COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

Description

THIS DESCRIPTION PRESENTS CHEMICAL ENTITIES (FOR EXAMPLE, A COMPOUND OR A SALT AND / OR HYDRATE, AND / OR COCRYSTAL, AND / OR PHARMACEUTICALLY ACCEPTABLE DRUG COMBINATION OF THE COMPOUND) THAT INHIBIT (FOR EXAMPLE, ANTAGONIZE) THE INTERFERON GENE STIMULATOR (STING). These chemical entities are useful, for example, for the treatment of a condition, disease, or disorder in which increased (e.g., excessive) activation of Sting (e.g., Sting signaling) contributes to the pathology and / or symptoms and / or progression of the condition, disease, or disorder (e.g., cancer) in a subject (e.g., a human being). This description also presents compositions containing these entities, as well as methods for using and manufacturing them.