Stable liquid pharmaceutical preparations containing antibodies
VN10060408BActive Publication Date: 2026-08-17REGENERON PHARMACEUTICALS INC
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Patent Information
- Application Number
- VN1202204808
- Authority / Receiving Office
- VN · VN
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2021-01-22
- Publication Date
- 2026-08-17
- Estimated Expiration
- 2041-01-22
Abstract
The invention proposes a stable pharmaceutical preparation containing a human antibody that specifically binds to the Eboia virus (EBOV). According to several design schemes, this preparation contains, in addition to the anti-EBOV antibody, a buffer, an amino acid, a non-ionic surfactant, and a stabilizer. The pharmaceutical preparations according to the invention demonstrate considerable stability of the antibody when stressed, e.g., agitated during transport and storage, e.g., stored at temperatures greater than 40°C.
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