Disinfectant

Abstract

The invention relates to a novel disinfectant composition comprising: A) from 0.1 to less than 10% by weight of propionic acid, relative to the total weight of the disinfectant composition; B) at least one straight-chain or branched-chain, fatty or cyclic diol of 4 to 8 carbon atoms; C) at least one surfactant selected from anionic, non-ionic, amphoteric, glycolipid surfactants and mixtures thereof; and D) water, the aforementioned disinfectant composition having a pH greater than 2.0 and less than the pKa of propionic acid, which is 4.87. This composition is particularly useful for disinfecting the udders and teats of animals, before or after milking, as well as for disinfecting surfaces such as open surfaces.

Description

Title of the invention: Disinfectant composition and its uses. Technical Field

[0001] The present invention relates to a novel disinfectant composition or biocidal composition comprising propionic acid and at least one diol, particularly useful for disinfecting the udders and teats of an animal, before or after milking, as well as for disinfecting surfaces such as open surfaces. The present invention relates in particular to a disinfectant composition compatible with European Regulation (EU) No. 528 / 2012, also called the "biocidal regulation", governing the rules relating to the making available on the market of biocidal products. According to Article 25 of this regulation, a biocidal product is eligible for the Simplified Marketing Authorization (SMAA) procedure if the following conditions are met: - the active substances present in the biocidal product are chosen from those authorized in European Regulation (EU) No. 528 / 2012 (Annex I) and comply with all the specified restrictions, - the biocidal product does not contain substances of concern to humans and the environment, - the biocidal product does not contain nanomaterials, - the biocidal product is sufficiently effective, and - handling and use of the biocidal product does not require personal protective equipment. Prior art

[0002] Patent EP 3 677 867 B1 describes biocidal products of plant origin comprising at least one organic acid, a chelating agent, a mixture of nonionic and anionic surfactants, and a natural fragrance. All these compositions are based on lactic acid. In their concentrated form, these products are irritating to the skin and can cause serious eye damage.

[0003] Patent FR 3 019 714 B1 describes a concentrated biodegradable biocide formulation based on lactic acid and / or citric acid, in combination with at least one sodium and / or potassium carboxylate. Such a formulation is classified as an irritant according to current regulations.

[0004] In March 2022, the classification of lactic acid changed. This raw material is now labeled H314 - H318 (H314: Causes skin burns and eye damage, H318: Causes serious eye damage). The presence of lactic acid in biocidal products today poses labelling problems.

[0005] Indeed, obtaining a Simplified Marketing Authorization (AMMS) for a biocidal product requires meeting the following objectives (i) to (iv): (i) No risk phrases H314 (causes skin burns and eye damage), H315 (causes skin irritation), H317 (may cause skin irritation), H318 (causes serious eye damage), H319 (causes serious eye irritation) shall appear on the label of the biocidal product: therefore, the active substances in Annex I covered by this classification shall be used at concentrations which do not result in product labelling. The handling and use of the biocidal product shall not require personal protective equipment. (ii) The choice of the active substance(s) must be made from among the active substances listed in categories 1 to 7 of Annex I to European Regulation (EU) No. 528 / 2012: Category 1: Substances permitted as food additives under Regulation (EC) No 1333 / 2008 with restrictions (the concentration must be limited to avoid classification as biocidal products under Directive 1999 / 45 / EC or Regulation No 1272 / 2008), Category 2: substances listed in Annex IV to Regulation (EC) No 1907 / 2006, Category 3: weak acids, Category 4: substances of natural origin traditionally used, Category 5: pheromones, Category 6: substances listed in Annex I or IA of European Regulation (EU) No. 528 / 2012, Category 7: other substances. (iii) Additional components present in the biocidal product must be used at concentrations which do not result in classification according to the criteria of European Regulation No. 1272 / 2008. (iv) The disinfectant efficacy of the biocidal product must be equivalent to that of conventional biocidal products, according to the efficacy tests indicated in the Biocidal Regulation and the Practical Guide to the Biocidal Products Regulation - ECHA, Volume II Efficacy - Evaluation and Assessment (Parts B + C). In addition, the biocidal product must meet an additional objective (v) which is that its properties (cleaning, foaming, cosmetic, rheological, depending on the intended application) must be equivalent or superior to those of existing biocidal products.

[0006] The solutions proposed to meet objectives (i) to (v) listed above are often antagonistic, so that it is difficult for a biocidal product to simultaneously meet all of these requirements. For example, the use of active substances that are aggressive towards microorganisms or in high concentrations to achieve the required disinfectant efficacy (objective (iv)) is not favorable to objective (i).

[0007] It has been discovered, and this constitutes the basis of the present invention, that it is possible to simultaneously meet the objectives (i) to (v) listed above by using specific components, and in particular by combining propionic acid and a diol with a linear or branched aliphatic or cycloaliphatic chain, having from 4 to 8 carbon atoms, which will be defined below. By choosing these specific constituents, the disinfectant composition of the invention has a high efficacy at the microbiological level (bactericidal and yeasticidal activity), while containing neither substances of concern for humans and the environment, nor nanomaterials (unlabeled composition). Thus, the disinfectant composition of the invention can be handled without personal protective equipment.

[0008] Thus, the disinfectant composition of the invention meets the requirements of udder hygiene of an animal before and after milking subjected to AMMS. It can also be used for open surface applications. Statement of the invention

[0009] Thus, a first object of the invention relates to a disinfectant composition comprising: A) from 0.1 to less than 10% by weight of propionic acid, relative to the total weight of the disinfectant composition, B) at least one diol with a linear or branched aliphatic or cycloaliphatic chain, having from 4 to 8 carbon atoms, and preferably having from 5 to 8 carbon atoms, C) at least one surfactant chosen from anionic, non-ionic, amphoteric, glycolipid surfactants, and mixtures thereof, and D) water, said disinfectant composition having a pH greater than 2.0 and less than 4.87.

[0010] A second subject of the invention relates to the use of a composition as described above for the disinfection of the udders and teats of an animal, before or after milking. The use of a composition as described above, for the disinfection of surfaces, is also part of the invention.

[0011] Another subject of the invention relates to a method for disinfecting the udders and teats of an animal before or after milking, comprising at least one step of applying a composition according to the invention to the udders and teats of the animal, before and / or after milking the animal.

