METHOD FOR EXTRACTING ARYLTETRALIN LIGNAN GLYCOSIDE FROM AGANONERION POLYMORPHUM PIERRE EX SPIRE (AGANONERION POLYMORPHUM PIERRE EX SPIRE)

Abstract

This paper proposes a method for extracting aryltetralin lignan glycoside compounds from the leaves of Agarwood (Agarwood morphum PieiTe ex Spire) belonging to the Apocynaceae family, in which the aryltetralin lignan glycoside compound was selected from a group including the compound (+)-α-β-β-D-glucopyranoside with formula (I), (-)-β-α-β-D-glucopyranoside with formula (I), (-)-β-α-β-D-glucopyranoside with formula (I), (-)-β-α-methoxyisosolar α-β-D-glucopyranoside with formula (III): The steps of this extraction method are described in detail in the description. The compounds in the invention all inhibit NO production in RAW 264.7 cells activated by lipopolysaccharide (lipopolysaccharide - LPS). The invention lays the groundwork for the proper use and guides further in-depth research on the *Lá giang* plant, a valuable food and medicinal plant of Vietnam that needs investment in research to become an important source of raw materials in the preparation and development of pharmaceuticals with preventive and therapeutic effects on inflammatory diseases.