean region are isolated by a partition wall. An isolation conveying device is provided between the blister packaging machine and the blister boxing machine. The isolation conveying device extends from the clean region through the partition wall to the non-clean region. A section of conveying path, in the clean region, of the isolation conveying device is located in an isolation sealing chamber. The isolation sealing chamber is provided with a feeding opening located in the clean region, and the isolation sealing chamber is provided with a discharging port located in the non-clean region or at a junction of the clean region and the non-clean region. The isolation conveying device comes out from the discharging port of the isolation sealing chamber. The feeding opening of the isolation sealing chamber is located at a top of the isolation sealing chamber. A blister suction and placement manipulator is provided in the clean region. The blister suction and placement manipulator transfers blister plates cut by the blister packaging machine to the feeding opening of the isolation sealing chamber and places the blister plates on the isolation conveying device.

[0006] An air pressure in the clean region is greater than an air pressure in the non-clean region.

[0007] A vision detector and an elimination conveying mechanism are provided in the clean region. The vision detector is electrically connected to a control center, and the control center is electrically connected to the blister suction and placement manipulator. When the vision detector detects material missing inside the blister plate, the control center can control the blister suction and placement manipulator to send the blister plate onto the elimination conveying mechanism.

[0008] An elimination confirming detector is provided between the blister suction and placement manipulator and the elimination conveying mechanism. The elimination confirming detector is electrically connected to the control center, and the control center can control the blister suction and placement manipulator to send the blister plates to the isolation conveying device.

[0009] A suction confirming detector is provided above the blister suction and placement manipulator. The suction confirming detector is electrically connected to the control center, and the control center can control the blister packaging machine to stop.

[0010] The blister suction and placement manipulator includes a rotating disc and three loading suction nozzle units. The loading suction nozzle unit includes a suction and release nozzle, and a motion trajectory of the suction and release nozzle has four outermost points in up, down, left, and right directions. A left outermost point is located at a discharge end of the blister packaging machine. An upper outermost point is located below the suction confirming detector. A right outermost point is located above the elimination conveying mechanism. A lower outermost point is located inside the feeding opening of the isolation sealing chamber.

[0011] A plate missing detector, a blister plate material library, and a blister replenishment manipulator are provided in the non-clean region. The plate missing detector is located above the isolation conveying device and is electrically connected to the control center. The control center is electrically connected to the blister replenishment manipulator. When the plate missing detector detects plate missing on the isolation conveying device, the control center can control the blister replenishment manipulator to suck a blister plate from the blister plate material library and place the blister plate onto a material missing position of the isolation conveying device.

[0012] The blister replenishment manipulator includes a rotating disc and two replenishment suction nozzle units, and the replenishment suction nozzle unit includes a replenishment suction nozzle. A motion trajectory of the replenishment suction nozzle has three outermost points, where one of the outermost points sucks a blister plate from the blister plate material library, and another outermost point places the blister plate on the isolation conveying device.

[0013] The isolation conveying device includes a mounting base, a transmission belt, a pulley, and a plurality of conveying ribs. The transmission belt is wound around the pulley. There are two transmission belts on left and right, and two ends of the conveying rib are respectively connected to the two transmission belts on the left and right. The plurality of conveying ribs are equally connected to the transmission belts. A support platform is provided between the two transmission belts. The conveying rib performs a pushing action above the support platform. A groove extending along a conveying direction is formed on a surface of the support platform. A protrusion is formed at a bottom of the conveying rib. The protrusion of the conveying rib extends downward into the groove of the support platform.

[0014] Supporting wheels are connected to both ends of the conveying rib. The mounting base is provided with a lower support surface, the lower support surface is located below the transmission belt, and the supporting wheel at a lower part acts on the lower support surface. The mounting base is provided with an upper support surface, the upper support surface is located on an outside of the transmission belt, and the supporting wheel at an upper part acts on the upper support surface.

[0015] According to the integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging provided by the present invention, the isolation sealing chamber is provided in the clean region, and the isolation conveying device is provided in the isolation sealing chamber, forming a partitioned isolation conveying transfer of the blister medicine plate between the clean region and the non-clean region. This conveying method not only solves the problem of mutual cross-linking between the non-clean region and the clean region caused by the mechanical motion cycle, but also makes the conveying of the blister plate more stable.BRIEF DESCRIPTION OF THE DRAWINGS

[0016] FIG. 1 is a front view of an integrated blister packaging and boxing machine.

[0017] FIG. 2 is a perspective view of an isolation partition conveying system.