[0012] Finally, a last object relates to a method for disinfecting a surface, comprising a step of applying a composition according to the invention to the surface to be disinfected. Detailed description

[0013] Thus, the first object of the invention relates to a disinfectant composition comprising: A) from 0.1 to less than 10% by weight of propionic acid of formula CH3CH2COOH, relative to the total weight of the disinfectant composition, B) at least one diol with a linear or branched aliphatic or cycloaliphatic chain, having from 4 to 8 carbon atoms, and preferably having from 5 to 8 carbon atoms, C) at least one surfactant chosen from anionic, non-ionic, amphoteric, glycolipid surfactants, and mixtures thereof, and D) water, said disinfectant composition having a pH greater than 2.0 and less than 4.87, the limit of 4.87 corresponding to the pKa value of propionic acid.

[0014] The propionic acid A) present in the composition can advantageously represent from 0.1 to 5%, and more preferably from 1 to 5%, by weight relative to the total weight of the disinfectant composition.

[0015] The diol B) present in the composition is advantageously chosen from 1,2-hexanediol, 2-methyl-1,3-propanediol, 2,3-butanediol (in particular meso-2,3-butanediol), isopentyldiol, 1,6-hexanediol, 1,2-pentanediol, 1,4-cyclohexanedimethanol, and mixtures thereof, preferably from 1,2-hexanediol, 1,6-hexanediol, 2,3-butanediol, and mixtures thereof, and more preferably 1,2-hexanediol, 1,6-hexanediol, and mixtures thereof.

[0016] In another particular embodiment, the diol B) is a vicinal diol with an aliphatic or cycloaliphatic chain, linear or branched, having from 4 to 6 carbon atoms, preferably 1,2-hexanediol, 2,3-butanediol, and their mixture, and more preferably 1,2-hexanediol.

[0017] The diol B) advantageously represents from 0.1 to less than 10%, and preferably from 1 to 8%, by weight relative to the total weight of the disinfectant composition.

[0018] Advantageously, the disinfectant composition of the invention is free of primary alcohol.

[0019] The disinfectant composition of the invention also comprises at least one surfactant chosen from anionic, non-ionic, amphoteric, glycolipid surfactants, and mixtures thereof. Surfactant C) is advantageously chosen from anionic, non-ionic surfactants, and mixtures thereof.

[0020] When the surfactant C) is an anionic surfactant, it is advantageously chosen from alkyl sulfonate salts, olefin sulfonate salts, paraffin sulfonate salts, glucoside sulfonate salts, alkyl sulfate salts, alkyl ether sulfate salts, alkyl taurate salts, acyl glutamate salts, alkyl ether carboxylic acids and salts thereof, and mixtures thereof, and preferably sodium lauryl glucoside hydroxypropyl sulfonate, sodium decyl glucoside hydroxypropyl sulfonate, sodium 2-ethylhexyl sulfate, sodium n-octyl sulfate, sodium lauryl sulfate, sodium laureth sulfate, sodium methyl cocoyl taurate, sodium lauroyl glutamate, sodium cocoyl glutamate, sodium capryloyl glutamate, capryleth-9 carboxylic acid, optionally in admixture with buteth-2 carboxylic acid, laureth-11 carboxylic acid, and mixtures thereof.The most preferred anionic surfactants are sodium n-octyl sulfate, sodium 2-ethylhexyl sulfate, sodium lauryl glucoside hydroxypropyl sulfonate, sodium lauroyl glutamate, sodium cocoyl glutamate, sodium capryloyl glutamate, and mixtures thereof.

[0021] When the surfactant C) is a non-ionic surfactant, it is advantageously chosen from sorbitan esters, glycerol esters, polyglycerol esters, alkyl polyglucosides, alkyl polypentosides, alkanoyl lactyl lactate, ethoxylated alcohols, ethoxylated castor oils, and mixtures thereof, and preferably sorbitan monolaurate, sorbitan monooleate, sorbitan sesquioctanoate, glyceryl caprylate / caprate, polyglyceryl-3 caprylate, polyglyceryl-4 caprate, C10-C16 alkyl polyglucosides, C5 and C10-C12 amyl xylosides, lauryl lactyl lactate, C10 alcohol ethoxylates (preferably with 6 EO), ethoxylated castor oils, and mixtures thereof. The most preferred nonionic surfactants are sorbitan monooleate, polyglyceryl-4 caprate, C10-C16 alkyl polyglucosides, ethoxylated castor oils (preferably with 33 EO), and mixtures thereof.

[0022] For the purposes of the invention, the term "alkyl" refers to a saturated, linear or branched aliphatic hydrocarbon group, preferably C1-C20, and more preferably C1-C12. The term "branched" means that at least one lower alkyl group such as methyl or ethyl is carried by a linear alkyl chain.

[0023] When surfactant C) is an amphoteric surfactant, it is advantageously chosen from sodium lauramphoacetate, sodium 2-ethyl hexyl iminodipropionate, and their mixture.

[0024] The surfactant C) advantageously represents from 0.1 to less than 10%, and preferably from 0.1 to 5%, by weight relative to the total weight of the disinfectant composition.

[0025] The disinfectant composition also comprises water D), which preferably represents from 40 to 99.5%, and more preferably from 75 to 95%, by weight relative to the total weight of the disinfectant composition.

[0026] In addition to the ingredients A) to D) previously described, the disinfectant composition according to the present invention may also comprise at least one moisturizing agent E). Said moisturizing agent E) is preferably chosen from polyols other than diol B), hyaluronic acid and its derivatives, alginates, urea, and mixtures thereof, and more preferably from polyols other than diol B) such as those chosen from glycerin, propylene glycol, sorbitol, xylitol, erythritol, mannitol, xylose, and mixtures thereof. Glycerin, propylene glycol, and mixtures thereof, are the most preferred moisturizing agents E).

[0027] The moisturizing agent E) advantageously represents from 0 to 30%, and preferably from 1 to 20%, by weight relative to the total weight of the disinfectant composition.

[0028] The disinfectant composition of the invention may also comprise at least one pH regulating agent F) the nature and quantity of which are chosen such that said composition has a pH greater than 2.0 and less than the pKa of propionic acid which is 4.87. The pH regulating agent of the invention may be: - either an acid such as hydrochloric acid and sulfuric acid, and preferably hydrochloric acid, - either a base such as sodium hydroxide and potassium hydroxide, and preferably sodium hydroxide.

[0029] The pH of the disinfectant composition of the invention is greater than 2.0 and less than the pKa of propionic acid which is 4.87. A pH less than 2.0 would automatically classify the disinfectant composition as H318 (causes serious eye damage). In a preferred embodiment of the invention, the pH of the disinfectant composition is greater than 2.1 and less than 4.0, and more preferably greater than 2.3 and less than 3.5.

