COMPOUNDS THAT REGULATE THE ACTIVITY OF MICROARN-124

Abstract

The compound disclosed in the invention is intended to regulate the activity of microRNA-124. The compound has the structure as shown by formula (I), and the compound can be used to prevent or treat inflammatory diseases including, but not limited to, inflammatory bowel disease, rheumatoid arthritis, Crohn's disease, ulcerative colitis, multiple sclerosis, Alzheimer's disease, Parkinson's disease, osteoarthritis, atherosclerosis, ankylosing spondylitis, psoriasis, dermatitis, Sjogren's syndrome, bronchitis, asthma, and inflammation associated with colon cancer, and specifically, inflammatory bowel disease, rheumatoid arthritis, Crohn's disease, ulcerative colitis, multiple sclerosis, osteoarthritis, ankylosing spondylitis, psoriasis, Sjogren's syndrome, bronchitis, and inflammation associated with colon cancer.