[0018] FIG. 3 is a front view of the isolation partition conveying system.

[0019] FIG. 4 is a perspective view of an isolation conveying device.

[0020] FIG. 5 is a schematic diagram showing a part of FIG. 4.

[0021] FIG. 6 is a perspective view of a conveying rib.

[0022] FIG. 7 is a side view of the isolation conveying device.

[0023] FIG. 8 is a partially enlarged view of position E in FIG. 7.

[0024] FIG. 9 is a partially enlarged view of position F in FIG. 7.

[0025] FIG. 10 is a structural schematic diagram of a blister suction and placement manipulator.

[0026] FIG. 11 is a structural schematic diagram of a blister replenishment manipulator.DETAILED DESCRIPTION OF THE EMBODIMENTS

[0027] As shown in FIG. 1, the integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging includes the blister packaging machine 1 and the blister boxing machine 2. The blister packaging machine 1 is used for the inner packaging of blister plates, specifically, to complete blister forming, capsule filling (or granular drug filling), as well as heat sealing and cutting of the blister plate. The blister packaging machine 1 is the prior art (for example, the patent with the publication number: CN114671091A). The blister boxing machine 2 is used for the outer packaging of blister plates, specifically, to push the cut blister plates together with the drug instructions into paper boxes. The blister boxing machine 2 is also the prior art (for example, the patent with the publication number: CN111114893A).

[0028] As shown in FIGS. 1 and 2, in order to meet the relevant environmental production control requirements, the blister packaging machine 1 is placed in a clean region A, and the blister boxing machine 2 is placed in a non-clean region B. The clean region A and the non-clean region B are isolated by the partition wall 4. It is worth mentioning that the clean region A is enclosed by a glass exterior wall (Certainly, it can also be enclosed by other plate materials). The non-clean region B can be enclosed by a glass exterior wall or not provided with an outer glass enclosure. The clean region A is a closed structure and is strictly prohibited from being opened, which has higher requirements for the bacterial content index in the air, to ensure that no bacteria is involved when capsules are filled in the blister plates, so as to meet the international hygiene standards for drug packaging.

[0029] In order to transfer the blister plates cut by the cutting unit 10 of the blister packaging machine 1 to the blister boxing machine 2, that is, to transfer the blister plates from the clean region A to the non-clean region B while preventing the non-clean region B from contaminating the clean region A, as shown in FIGS. 2 and 3, the present invention provides the isolation conveying device 3 between the blister packaging machine 1 and the blister boxing machine 2. The isolation conveying device 3 extends from the clean region A through the partition wall 4 to the non-clean region B. A section of conveying path, in the clean region A, of the isolation conveying device 3 is located in the isolation sealing chamber 7 (the isolation sealing chamber 7 is assembled from metal plates, glass plates or other various plate materials). The isolation sealing chamber 7 is provided with the feeding opening 70 located in the clean region A (the cut blister plates enter the isolation conveying device 3 through the feeding opening 70), and the isolation sealing chamber 7 is provided with the discharging port 71 located in the non-clean region B or at the junction of the clean region A and the non-clean region B. The isolation conveying device 3 comes out from the discharging port 71 of the isolation sealing chamber 7, and the feeding opening 70 of the isolation sealing chamber 7 is located at the top of the isolation sealing chamber 7. As shown in FIG. 2, the blister suction and placement manipulator 5 is provided in the clean region A. The blister suction and placement manipulator 5 can transfer the blister plates cut by the blister packaging machine 1 to the feeding opening 70 of the isolation sealing chamber 7 and place the blister plates on the isolation conveying device 3.

[0030] During operation, the blister suction and placement manipulator 5 sucks the blister plates cut by the cutting unit 10. Through movement, the blister plates pass through the feeding opening 70 of the isolation sealing chamber 7 and are transferred onto the isolation conveying device 3 (the feeding opening 70 of the isolation sealing chamber 7 is located at the top of the isolation sealing chamber 2, which is conducive to the blister suction and placement manipulator 5 sucking and placing the blister plates on the isolation conveying device 3). In this way, the blister plates enter the isolation sealing chamber 7. The isolation conveying device 3 conveys the blister plates forward and comes out from the discharging port 71 of the isolation sealing chamber 7 to continuously move forward. The characteristic of the isolation partition conveying system in this structure is that the non-clean region B extends into the clean region A through the isolation sealing chamber 7, that is, the isolation sealing chamber 7 constitutes a part of the non-clean region B. The non-clean region B and the clean region A are only communicated through the feeding opening 70 of the isolation sealing chamber 7, and the area of the feeding opening 70 can be made significantly small to reduce the contamination of the non-clean region B to the clean region A. At the same time, the air pressure in the clean region A can be increased to make the air pressure in the clean region A greater than the air pressure in the non-clean region B, so that the air in the clean region A can only enter from the feeding opening 70 of the isolation sealing chamber 7 and exit from the discharging port 71 of the isolation sealing chamber 7. In this way, the air in the non-clean region B cannot enter the clean region A through the feeding opening 70 of the isolation sealing chamber 7, thereby preventing the contamination to the clean region A and ensuring that the blister packaging machine 1 performs packaging in a sterile environment.

