Dietary fibre formulations
A 3:1 ratio of High Amylose Maize Starch to psyllium in a dietary fibre formulation protects against premature fermentation, promoting butyrate production in the distal colon and improving gut health for IBS patients without exacerbating symptoms, addressing the challenge of finding low-FODMAP fibre sources.
WO2025007187A1PCT designated stage expired Publication Date: 2025-01-09EDITH COWAN UNIV
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Patent Information
- Application Number
- PCT/AU2024/050721
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-07-03
- Filing Date
- 2024-07-02
- Publication Date
- 2025-01-09
Abstract
A method of treating a person suffering from Irritable Bowel Syndrome (IBS) and other gut-related conditions which involves providing a source of fibre while not aggravating the IBS symptoms in the person, where the method comprises: administering to the person a dietary fibre formulation comprising a ratio of approximately 3 parts high amylose maize starch (HAMS) to 1 part psyllium; wherein the person is administered increasing volumes of the formulation for at least two weeks in an initial ramp-up period; wherein the psyllium protects against fermentation of the HAMS as the formulation passes through the proximal colon, and wherein the HAMS can be fermented in the distal colon of the person to produce butyrate and faeces; and wherein the symptoms of IBS in the person are not substantially aggravated by administration of the formulation.
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