[0030] The pH regulating agent F) advantageously represents from 0 to 1%, preferably from 0.01 to 0.5%, and more preferably from 0.01 to 0.25%, by weight relative to the total weight of the disinfectant composition.

[0031] The disinfectant composition of the invention may also comprise one or more excipients chosen from: - colorants, and preferably food colorants such as E104 (quinoline yellow), E10 (orange yellow S), E131 (patent blue V), E133 (brilliant blue FCP), and mixtures thereof, - opacifying agents, and preferably copolymers of acrylic-styrene and styrene-polyvinylpyrrolidone (PVP) type, - thickening agents, and preferably natural gums such as cellulose, xanthan, acacia, guar, diutan gums, and mixtures thereof.

[0032] The disinfectant composition of the invention is furthermore advantageously free of nanomaterials.

[0033] The disinfectant composition of the invention is in ready-to-use form.

[0034] The disinfectant composition of the invention is advantageously in liquid, gel or foam form. It can thus be applied by soaking or spraying.

[0035] Another object of the invention relates to the use of a disinfectant composition according to the invention, for the disinfection of the udders and teats of an animal, before and / or after milking.

[0036] Another use of the disinfectant composition of the invention is for the disinfection of surfaces, and preferably the disinfection of open surfaces.

[0037] Disinfection methods are also part of the invention.

[0038] According to one embodiment, the invention relates to a method for disinfecting the udders and teats of an animal before and / or after milking, said method comprising the steps of: (i) application of a disinfectant composition according to the invention to the udders and teats of the animal, before and / or after milking the animal, then (ii) optionally, removing said disinfectant composition from the udders and teats of the animal, preferably by wiping.

[0039] In step (i), the application of the disinfectant composition can be carried out either manually or automatically. In the latter case, the application can be carried out using a milking robot or an automated system.

[0040] When application step (i) is carried out before milking the animal, the contact time of the disinfectant composition on the udders and teats of the animal preferably varies from 30 seconds to 3 minutes, and more preferably from 30 seconds to 1 minute and 30 seconds.

[0041] When application step (i) is carried out after milking the animal, the contact time of the disinfectant composition on the udders and teats of the animal preferably is at least 5 minutes, and more preferably at least 30 seconds.

[0042] In step (ii), the removal of the disinfectant composition can be carried out by manual wiping (using paper or an individual cloth) or by any other automated system (milking robot).

[0043] When the method of disinfecting the udders and teats of an animal of the invention is carried out before milking, the disinfectant composition is removed according to option (ii).

[0044] When the method of disinfecting the udders and teats of an animal of the invention is carried out after milking, the disinfectant composition is not eliminated according to option (ii).

[0045] According to another embodiment, the invention relates to a method for disinfecting a surface comprising a step of applying a disinfectant composition according to the invention to a surface to be disinfected, and preferably to an open surface. The application step can be carried out either manually or automatically. The disinfectant composition can be applied by spraying, or in the form of foam. In addition, the application step can be followed by a rinsing and / or drying step.

[0046] In addition to the preceding provisions, the invention also comprises other provisions which will emerge from the additional description which follows, which relates to the preparation of disinfectant compositions of the prior art and according to the invention.

[0047] Examples:

[0048] The disinfectant compositions illustrated in the examples were prepared at room temperature, and the components were added under magnetic or electric stirring at 300 rpm in the order indicated in the formulations detailed below. All percentages indicated are percentages by weight.

