Instantly-visible biological detection kit

Abstract

An instantly-visible biological detection kit, comprising a base (10) and an injection assembly (20). The base (10) is provided with an accommodation cavity for placement of a test tube prefilled with a detection reagent, and a first test tube insertion hole (11a) leading to the accommodation cavity. The injection assembly (20) comprises an injection barrel (21) and a reaction base (22), the reaction base (22) connecting the base (10) and the injection barrel (21) and being located between the base (10) and the injection barrel (21). The injection barrel (21) is provided with a liquid injection channel (21A) for placement of a test tube prefilled with a diluent reagent and a detection channel (21B) for placement of a detection test paper sample. The reaction base (22) is provided with a mixing cavity (22A) communicated with the liquid injection channel (21A), the detection channel (21B) and the first test tube insertion hole (11a), the liquid injection channel (21A) being located above the mixing cavity (22A), and the mixing cavity (22A) being located above the first test tube insertion hole (11a).

Description

Instant Visual Bioassay Kit

[0001] This application claims priority to the Chinese patent application filed with the China Patent Office on September 5, 2023, with application number 202311140065.1 and invention name “Instant Visualization Biological Detection Kit”, the entire contents of which are incorporated by reference into the application. Technical Field

[0002] The present application relates to the field of medical detection technology, and in particular to an instant visual biological detection kit. Background Art

[0003] Microbial testing is generally done by adding the sample to be tested into a test tube pre-filled with detection reagents for a mixing reaction. After the reaction is completed, the mixed liquid is dropped onto a test paper, and the type of microorganism is determined based on the color change of the test paper.

[0004] For some expensive detection reagents such as incubation reagents, it is not possible to add a large dose to the reaction tube and then perform the subsequent test paper test. It is necessary to add a diluent that does not affect the test results to the test tube to dilute the detection reagent and heat it before conducting microbial detection.

[0005] In related detection technologies, a test tube pre-filled with detection reagents is typically placed in the base of a test kit. A diluent is then added through the upper opening of the test tube to increase the reagent volume, allowing it to contact the test paper and trigger a color reaction. The inventors discovered that achieving the sample-in, result-out detection effect for microorganisms in this solution often requires complex structures and automated designs. This not only increases the cost of the test kit but also limits its wide range of applications. Furthermore, the limited space within the test tube prevents it from accommodating larger quantities of detection reagents and amplification fluid. This results in very limited space available for mixing the two liquids, resulting in poor fluidity and uneven mixing when the two liquids are mixed. This results in inaccurate test results when the mixture of the two liquids is used for microbial testing. Technical issues

[0006] The main purpose of this application is to provide an instant visual biological detection kit, which aims to increase application scenarios and improve detection accuracy while reducing production costs by optimizing the structural design. Technical Solutions

[0007] To achieve the above objectives, the instant visual biological detection kit proposed in this application includes a base and an injection component:

[0008] A base, the base being provided with a cavity for placing a test tube pre-filled with a detection reagent, and a test tube hole communicating with the cavity;

[0009] An injection assembly, comprising a syringe and a reaction seat, wherein the reaction seat connects the base and the syringe and is located between the base and the syringe; the syringe is provided with an injection channel for inserting a test tube pre-filled with a dilution reagent and a detection channel for inserting a test paper sample; the reaction seat is provided with a mixing chamber connecting the injection channel, the detection channel and the first test tube insertion hole; the injection channel is located above the mixing chamber, and the mixing chamber is located above the first test tube insertion hole.

[0010] In one embodiment of the present application, the reaction seat is provided with a collision mixing portion, and a second test tube insertion hole is provided on the bottom wall of the reaction seat; the collision mixing portion is arranged around the inner side wall of the reaction seat near the second test tube insertion hole, and the collision mixing portion and the inner bottom wall of the reaction seat enclose a mixing collision chamber;

[0011] The mixing chamber comprises a mixing collision chamber and a second test tube insertion hole.

[0012] In one embodiment of the present application, the reaction seat is provided with a horizontal outer folding edge, and the horizontal outer folding edge is integrally formed on the outer side wall of the reaction seat close to the injection barrel, and the injection barrel abuts against the horizontal outer folding edge.

[0013] In one embodiment of the present application, an injection reinforcement portion is provided on a side of the injection barrel facing the reaction seat, the injection reinforcement portion protruding from at least a portion of the injection barrel, and the injection reinforcement portion abuts against the collision mixing portion;

[0014] The injection channel and the detection channel pass through the injection reinforcement part.

[0015] In one embodiment of the present application, the detection channel is located above the mixing collision chamber.

[0016] In one embodiment of the present application, the detection channel and the injection channel extend in the same direction.

[0017] In one embodiment of the present application, the injection assembly further comprises a side pressure member, and the injection barrel is provided with a first limiting groove for movement of the side pressure member;

[0018] The first limiting groove is connected to the injection channel and the outside world;

[0019] The side pressure member abuts against the groove wall of the first limiting groove.

