COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING'S ACTIVITY

Description

THIS DISCLOSURE PRESENTS CHEMICAL ENTITIES (FOR EXAMPLE, A PHARMACEUTICALLY ACCEPTABLE COMPOUND OR SALT, AND / OR A HYDRATE, AND / OR A COCRYSTAL, AND / OR A PHARMACOLOGICAL COMBINATION OF THE COMPOUND) THAT INHIBIT (FOR EXAMPLE, ANTAGONIZE) THE INTERFERON GENE STIMULATOR (STING). These chemical entities are useful, for example, in treating a condition, disease, or disorder in which increased (e.g., excessive) Sting activation (e.g., Sting signaling) contributes to the pathology and / or symptoms and / or progression of the condition, disease, or disorder (e.g., cancer) in a subject (e.g., a human being). This disclosure also presents compositions containing these entities, as well as methods for using and preparing them.