[0049] The properties of the disinfectant compositions were then evaluated according to the efficacy tests described below, set out in the biocide regulation and the guide Practice of the Biocidal Products Regulation - ECHA, Volume II Efficacy - Evaluation and Assessment (Parts B + C): Phase 2, é suspension tests EN 1656 Standard (September 2019) Quantitative suspension test for the evaluation of the bactericidal activity of chemical antiseptics and disinfectants used in the veterinary field. The test method consists of dilution-neutralization. This method allows the biocidal action of the product to be stopped, thanks to the neutralizer, at the end of the tested contact time. The neutralizer used consists of Saponin 3.0%, Polysorbate 80 3.0%, Lecithin 0.3%, Sodium Thiosulfate 0.5%, L-Histidine 0.1% (percentages expressed in m / V), supplemented with distilled water. It is sterilized at 121°C for 15 min. The strains tested are Staphylococcus aureus (DMS 799), Escherichia Coii (DMS 682), Streptococcus uberis (DMS 20569). The formulations are diluted to 1% (non-effective concentration), 50% and 80% in distilled water (percentages expressed in V / V). The tests are carried out at 30 ± 1°C. The contact time is 1 min ± 5 seconds for pre-milking products and 5 min ± 10 seconds for post-milking products. The tests are carried out in the presence of an interfering substance: 3 g / L of bovine albumin for the products before milking, which corresponds to low-level dirt conditions (sterilization by filtration on a membrane with a porosity of 0.45 pm) and 10 g / L of skimmed milk powder for the products after milking (sterilization at 121°C for 5 min). Once neutralized, the tested dilutions are deposited on tryptone-soy agar (TSA). The incubation of the strains is carried out at 37 ± 1°C over two cycles of between 20 and 24 hours. The counting technique is a depth count (colony count). The product tested must exhibit a reduction of at least 5 log decimals under the test conditions. Standard EN 1657 (May 2016) Quantitative suspension test for the evaluation of the fungicidal or yeasticidal activity of chemical antiseptics and disinfectants used in the veterinary field. The test method consists of dilution-neutralization. This method allows the biocidal action of the product to be stopped, thanks to the neutralizer, at the end of the tested contact time. The neutralizer used consists of Saponin 3.0%, Polysorbate 80 3.0%, Lecithin 0.3%, Sodium Thiosulfate 0.5%, L-Histidine 0.1% (percentages expressed in m / V), supplemented with distilled water. It is sterilized at 121°C for 15 min. The strain tested is Candida albicans (DMS 1386). The 125% concentrated formulations are diluted to 0.8% (non-effective concentration), 64% and 80% in distilled water (percentages expressed in V / V). The tests are carried out at 30 ± 1°C. The contact time is 1 min ± 5 seconds for the pre-milking products and 5 min ± 10 seconds for the post-milking products. The tests are carried out in the presence of an interfering substance: 3 g / L of bovine albumin for the products before milking, which corresponds to low-level dirt conditions (sterilization by filtration on a membrane with a porosity of 0.45 pm) and 10 g / L of skimmed milk powder for the products after milking (sterilization at 121°C for 5 min). Once neutralized, the tested dilutions are deposited on malt extract agar (MEA). The strains are incubated at 30 ± 1°C for two cycles of between 20 and 24 hours. The counting technique is a depth count (colony count). The product tested must exhibit a reduction of at least 4 log decimals under the test conditions. Phase 2, e 2: Surface tests of standard EN 17422 (June 2020) Quantitative surface test for the evaluation of teat disinfectants used in the veterinary field - Specific test for bactericidal activity The test method consists of dilution-neutralization. This method allows the biocidal action of the product to be stopped, thanks to the neutralizer, at the end of the tested contact time. The neutralizer used consists of Saponin 3.0%, Polysorbate 80 3.0%, Lecithin 0.3%, Sodium Thiosulfate 0.5%, L-Histidine 0.1% (percentages expressed in m / V), supplemented with distilled water. It is sterilized at 121°C for 15 min. The strains tested are Staphylococcus aureus (DMS 799) and Escherichia Coii (DM S 682). The formulations are tested pure (100%) and diluted to 1% (non-effective concentration) and 80% in distilled water (percentages expressed in V / V). The tests are carried out at 30 ± 1°C. The contact time is 1 min ± 5 seconds for pre-milking products and 5 min ± 10 seconds for post-milking products. The tests are carried out in the presence of an interfering substance: 3 g / L of bovine albumin for the products before milking, which corresponds to low-level dirt conditions (sterilization by filtration on a membrane with a porosity of 0.45 pm) and 10 g / L of skimmed milk powder for the products after milking (sterilization at 121°C for 5 min). The test surfaces are 4 cm Vitro Skin synthetic skins 2(2 cm x 2 cm). They are cut aseptically and then placed at room temperature in a rehydration chamber containing 300 mL of a 15% glycerin solution, for a period of between 16 and 24 hours maximum. 50 pL of a mixture [strain + interfering substance] are placed on the skin, which is then placed in an incubator at 30 ± 1°C for 15 min. Then, the skin is immersed in 10 mL of test solution for 30 seconds, then drained, and placed in an incubator at 30 ± 1°C (test temperature) for the defined contact time reduced by 30 seconds. It is then transferred into the neutralizer, then deposited on tryptone-soy agar (TSA). The incubation of the strains is carried out at 37 ± 1°C over two cycles of between 20 and 24 hours. The counting technique is a depth count (colony count). The product subjected to a test carried out under pre-milking conditions must present a reduction at least equal to 3 decimal logs. The product subjected to a test carried out under post-milking conditions must present a reduction at least equal to 4 decimal logs. Standard EN 13697 + Al (July 2019): Quantitative non-porous surface test for the evaluation of the bactericidal and / or fungicidal activity of chemical disinfectants used in the food industry, industry, domestic and community areas. The test method is without mechanical action and prescriptions (phase 2, step 2). The test method consists of dilution-neutralization. This method allows the biocidal action of the product to be stopped, thanks to the neutralizer, at the end of the tested contact time. The neutralizer used consists of Saponin 3.0%, Polysorbate 80 3.0%, Lecithin 0.3%, Sodium Thiosulfate 0.5%, L-Histidine 0.1% (percentages expressed in m / V), supplemented with distilled water. It is sterilized at 121°C for 15 min. The strain tested is Candida albicans (DMS 1386). The incubation temperature of the strain is 30 ± 1°C for a period of 48 hours. The tests are carried out at 20 ± 1°C. The contact times are 5 min ± 10 seconds and 10 min ± 10 seconds. The tests are carried out in the presence of an interfering substance: 0.3 g / L of bovine albumin, which corresponds to clean conditions (sterilization by filtration on a membrane with a porosity of 0.45 pm). The test surfaces are 304 stainless steel discs (2 cm in diameter) with both sides having a grade 2b finish (cleaned in a 5% DECON solution for 60 minutes, rinsed in distilled water for 10 seconds then sterilized in a bath containing 70% (V) isopropanol for 15 minutes then dried under a laminar air flow). 