[0031] It is worth mentioning here that the discharging port 71 of the isolation sealing chamber 7 can be located in the non-clean region B. In this case, the isolation sealing chamber 7 needs to extend through the partition wall 4 to the right non-clean region B (the outer wall of the isolation sealing chamber 7 forms a seal with the partition wall 4 to prevent the air in the non-clean region B from entering the clean region A through a gap. However, due to the existence of air pressure, a little gap is not a problem). The structure in which the discharging port 71 is in the non-clean region B increases the length of the isolation sealing chamber 7. The isolation sealing chamber 7 can better guide the blister plates to move forward. The air pressure in the isolation sealing chamber 7 gradually decreases forward, making the blister plates more stable when exiting from the discharging port 71, thus being more conducive to the stable conveying of the blister plates. The discharging port 71 of the isolation sealing chamber 7 can also be located at the junction of the clean region A and the non-clean region B, that is, the discharging port 71 of the isolation sealing chamber 7 is located at the partition wall 4 (the discharging port 71 of the isolation sealing chamber 7 forms a seal with the partition wall 4 to prevent the air in the non-clean region B from entering the clean region A through a gap. However, due to the existence of air pressure, a little gap is not a problem). Both modes can be implemented.

[0032] As shown in FIG. 3, a vision detector and the elimination conveying mechanism 6 are provided in the clean region A (the vision detector is the prior art and is not shown in the figure). The vision detector is electrically connected to a control center, and the control center is electrically connected to the blister suction and placement manipulator 5. When the vision detector detects material missing inside the blister plate (there is no capsule or drug particles filled in the blister plate), the control center can control the blister suction and placement manipulator 5 to send the blister plates onto the elimination conveying mechanism 6. The elimination conveying mechanism 6 includes a conveyor belt, and the unqualified blister plates are conveyed to the collection box 72 through the conveyor belt for collection.

[0033] As shown in FIG. 3, the elimination confirming detector 60 is further provided between the blister suction and placement manipulator 5 and the elimination conveying mechanism 6. The elimination confirming detector 60 is electrically connected to the control center, and the control center can control the blister suction and placement manipulator 5 to send the blister plates to the isolation conveying device 3. When the elimination confirming detector 60 detects that the unqualified blister plate on the blister suction and placement manipulator 5 is not present (that is, the unqualified blister plate is already placed on the elimination conveying mechanism 6), the control center controls the blister suction and placement manipulator 5 to send the remaining normal blister plates to the isolation conveying device 3.

[0034] As shown in FIG. 3, the suction confirming detector 50 is provided above the blister suction and placement manipulator 5. The suction confirming detector 50 is electrically connected to the control center, and the control center can control the blister packaging machine 1 to stop. When the suction confirming detector 50 detects that there is no blister plate on the blister suction and placement manipulator 5, it means that the blister suction and placement manipulator 5 has not sucked the blister plates cut by the cutting unit 10. At this time, the control center controls the blister packaging machine 1 to stop.

