HETEROCYCLIC COMPOUND AS AN INHIBITOR OF CASEIN KINASE 1 AND / OR ACTIVIN RECEPTOR-TYPE KINASE 5

Description

An object of the present invention is to provide a compound having CK1 and / or ALK5 and similar inhibitory activity. THE OBJECT THEREOF CAN BE ACHIEVED BY A COMPOUND REPRESENTED BY THE FOLLOWING FORMULA (1): (1) WHEREIN R1 TO R10 EACH INDEPENDENTLY REPRESENTS HYDROGEN, ALKYL, CYCLOALKYL, OR A HALOGEN, WHEREIN R2 AND R3 OR R4 AND R5 TOGETHER WITH TWO CARBON ATOMS TO WHICH THEY ARE ATTACHED FORM A 5-MEMBERED RING CONTAINING A HETEROATOM SELECTED FROM THE GROUP CONSISTING OF AN OXYGEN ATOM, A NITROGEN ATOM, AND A SULFUR ATOM, OPTIONALLY SUBSTITUTED WITH ALKYL; OR ONE OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS, WHEREIN THE COMPOUND EXCLUDES 2-[4-(2,3-DIHYDRO-5-BENZUFRANYL)-2-(1,1-DIMETHYLETHYL)-1H-IMIDAZOLE-5-YL]-6-METHYLPYRIDINE.