50 pL of a mixture [strain + interfering substance] are placed on the disc which is then placed in an incubator at 37 ± 1°C until visible drying which should not exceed 1 hour. 100 μl of the product under test are applied so as to cover the dried film. The surface is maintained at 20°C for the defined contact times. The surface is transferred into the neutralization medium so as to immediately neutralize the disinfectant. The number of surviving organisms that can be recovered from the surface is determined quantitatively. The detachment of microorganisms from the disc is achieved by contact and friction of the surface with 3 mm diameter glass beads. The number of yeasts present on a surface treated with hard water instead of treated with the disinfectant is also determined and the reduction in the number of viable cells attributed to the product is calculated by difference. In the case of bactericidality, the submitted product must show a reduction of at least 4 log decimals under the test conditions. In the case of yeast control, the submitted product must show a reduction of at least 3 log decimals under the test conditions. [00501 Example 1: Disinfectant composition for udder hygiene according to the invention intended for post-milking Composition of Example 1 (% by weight): 2% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 6% 1,2-hexanediol 8% glycerin 1% castor oil 33 EO 0.001% of a “ready-to-use” coloring mixture comprising 90% E102 (tartrazine yellow) and 10% E131 (patent blue V) 0.008% of a colorant E102 (tartrazine yellow) 0.08% NaOH at 50% to adjust pH to 3.5 QSP water Classification of the composition of exemole 1: Specific concentration limits of propionic acid: If [active ingredient] = 100%: H314 (causes skin burns and eye damage) - H318 (causes serious eye damage) - H335 (may cause respiratory irritation) - H226 (highly flammable liquid and vapor). If 25% < [ma] < 100%: H314 (causes skin burns and eye damage) - H318 (causes serious eye damage) Specific concentration limit for the calculation of H314 and H318 = 25. If 10% < [ma] < 25% => H315 (causes skin irritation) - H319 (causes serious eye irritation) Specific concentration limit for the calculation of H315 and H319 = 10. If [ma] > 10% => H335 (may cause respiratory irritation). Specific concentration limits of washing soda: If [ma] = 100%: H314 (causes skin burns and eye damage) - H290 (may be corrosive to metals). If 2% < [ma] < 100%: H314 (causes skin burns and eye damage) and H318 (causes serious eye damage) Specific concentration limit for the calculation of H314 and H318 = 2 If 0.5% < [ma] < 2%: H315 (causes skin irritation) and H319 (causes serious eye irritation) Specific concentration limit for the calculation of H315 and H319 = 0.5. Eye calculation: H318: Only propionic acid and sodium hydroxide solution should be considered. 2 / 25 + 0.04 / 2 = 0.1 < 1 the mixture is not classified H318. H319: Only propionic acid, sodium hydroxide, and 1,2-hexanediol should be considered 2 / 10 + 0.04 / 0.5 + 6 / 10 = 0.88 < 1 the mixture is not classified H319 Skin calculus: H314: Only propionic acid and sodium hydroxide solution should be taken into account. account 2 / 25 + 0.04 / 2 = 0.1 < 1 the mixture is not classified H314 H315: Only propionic acid and sodium hydroxide solution should be considered. 2 / 10 + 0.04 / 0.5 = 0.28 < 1 the mixture is not classified H315 The product is not classified. Disinfectant efficacy: Phase 2, step 1: EN 1656: 5 min, 30°C, 10 g / L skimmed milk on the limiting germ Staphylococcus aureus: 80% effective EN 1657: 5 min, 30°C, 10 g / L skimmed milk on Candida albicans: 100% effective Phase 2, step 2: EN 17422: 5 min, 30°C, 10 g / L skimmed milk on the limiting germ Staphylococcus aureus: 100% effective These results show that the composition of Example 1 is effective, that it does not contain any substances of concern for humans and the environment, nor any nanomaterials. The composition is therefore eligible for AMMS. The composition of Example 1 was then tested for udder hygiene: the composition was sprayed using a conventional manual sprayer (supplier: CNTT) of IL onto the teats of an animal. No unpleasant odor was detected during milking. 51~l Example 2: Disinfectant composition for udder hygiene according to the invention intended for post-milking Composition of Example 2 (% by weight): 2% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 4% 1,2-hexanediol 8% glycerin 1% sodium n-octyl sulfate 0.001% of a “ready-to-use” coloring mixture comprising 90% E102 (tartrazine yellow) and 10% E131 (patent blue V) 0.008% of a colorant E102 (tartrazine yellow) 0.02% HCl at 33% to adjust pH to 2.8 QSP water Classification of the composition of Example 2: Specific concentration limits of propionic acid: See example 1 Specific concentration limits of sodium n-octyl sulfate: If [ma] > 20%: H318 (causes serious eye damage) Specific concentration limit for the calculation of H318 = 20. If 10% < [ma] < 20%: H319 (causes serious eye irritation) Specific concentration limit for the calculation of H319 = 10. Specific concentration limits of hydrochloric acid: If [ma] = 100%: H314 (causes skin burns and eye damage), H318 (causes serious eye damage), H335 (may cause respiratory irritation), H290 (may be corrosive to metals). If 25% < [ma] < 100%: H314 (causes skin burns and eye damage), H318 (causes serious eye damage), H335 (may cause respiratory irritation) Specific concentration limit for the calculation of H314 and H318 = 25. If 10% < [ma] < 25%: H315 (causes skin irritation), H319 (causes serious eye irritation), H335 (may cause respiratory irritation) Specific concentration limit for the calculation of H315 and H319 = 10. Eye calculation: H318: Only propionic acid, sodium n-octyl sulfate and hydrochloric acid should be considered 2 / 25 + 1 / 20 + 0.007 / 25 = 0.13 < 1 the mixture is not classified H318 H319: Only propionic acid, sodium n-octyl sulfate, hydrochloric acid, and 1,2-hexanediol should be considered 2 / 10 + 1 / 10 + 0.007 / 10 + 4 / 10 = 0.7 < 1 the mixture is not classified H319 Skin calculus: H314: Only propionic acid and hydrochloric acid should be considered 2 / 25 + 0.007 / 25 = 0.08 < 1 the mixture is not classified H314 H315: Only propionic acid, sodium n-octyl sulfate and hydrochloric acid should be considered 2 / 10 + 1 / 10 + 0.007 / 10 = 0.3 < 1 the mixture is not classified H315 The product is not classified. Disinfectant efficacy: Phase 2, step 1: EN 1656: 5 min, 30°C, 10 g / L skimmed milk on Staphylococcus aureus, E. Coll, Streptococcus uberis: 50% effective EN 1657: 5 min, 30°C, 10 g / L skimmed milk on Candida albicans: 100% effective Phase 2, step 2: EN 17422: 5 min, 30°C, 10 g / L skimmed milk on Staphylococcus aureus, E. Coll: 100% effective These results show that the composition of Example 2 is effective, that it does not contain any substances of concern for humans and the environment, nor any nanomaterials. The composition is therefore eligible for AMMS. The composition of Example 2 was then tested for udder hygiene: the composition was sprayed using a conventional manual sprayer (supplier: CNTT) of IL onto the teats of an animal. No unpleasant odor was detected during milking. A slight foam formed upon application, which helps the product stay on the teats and allows good visibility of the applied product. Good distribution of the product on the teats was observed. 