MINIMALLY INVASIVE DEVICE AND METHOD FOR TIGHTENING SLACK SKIN BY LINEAR TIGHTENING AND STIMULATION OF COLLAGEN PRODUCTION, WHEREIN ANESTHESIA, HEAT AND INDUCTION OF ADDITIONAL COLLAGEN OR ANTI-INFLAMMATORY FLUIDS CAN BE APPLIED WITH THE SAME APPARATUS AND IN THE SAME AREA

Description

A PREFERRED EMBODIMENT ACCORDING TO THE PRINCIPLES OF THE PRESENT INVENTION PROVIDES A MINIMALLY INVASIVE DEVICE AND METHOD TARGETED AT COSMETIC PROCEDURES TO IMPROVE SKIN LAXITY AND DELAY THE SIGNS OF AGING IN HUMANS. In particular, the invention provides an innovative, low-cost, efficient, short-duration, painless, minimally invasive device and method for tightening a target tissue, preferably sagging skin, by means of linear tightening and stimulation of collagen production. The device not only allows heat to be applied directly to the dermis layer of the skin, but also allows an anesthetic and optionally additional treatment fluids to be delivered through the same device and into the same area. This overcomes many of the limitations of existing devices and procedures.(22) 01 / 20 / 2021 (30) 62 / 964,932 US, 01 / 23 / 2020; (51) P=A61K 38 / 00; S=A61K 38 / 26; S=A61P 3 / 04; S=A61P 3 / 10; S=C07K 14 / 575; S=C07K 14 / 605; (73) ELI LILLY AND COMPANY Address: Indianapolis, Indiana Country: UNITED STATES OF AMERICA (72) WATSON, BRIAN MORGAN; QU, HONGCHANG; LAI, XIANYIN; GEISER, ANDREA RENEE; ELSAYED, MOHAMMED ELSAYED HAMED; CUMMINS, ROBERT CHADWICK; BROWN, ROBERT ANDREW; ALSINA-FERNANDEZ, JORGE (74) FLAVIA AMOROSO DE SENA (54) GIP / GLP1 COAGONIST COMPOUNDS (57) The present invention relates to compounds that have activity at both the receptors for human glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). The present invention also relates to compounds that have a prolonged duration of action at each of these receptors. Furthermore, the present invention relates to compounds that can be administered orally. THE COMPOUNDS MAY BE USEFUL IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS (T2DM).The compounds may be useful in the treatment of obesity. A61K38 / 00; A61K38 / 26; A61P3 / 04; A61P3 / 10; C07K14 / 575; C07K14 / 605.