METHOD FOR PRODUCING ANTIBODIES THAT SPECIFICALLY BIND TO COMPLEMENT 5 (C5) COMPONENT

Abstract

The invention relates to a monoclonal antibody that binds to complement factor 5 (C5) protein, and a method for using such antibody. According to various options of the invention, these antibodies are fully human antibodies that bind to the C5 protein. According to some options, the antibodies in the invention are useful for inhibiting or neutralizing C5 activity, thus providing a treatment or prevention for C5-related diseases or disorders in humans. According to some options, the invention relates to an anti-C5 antibody that has improved pharmacokinetic and pharmacodynamic properties, for example, a half-life of more than 10 days.