[0035] As shown in FIG. 10, the blister suction and placement manipulator 5 includes the rotating disc 52 and three loading suction nozzle units 51. The rotating disc 52 drives the three loading suction nozzle units 51 to rotate. Each loading suction nozzle unit 51 includes the nozzle support 511 and a plurality of suction and release nozzles 510. The plurality of suction and release nozzles 510 are mounted on the nozzle support 511. The nozzle support 511 can also be automatically adjusted so that the suction and release nozzles 510 face the four outermost points, and the plurality of suction and release nozzles 510 of each loading suction nozzle unit 51 has independent suction and release functions. This blister suction and placement manipulator 5 is the prior art, such as the invention patent applied by the applicant (publication number CN109436798B). The difference is that this patent has one loading suction nozzle unit with three rows of suction and release nozzles (three nozzles per row), while the present application has three loading suction nozzle units 51, and each loading suction nozzle unit 51 has one row of suction and release nozzles 510 (as shown in figure, there are six, used to suck three blister plates). The blister suction and placement manipulator 5 of the present application has a higher conveying efficiency due to the use of three loading suction nozzle units 51, which is more in line with the linkage requirements of the blister packaging machine and the high-speed blister boxing machine. In addition, each suction and release nozzle 510 of the blister suction and placement manipulator 5 has an independent suction and release function (which is controlled by the control center, where the control principle can refer to the patent with the publication number CN109436798B). For example, one of the suction and release nozzles 510 on one loading suction nozzle unit 51 can independently place the unqualified blister plate on the elimination conveying mechanism 6, and replenish a qualified blister plate on the isolation conveying device 3 in the subsequent process. Certainly, the blister suction and placement manipulator 5 can also adopt other structures of manipulators (including existing manipulators on the market) as long as the blister plates can be transferred.

[0036] As described above, the motion trajectory of the suction and release nozzle 510 (as shown by 5M in FIG. 10) has four outermost points in the up, down, left, and right directions. The suction and release nozzle 510 faces the outermost side when being at the four outermost points. The left outermost point is located at the discharge end of the blister packaging machine 1, that is, at the discharge position of the cutting unit 10, for sucking the cut blister plates. The upper outermost point is located below the suction confirming detector 50, which is convenient for detecting whether the suction and release nozzle 510 has sucked the blister plate. The right outermost point is located above the elimination conveying mechanism 6, for placing the unqualified blister plates on the elimination conveying mechanism 6. The lower outermost point is located inside the feeding opening 70 of the isolation sealing chamber 7, for placing the qualified blister plates on the isolation conveying device 3.

[0037] As described above, when the unqualified blister plate is not sent to the isolation conveying device 3, it is necessary to replenish the blister plate onto the material missing position of the isolation conveying device 3 in the subsequent process. Therefore, as shown in FIG. 3, the plate missing detector 80, the blister plate material library 9, and the blister replenishment manipulator 8 are provided in the non-clean region B. The plate missing detector 80 is located above the isolation conveying device 3 and is electrically connected to the control center. The control center is electrically connected to the blister replenishment manipulator 8. When the plate missing detector 80 detects the plate missing on the isolation conveying device 3, the control center controls the blister replenishment manipulator 8 to suck the blister plates from the blister plate material library 9 and place them onto the material missing position of the isolation conveying device 3.

[0038] As shown in FIG. 11, the blister replenishment manipulator 8 includes the rotating disc 82 and two replenishment suction nozzle units 81. The rotating disc 82 drives the replenishment suction nozzle units 81 to rotate. The replenishment suction nozzle unit 81 includes the replenishment suction nozzle base 811 and a plurality of replenishment suction nozzles 810 (the number is consistent with the number of the suction and release nozzles 510, as shown in FIG. 11, there are six), and the replenishment suction nozzle base 811 can also rotate by itself to make the replenishment suction nozzles 810 face three outermost points. The structure of the blister replenishment manipulator 8 is similar to the structure of the blister suction and placement manipulator 5, except that the replenishment suction nozzles 810 have the three outermost points.

[0039] As shown in FIG. 11, the motion trajectory of the replenishment suction nozzle 810 (as shown by 8M in FIG. 11) has three outermost points. One of the outermost points is used to suck a blister plate from the blister plate material library 9, and another outermost point places the blister plate on the isolation conveying device 3 for replenishment. In addition, each replenishment suction nozzle 810 of the blister replenishment manipulator 8 has an independent suction and release function (which is controlled by the control center, where the control principle can refer to the patent with the publication number CN109436798B). For example, one of the replenishment suction nozzles 810 on one replenishment suction nozzle unit 81 can independently place the blister plate onto the material missing position of the elimination conveying mechanism 6. Certainly, the blister replenishment manipulator 8 can also adopt other structures of manipulators (including existing manipulators on the market) as long as the blister plates can be transferred.

[0040] As shown in FIGS. 4 and 5, the isolation conveying device 3 includes the mounting base 30, the transmission belt 32, the pulley 34, and a plurality of conveying ribs 33. The transmission belt 32 is wound around the pulley 34. The pulley 34 is driven to rotate by a power source. The pulley 34 drives the transmission belt 32 to move and perform a cyclic motion. Certainly, the isolation conveying device 3 can also use an existing grate conveying device on the market. This existing grate conveying device also includes a grate conveyor belt, and an equal number of pushing sheets are provided on this grate conveyor belt.