521 Example 3: Disinfectant composition for udder hygiene according to the invention intended for before milking Composition of Example 3 (% by weight): 2% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 6% 1,2-hexanediol 8% glycerin 5% xylitol 1% sodium n-octyl sulfate 0.8% sodium lauryl glucoside hydroxypropyl sulfonate 0.009% of a colorant E104 (quinoline yellow) 0.0001% of a colorant E133 (brilliant blue) 0.12% HCl at 33% to adjust pH to 2.3 QSP water Classification of the composition of Example 3: Specific concentration limits of propionic acid: See example 1 Specific concentration limits of sodium n-octyl sulfate and hydrochloric acid: See example 2 Eye calculation: H318: Only propionic acid, sodium n-octyl sulfate and hydrochloric acid should be considered. 2 / 25 + 1 / 20 + 0.04 / 25 = 0.14 < 1 the mixture is not classified H318 H319: Only propionic acid, sodium n-octyl sulfate, hydrochloric acid and 1,2-hexanediol should be considered 2 / 10 + 1 / 10 + 0.04 / 10 + 6 / 10 = 0.9 < 1 the mixture is not classified H319 Skin calculus: H314: Only propionic acid and hydrochloric acid should be considered 2 / 25 + 0.04 / 25 = 0.08 < 1 the mixture is not classified H314 H315: Only propionic acid, hydrochloric acid, and sodium n-octyl sulfate should be considered 2 / 10 + 0.04 / 10 + 1 / 10 = 0.3 < 1 the mixture is not classified H315 The product is not classified. Disinfectant efficacy: Phase 2, step 1: EN 1656: 1 min, 30°C, 3 g / L of bovine albumin on the limiting germ Staphylococcus aureus: 80% effective EN 1657: 1 min, 30°C, 3 g / L of bovine albumin on Candida albicans: 100% effective Phase 2, step 2: EN 17422: 1 min, 30°C, 3 g / L of bovine albumin on the limiting germ Staphylococcus aureus: 100% efficiency These results show that the composition of Example 3 is effective, that it does not contain any substances of concern for humans and the environment, nor any nanomaterials. The composition is therefore eligible for AMMS. The composition of Example 3 was then tested for udder hygiene: the composition was sprayed using a conventional manual sprayer (supplier: CNTT) of IL onto the teats of an animal. No unpleasant odor was detected during milking. A slight foam formed upon application, which helps the product stay on the teats and allows good visibility of the applied product. Good distribution of the product on the teats was observed, and also good cleaning. f 00531 Example 4: Disinfectant composition for udder hygiene according to the invention intended for post-milking Composition of Example 4 (% by weight): 1% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 7% 1,2-hexanediol 1% sodium 2-ethylhexyl iminodipropionate 0.77% 33% HCl to adjust pH to 2.3 QSP water Classification of the composition of Example 4: Specific concentration limits of propionic acid: See example 1 Specific concentration limits of hydrochloric acid: See example 2 Eye calculation: H318: Only propionic acid and hydrochloric acid should be considered. 1 / 25 + 0.25 / 25 = 0.05 < 1 the mixture is not classified H318 H319: Only propionic acid, hydrochloric acid and 1,2-hexanediol should be considered 1 / 10 + 0.25 / 10 +7 / 10 = 0.83 < 1 the mixture is not classified H319 Skin calculus: H314: Only propionic acid and hydrochloric acid should be considered 1 / 25 + 0.25 / 25 = 0.05 < 1 the mixture is not classified H314 H315: Only propionic acid and hydrochloric acid should be considered 1 / 10 + 0.25 / 10 = 0.13 < 1 the mixture is not classified H315 The product is not classified. Disinfectant efficacy: Phase 2, step 1: EN 1656: 5 min, 30°C, 10 g / L skimmed milk on the limiting germ Staphylococcus aureus: 80% effective EN 1657: 5 min, 30°C, 10 g / L skimmed milk on Candida albicans: 100% effective Phase 2, step 2: EN 17422: 5 min, 30°C, 10 g / L skimmed milk on the limiting germ Staphylococcus aureus: 100% effective These results show that the composition of Example 4 is effective, that it does not contain any substances of concern for humans and the environment, nor any nanomaterials. The composition is therefore eligible for AMMS. 541 Example 5: Disinfectant composition for breast hygiene according to the invention Composition of Example 5 (% by weight): 2% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 6% 1,2-hexanediol 8% glycerin 5% xylitol 1% sodium n-octyl sulfate 0.8% sodium lauryl glucosides hydroxypropyl sulfonate 0.12% HCl at 33% to adjust pH to 2.3 QSP water Disinfectant efficacy: Phase 2, step 1: EN 1657: 1 min, 30°C, 3 g / L of bovine albumin on Candida albicans: 100% effective (reduction > 4.39 log for 4 log required). 551 Comparative example 1: Disinfectant composition compared to example 1 based on lactic acid A comparative composition to the composition of Example 1 was prepared, in which propionic acid was replaced by lactic acid Composition of Comparative Example 1 (% by weight): 2% lactic acid 6% 1,2-hexanediol 8% glycerin 1% castor oil 33 EO 0.001% of a “ready-to-use” coloring mixture comprising 90% E102 (tartrazine yellow) and 10% E131 (patent blue V) 0.008% of a colorant E102 (tartrazine yellow) 0.28% sodium hydroxide solution to adjust pH to 3.5 QSP water Classification of the composition of comparative example 1: Eye calculation: H318: only lactic acid and sodium hydroxide solution need to be considered 2 / 3 + 0.28 / 2 = 0.81 < 1 the mixture is not classified as H318. H319: only lactic acid, sodium hydroxide solution, and 1,2-hexanediol need to be considered 2 / 1 + 0.28 / 0.5 + 6 / 10 = 3.16 > 1 the mixture is classified as H319 Skin calculus: H314: only lactic acid and sodium hydroxide solution need to be taken into account 2 / 5 + 0.28 / 2 = 0.54 < 1 the mixture is not classified as H314 H315: only lactic acid and sodium hydroxide solution need to be taken into account 2 / 1 + 0.28 / 0.5 = 2.56 > 1 the mixture is classified as H315 The product is therefore classified, and does not comply with the objective (iii) previously set out (absence of classification according to the criteria of European regulation no. 1272 / 2008).