[0041] As shown in FIG. 5, there are two transmission belts 32 on the left and right, and two ends of the conveying rib 33 are respectively connected to the two transmission belts 32 on the left and right (the left end of the conveying rib 33 is connected to the transmission belt 32 on the left, and the right end of the conveying rib 33 is connected to the transmission belt 32 on the right). The plurality of conveying ribs 33 are equally connected to the transmission belts 32. A spacing for placing the blister plates is formed between two adjacent conveying ribs 33. The support platform 35 is provided between the two transmission belts 32. The conveying rib 33 performs a pushing action above the support platform 35. During operation, the power source drives the pulley 34 to rotate. The pulley 34 drives the transmission belts 32 to move forward and perform a cyclic motion. Since the two ends of the conveying rib 33 are connected to the two transmission belts 32 on the left and right, the conveying rib 33 moves forward together and performs a cyclic motion. The blister suction and placement manipulator 5 sucks the blister plates and places them on the support platform 35, and the blister plates are located between two adjacent conveying ribs 33. As the conveying rib 33 moves forward, the conveying rib 33 pushes the blister plates forward. This structure eliminates the partitions between multiple channels and uses one conveying rib 33 to replace the existing multi-channel multi-pushing sheet structure, greatly reducing the manufacturing difficulty and cost. Moreover, no alignment adjustment is required, significantly reducing the difficulty of equipment installation and debugging.

[0042] Since the conveying rib 33 performs the pushing action above the support platform 35, a gap is inevitably formed between the conveying rib 33 and the support platform 35. If the blister plate P is twisted or deformed or too thin in thickness, it may cause the plate surface of the blister plate P to get stuck in the gap between the conveying rib 33 and the support platform 35, resulting in the blister plate possibly not being able to be sucked by the manipulator in the subsequent process. To solve this problem, as shown in FIG. 5, grooves 350 extending along the conveying direction are formed on the surface of the support platform 35. As shown in FIG. 6, the protrusions 331 are formed at the bottom of the conveying rib 33. As shown in FIGS. 7 and 8, the protrusions 331 of the conveying rib 33 extend downward into the grooves 350 of the support platform 35. In this way, the lower ends of the protrusions 331 of the conveying rib 33 are lower than the surface of the support platform 35, and the plate surfaces of the blister plates are clamped outside by the protrusions 331 of the conveying rib 33 and cannot enter between the conveying rib 33 and the support platform 35, thus ensuring that the blister plates can be sucked by the manipulator in the subsequent process.

[0043] If a plurality of rows of blister plates are conveyed at one time (as shown in FIG. 5, three rows are conveyed at one time), a plurality of grooves 350 are formed on the surface of the support platform 35. The distance between two adjacent grooves 350 is less than the length of the blister plate (the plurality of rows of blister plates are generally arranged in the length direction thereof. If the plurality of rows of blister plates are arranged in the width direction thereof, the distance between two adjacent grooves 350 is less than the width of the blister plate). A plurality of protrusions 331 are formed at the bottom of the conveying rib 33, with each protrusion 331 corresponding to one groove 350. In this way, all the blister plates avoid getting stuck between the conveying rib 33 and the support platform 35.

[0044] Since the conveying belt 32 is relatively long, in order to prevent the conveying belt 32 from sagging, as shown in FIGS. 7 and 9, the supporting wheels 330 are connected to both ends of the conveying rib 33. The mounting base 30 is provided with the lower support surface 311, and the lower support surface 311 is located below the transmission belt 32. The supporting wheels 330 at the lower part act on the lower support surface 311, that is, the supporting wheel 330 on the lower section of the transmission belt 32 acts on the lower support surface 311. The lower support surface 311 provides support for the supporting wheel 330. The supporting wheel 330 is connected to the transmission belt 32 through the conveying rib 33. In this way, the lower section of the transmission belt 32 can be prevented from sagging downward, ensuring the stability and running accuracy of the motion of the transmission belt 32.

[0045] Similarly, the mounting base 30 is provided with the upper support surface 310, and the upper support surface 310 is located on the outside of the transmission belt 32. The supporting wheel 330 at the upper part acts on the upper support surface 310, that is, the supporting wheel 330 on the upper section of the transmission belt 32 acts on the upper support surface 310. The upper support surface 310 provides support for the supporting wheel 330. The supporting wheel 330 is connected to the transmission belt 32 through the conveying rib 33. In this way, the upper section of the transmission belt 32 can be prevented from sagging downward, ensuring the stability and running accuracy of the motion of the transmission belt 32.

Claims

1. An integrated blister packaging and boxing machine with isolated and partitioned inner and outer packaging, comprising a blister packaging machine and a blister boxing machine; wherein the blister packaging machine is placed in a clean region, the blister boxing machine is placed in a non-clean region, and the clean region and the non-clean region are isolated by a partition wall; an isolation conveying device is provided between the blister packaging machine and the blister boxing machine; the isolation conveying device extends from the clean region through the partition wall to the non-clean region; a section of conveying path, in the clean region, of the isolation conveying device is located in an isolation sealing chamber;the isolation sealing chamber is provided with a feeding opening located in the clean region, and the isolation sealing chamber is provided with a discharging port located in the non-clean region or at a junction of the clean region and the non-clean region; the isolation conveying device comes out from the discharging port of the isolation sealing chamber; the feeding opening of the isolation sealing chamber is located at a top of the isolation sealing chamber; a blister suction and placement manipulator is provided in the clean region; and the blister suction and placement manipulator is allowed to transfer blister plates cut by the blister packaging machine to the feeding opening of the isolation sealing chamber and place the blister plates on the isolation conveying device.

2. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 1, wherein an air pressure in the clean region is greater than an air pressure in the non-clean region.

3. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 1, wherein a vision detector and an elimination conveying mechanism are provided in the clean region; the vision detector is electrically connected to a control center, and the control center is electrically connected to the blister suction and placement manipulator; and when the vision detector detects material missing inside the blister plate, the control center is allowed to control the blister suction and placement manipulator to send the blister plate onto the elimination conveying mechanism.

4. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 3, wherein an elimination confirming detector is provided between the blister suction and placement manipulator and the elimination conveying mechanism; and the elimination confirming detector is electrically connected to the control center, and the control center is allowed to control the blister suction and placement manipulator to send the blister plates to the isolation conveying device.

5. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 4, wherein a suction confirming detector is provided above the blister suction and placement manipulator; and the suction confirming detector is electrically connected to the control center, and the control center is allowed to control the blister packaging machine to stop.

6. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 5, wherein the blister suction and placement manipulator comprises a rotating disc and three loading suction nozzle units; the loading suction nozzle unit comprises a suction and release nozzle, and a motion trajectory of the suction and release nozzle has four outermost points in up, down, left, and right directions; a left outermost point is located at a discharge end of the blister packaging machine; an upper outermost point is located below the suction confirming detector; a right outermost point is located above the elimination conveying mechanism; and a lower outermost point is located inside the feeding opening of the isolation sealing chamber.

7. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 3, wherein a plate missing detector, a blister plate material library, and a blister replenishment manipulator are provided in the non-clean region; the plate missing detector is located above the isolation conveying device and is electrically connected to the control center; the control center is electrically connected to the blister replenishment manipulator; and when the plate missing detector detects plate missing on the isolation conveying device, the control center is allowed to control the blister replenishment manipulator to suck a blister plate from the blister plate material library and place the blister plate onto a material missing position of the isolation conveying device.

8. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 7, wherein the blister replenishment manipulator comprises a rotating disc and two replenishment suction nozzle units, and the replenishment suction nozzle unit comprises a replenishment suction nozzle; and a motion trajectory of the replenishment suction nozzle has three outermost points, wherein a first one of the three outermost points sucks a blister plate from the blister plate material library, and a second one of the three outermost points places the blister plate on the isolation conveying device.

9. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 1, wherein the isolation conveying device comprises a mounting base, a transmission belt, a pulley, and a plurality of conveying ribs; the transmission belt is wound around the pulley; there are two transmission belts on left and right, and two ends of the conveying rib are respectively connected to the two transmission belts on the left and right; the plurality of conveying ribs are equally connected to the two transmission belts;a support platform is provided between the two transmission belts; the conveying rib performs a pushing action above the support platform; a groove extending along a conveying direction is formed on a surface of the support platform; a protrusion is formed at a bottom of the conveying rib; and the protrusion of the conveying rib extends downward into the groove of the support platform.

10. The integrated blister packaging and boxing machine with the isolated and partitioned inner and outer packaging according to claim 9, wherein supporting wheels are connected to both ends of the conveying rib; the mounting base is provided with a lower support surface, the lower support surface is located below the transmission belt, and the supporting wheel at a lower part acts on the lower support surface; and the mounting base is provided with an upper support surface, the upper support surface is located on an outside of the transmission belt, and the supporting wheel at an upper part acts on the upper support surface.

Images