[0056] Comparative example 2: Disinfectant composition compared to example 2 based on lactic acid A comparative composition to the composition of Example 2 was prepared, in which propionic acid was replaced by lactic acid Composition of Comparative Example 2 (% by weight): 2% lactic acid 4% 1,2-hexanediol 8% glycerin 1% sodium n-octyl sulfate 0.001% of a “ready-to-use” coloring mixture comprising 90% E102 (tartrazine yellow) and 10% E131 (patent blue V) 0.008% of a colorant E102 (tartrazine yellow) 0.08% sodium hydroxide solution to adjust pH to 2.8 QSP water Classification of the composition of comparative example 2: Eye calculation: H318: Only lactic acid, sodium n-octyl sulfate and sodium hydroxide solution should be considered 2 / 3 + 1 / 20 + 0.08 / 2 = 0.76 < 1 the mixture is not classified H318 H319: Only lactic acid, sodium n-octyl sulfate, sodium hydroxide solution and 1,2-hexanediol should be considered 2 / 1 + 1 / 10 + 0.08 / 0.5 + 4 / 10 = 2.66 > 1 the mixture is classified H319 Skin calculus: H314: only lactic acid and sodium hydroxide solution need to be considered 2 / 5 + 0.08 / 2 = 0.44 < 1 the mixture is not classified H314 H315: only lactic acid, sodium n-octyl sulfate and sodium hydroxide solution need to be considered 2 / 1 + 1 / 10 + 0.08 / 0.5 = 2.26 > 1 the mixture is classified H315 The product is therefore classified, and does not comply with the objective (iii) previously set out (absence of classification according to the criteria of European regulation no. 1272 / 2008). [00571 Comparative Example 3: Disinfectant composition compared to Example 3 based on lactic acid A comparative composition to the composition of Example 3 was prepared, in which propionic acid was replaced by lactic acid Composition of Comparative Example 3 (% by weight): 2% lactic acid 6% 1,2-hexanediol 8% glycerin 5% xylitol 1% sodium n-octyl sulfate 0.8% sodium lauryl glucoside hydroxypropyl sulfonate 0.009% of a colorant E104 (quinoline yellow) 0.0001% of a colorant E133 (brilliant blue) 0.04% HCl at 33% to adjust pH to 2.3 QSP water Classification of the composition of comparative example 3: Eye calculation: H318: Only lactic acid, sodium n-octyl sulfate and hydrochloric acid should be considered 2 / 3 + 1 / 20 + 0.013 / 25 = 0.72 < 1 the mixture is not classified H318 H319: Only lactic acid, sodium n-octyl sulfate, hydrochloric acid and 1,2-hexanediol should be taken into account 2 / 1 + 1 / 10 + 0.013 / 10 + 6 / 10 = 2.7 > 1 the mixture is classified H319 Skin calculus: H314: only lactic acid and hydrochloric acid need to be considered 2 / 5 + 0.013 / 25 = 0.40 < 1 the mixture is not classified H314 H315: only lactic acid, hydrochloric acid, and sodium n-octyl sulfate need to be considered 2 / 1 + 0.013 / 10 + 1 / 10 = 2.1 > 1 the mixture is classified H315 The product is therefore classified and does not comply with the objective (iii) previously referred to (absence of classification according to the criteria of European regulation n°1272 / 2008). :if 4 Disinfectant composition compared to example 4 based on lactic acid Composition of comparative example 4 (% by weight): 1% lactic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 7% 1,2-hexanediol 1% sodium 2-ethylhexyl iminodipropionate 0.68% HCl at 33% to adjust pH to 2.3 QSP water Classification of the composition of Example 4: Eye calculation: H318: Only lactic acid and hydrochloric acid should be considered. 1 / 3 + 0.22 / 25 = 0.34 < 1 the mixture is not classified H318 H319: only lactic acid, hydrochloric acid and 1,2-hexanediol must be taken into account 1 / 1 + 0.22 / 10 +7 / 10 = 1.72 > 1 the mixture is classified H319 Skin calculus: H314: Only lactic acid and hydrochloric acid should be considered 1 / 5 + 0.22 / 25 = 0.21 < 1 the mixture is not classified H314 H315: only lactic acid and hydrochloric acid must be taken into account 1 / 1 + 0.22 / 10 = 1.022 > 1 the mixture is classified H315 The product is therefore classified and does not comply with the objective (iii) previously referred to (absence of classification according to the criteria of European regulation n°1272 / 2008). Disinfectant composition compared to Example 5 Composition of comparative example 5 (% by weight): 2% propionic acid (active substance listed in Annex I of European Regulation (EU) No. 528 / 2012) 0% 1,2-hexanediol 8% glycerin 5% xylitol 1% sodium n-octyl sulfate 0.8% sodium lauryl glucosides hydroxypropyl sulfonate 0.11% HCl at 33% to adjust pH to 2.3 QSP water Disinfectant efficacy: Phase 2, step 1: EN 1657: 1 min, 30°C, 3 g / L of bovine albumin on Candida albicans: not effective (reduction < 3.02 log for 4 log required). The product does not meet the objective (iv) set out above; it does not achieve the disinfectant efficacy set out in the Biocidal Regulation and the Practical Guide to the Biocidal Products Regulation - ECHA, Volume II Efficacy - Evaluation and Assessment (Parts B + C). Following the same protocol as the previous examples, two compositions based on propionic acid and 1,2-hexanediol were compared to two similar compositions in which 1,2-hexanediol was replaced by citric acid. The formulations and results are summarized in Table 1 below (the % indicated are % by weight): [Table 1] Compositions comprising a mixture of propionic acid and 1,2-hexanediol showed efficacy within 1 minute. Compositions free of 1,2-hexanediol showed no efficacy even after 5 minutes. [00581 Example 7: Disinfectant compositions according to the invention for use before milking Following the same protocol as the previous examples, three compositions based on propionic acid and 1,2-hexanediol were prepared and tested before treatment. The formulations and results are summarized in Table 2 below (the % indicated are % by weight): [Table 2] The three compositions 7a, 7b and 7c showed efficacy before treatment in 30 seconds. (00591 Example 8: Disinfectant composition according to the invention for surface disinfection Composition of Example 8 (% by weight): 2% propionic acid 0.5% 1,2-hexanediol 1% sodium n-octyl sulfate 0.08% 33% HCl to adjust pH to 2.3 QSP water Classification of the composition of Example 8: Specific concentration limits of propionic acid: See Example 1 Specific concentration limits of sodium n-octyl sulfate and hydrochloric acid: See example 2 Eye calculation: H318: Only propionic acid, sodium n-octyl sulfate and sodium hydrochloric acid must be taken into account 2 / 25 + 1 / 20 + 0.003 / 25 = 0.13 < 1 — ► the mixture is not classified H318 H319: Propionic acid, sodium n-octyl sulfate, hydrochloric acid and 1,2-hexanediol should be taken into account 2 / 10 + 1 / 10 + 0.08 / 10 + 0.5 / 10 = 0.36 < 1 — ► the mixture is not classified H319 Skin calculus: H314: Only propionic acid and hydrochloric acid should be considered 2 / 25 + 0.08 / 25 = 0.08 < 1 — ► the mixture is not classified H314 H315: Only propionic acid, sodium n-octyl sulfate and hydrochloric acid should be considered 2 / 10 + 1 / 10 + 0.08 / 10 = 0.31 < 1 — ► the mixture is not classified H315 The product is not classified. Disinfectant efficacy: Phase 2, step 2: EN 13697 (most limiting test): 10 min, 20°C, 0.3 g / L of bovine albumin on Candida albicans: 100% effective These results show that the composition of Example 5 is effective, that it does not contain any substances of concern for humans and the environment, nor any nanomaterials. The composition is therefore eligible for AMMS. [00601 Example 9: Evaluation of different diols Different diols were evaluated in the following basic formula 1 (% indicated are % by weight): [Table 3] The results obtained are summarized in Table 4 below: [Table 4] Two other diols were compared on the following base formula 2 (% indicated are % by weight): [Table 5] The results obtained are summarized in Table 6 below: [Table 6]

Claims

Claims 1. Disinfectant composition characterized in that it comprises: A) from 0.1 to less than 10% by weight of propionic acid, relative to the total weight of the disinfectant composition, B) at least one diol with a linear or branched aliphatic or cycloaliphatic chain, having from 4 to 8 carbon atoms, and preferably having from 5 to 8 carbon atoms, C) at least one surfactant chosen from anionic, non-ionic, amphoteric, glycolipid surfactants, and mixtures thereof, and D) water, said disinfectant composition having a pH greater than 2.0 and less than 4.

87.

2. Disinfectant composition according to claim 1, characterized in that the propionic acid A) represents from 0.1 to 5%, and preferably from 1 to 5%, by weight relative to the total weight of the disinfectant composition.

3. Disinfectant composition according to claim 1 or claim 2, characterized in that the diol B) is chosen from 1,2-hexanediol, 2-methyl-1,3-propanediol, 2,3-butanediol, isopentyldiol, 1,6-hexanediol, 1,2-pentanediol, 1,4-cyclohexanedimethanol, and mixtures thereof, preferably 1,2-hexanediol, 1,6-hexanediol, 2,3-butanediol, and mixtures thereof, and more preferably 1,2-hexanediol, 1,6-hexanediol, and mixtures thereof.

4. Disinfectant composition according to one of claims 1 to 3, characterized in that the diol B) is a vicinal diol with an aliphatic or cycloaliphatic chain, linear or branched, having from 4 to 6 carbon atoms, preferably 1,2-hexanediol, 2,3-butanediol, and their mixture, and more preferably 1,2-hexanediol.

5. Disinfectant composition according to one of claims 1 to 4, characterized in that the diol B) represents from 0.1 to less than 10%, and preferably from 1 to 8%, by weight relative to the total weight of the disinfectant composition.

6. Disinfectant composition according to one of claims 1 to 5, characterized in that the surfactant C) is chosen from anionic and non-ionic surfactants, and their mixtures.

7. Disinfectant composition according to claim 6, characterized in that the surfactant C) is an anionic surfactant chosen from alkyl sulfonate salts, olefin sulfonate salts, paraffin sulfonate salts, glucoside sulfonate salts, alkyl sulfate salts, alkyl ether sulfate salts, alkyl taurate salts, acyl glutamate salts, alkyl ether carboxylic acids and their salts, and mixtures thereof, preferably chosen from sodium lauryl glucoside hydroxypropyl sulfonate, sodium decyl glucoside hydroxypropyl sulfonate, sodium 2-ethylhexyl sulfate, sodium n-octyl sulfate, sodium lauryl sulfate, sodium laureth sulfate, sodium methyl cocoyl taurate, sodium lauroyl glutamate, sodium cocoyl glutamate, sodium capryloyl glutamate, capryleth-9 carboxylic acid, optionally in mixture with buteth-2 carboxylic acid, laureth-11 carboxylic acid,and mixtures thereof, and more preferably sodium n-octylsulfate, sodium lauryl glucoside hydroxypropyl sulfonate, sodium 2-ethylhexyl sulfate, sodium lauroyl glutamate, sodium cocoyl glutamate, sodium capryloyl glutamate, and mixtures thereof., 8. Disinfectant composition according to claim 6, characterized in that the surfactant C) is a non-ionic surfactant chosen from sorbitan esters, glycerol esters, polyglycerol esters, alkyl polyglucosides, alkyl polypentosides, alkanoyl lactyl lactate, ethoxylated alcohols, ethoxylated castor oils, and mixtures thereof, preferably sorbitan monolaurate, sorbitan monooleate, sorbitan sesquioctanoate, glyceryl caprylate / caprate, polyglyceryl-3 caprylate, polyglyceryl-4 caprate, C10-C16 alkyl polyglucosides, C5 and C10-C12 amyl xylosides, lauryl lactyl lactate, C10 ethoxylated alcohols, castor oils ethoxylated, and mixtures thereof, and more preferably sorbitan monooleate, polyglyceryl-4 caprate, C10-C16 alkyl polyglucosides, ethoxylated castor oils, and mixtures thereof.

9. Disinfectant composition according to one of claims 1 to 8, characterized in that the surfactant C) represents from 0.1 to less than 10%, and preferably from 0.1 to 5%, by weight relative to the total weight of the disinfectant composition.

10. Disinfectant composition according to one of claims 1 to 9, characterized in that said composition further comprises at least one moisturizing agent E), preferably chosen from polyols other than diol B), hyaluronic acid and its derivatives, alginates, urea, and mixtures thereof, more preferably from polyols other than diol B) such as those chosen from glycerin, propylene glycol, sorbitol, xylitol, erythritol, mannitol, xylose, and mixtures thereof, and even more preferably glycerin, propylene glycol, and mixtures thereof.

11. Disinfectant composition according to claim 10, characterized in that the moisturizing agent E) represents from 0 to 30%, and preferably from 1 to 20%, by weight relative to the total weight of the disinfectant composition.

12. Disinfectant composition according to one of claims 1 to 11, characterized in that said composition further comprises at least one pH regulating agent F) the nature and quantity of which are chosen such that said composition has a pH greater than 2.0 and less than 4.87, said pH regulating agent being chosen from acids such as hydrochloric acid and sulfuric acid, or bases such as sodium hydroxide and potassium hydroxide.

13. Disinfectant composition according to claim 12, characterized in that the pH regulating agent F) represents from 0 to 1%, preferably from 0.01 to 0.5%, and more preferably from 0.01 to 0.25%, by weight relative to the total weight of the disinfectant composition.

14. Disinfectant composition according to one of claims 1 to 13, characterized in that the pH of said composition is greater than 2.1 and less than 4.0, and preferably greater than 2.3 and less than 3.

5.

15. Disinfectant composition according to one of claims 1 to 14, characterized in that said composition further comprises one or more excipients chosen from colorants, opacifying agents, thickening agents.

16. Disinfectant composition according to one of claims 1 to 15, characterized in that said composition is in liquid, gel or foam form, and can be applied by dipping or spraying.

17. Use of a composition according to one of claims 1 to 16, for the disinfection of the udders and teats of an animal, before or after milking.

18. Use of a composition according to one of claims 1 to 16, for the disinfection of surfaces, and preferably for the disinfection of open surfaces.

19. Method for disinfecting the udders and teats of an animal before or after milking, comprising the steps of: (i) application of a composition according to one of claims 1 to 16 to the udders and teats of the animal, before and / or after milking the animal, then (ii) optionally, removing said composition from the udders and teats of the animal, preferably by wiping.

20. A method according to claim 19 for disinfecting the udders and teats of an animal, wherein the contact time of the disinfectant composition on the udders and teats of the animal during step (i), before milking the animal, varies from 30 seconds to 3 minutes, and preferably from 30 seconds to 1 minute and 30 seconds.

21. A method according to claim 19 for disinfecting the udders and teats of an animal, wherein the contact time of the disinfectant composition on the udders and teats of the animal during step (i), after milking the animal, is at least 5 minutes, and preferably at least 30 seconds.

22. Method for disinfecting a surface, characterized in that it comprises a step of applying a composition according to one of claims 1 to 16 to the surface to be disinfected, and preferably to an open surface, said application step being optionally followed by a rinsing and / or drying step.