[0020] In one embodiment of the present application, at least a portion of the side of the side pressure member facing the injection barrel is provided with an open groove, and the open groove passes through the side pressure member from top to bottom.

[0021] In one embodiment of the present application, the side pressure member is provided with a second limiting groove, and the injection cylinder further includes a limiting rod; the limiting rod is provided on the groove wall of the first limiting groove on the side facing away from the reaction seat, and the second limiting groove accommodates the limiting rod.

[0022] In one embodiment of the present application, the base includes a protrusion, the protrusion is provided with a reaction limiting cavity and a first test tube insertion hole, and the protrusion is integrally formed with the base;

[0023] The reaction limiting cavity is connected to the first test tube jack and the outside world;

[0024] The reaction seat is located in the reaction limiting cavity, and one end of the horizontal outer fold facing away from the injection cylinder abuts against the protrusion. Beneficial effects

[0025] In the technical solution of the present application, the instant visual biological detection kit includes a base and an injection component, the injection component includes a syringe and a reaction seat, the reaction seat has a mixing chamber of a certain size, when the injection channel of the syringe is placed in a test tube with an opening at one end and an integrally formed test tube bladder and a wax-sealed dilution reagent test tube at the other end, the bladder is squeezed to increase the air pressure in the test tube, forcing the dilution reagent to break through the wax seal structure and be injected into the mixing chamber of the reaction seat below; at the same time, the mixing chamber is connected to the detection channel, injection channel and test tube below. On the basis of optimizing the structure of the detection box, the applicant injects the dilution reagent downward, and the dilution reagent will immediately generate a force on the detection reagent. Under the action of this force, the detection reagent will be squeezed out of the test tube, and the two liquids will mix with each other, and as With the addition of the diluent, the two reagents will collide in the mixing chamber and further fully mix. At the same time, due to the limitation of the reaction seat, the mixed liquid of the two reagents will not be lost when it contacts the detection reagent for sample detection. Except for a part of the mixed liquid absorbed by the test paper, the rest of the mixed liquid is always in the mixing chamber for mixing, and the detection reagent will also be mixed with the diluent when it is squeezed out of the test tube by the diluent. In addition, the mixing chamber increases the mixing space of the two reagents and improves the fluidity of the liquid. In addition, the diluent refluxes from top to bottom and then from bottom to top, making its flow path longer. The diluent needs to fill the detection reagent test tube and the mixing chamber above, with a longer flow path and mixing time, further improving the mixing effect of the two reagents. In summary, the instant visual biological detection kit simplifies the detection process and increases the use scenarios of the instant visual biological detection kit on the basis of reducing costs, and can also make the detection reagent and the diluent reagent evenly mixed and fully through the reaction seat, effectively improving the detection accuracy and avoiding inaccurate test results. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0027] FIG1 is a schematic diagram of the three-dimensional structure of an embodiment of the instant visual biological detection kit provided by the present application;

[0028] FIG2 is a cross-sectional view along line AA in FIG1 ;

[0029] FIG3 is a schematic diagram of the three-dimensional structure of an embodiment of a syringe provided in the present application;

[0030] FIG4 is a schematic diagram of the three-dimensional structure of an embodiment of a reaction seat provided in the present application;

[0031] FIG5 is a schematic diagram of the three-dimensional structure of an embodiment of a base provided in the present application;

[0032] FIG6 is a schematic diagram of the three-dimensional structure of an embodiment of a side pressure member provided by the present application;

[0033] FIG7 is a schematic diagram of the three-dimensional structure of an embodiment of the injection kit provided by the present application;

[0034] FIG8 is a schematic diagram of the three-dimensional structure of an embodiment of the first cover provided in the present application.

[0035] Description of Figure Numbers:

[0036] Reference numerals: Reference numerals: 10 base 213 limiting rod 11 protrusion 22 reaction seat 11a first test tube insertion hole 22A mixing chamber 11A reaction limiting chamber 22A1 mixing collision chamber 20 injection assembly 221 collision mixing part 21 injection cylinder 222 horizontal outer fold 21A injection channel 22a second test tube insertion hole 21B detection channel 23 side pressure member 211 injection reinforcement part 23A opening groove 212 transparent member 23B second limiting groove 21a visualization window 24 first cover 21C first limiting groove

[0037] The realization of the objectives, functional features and advantages of this application will be further explained in conjunction with embodiments and with reference to the accompanying drawings. Modes for Carrying Out the Invention

[0038] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0039] It should be noted that all directional indications in the embodiments of the present application (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0040] In addition, the descriptions of "first", "second", etc. in this application are for descriptive purposes only and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "and / or" appearing throughout the text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but this must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0041] The instant visual biological detection kit proposed in the present application is shown in Figures 1 to 8. The instant visual biological detection kit includes a base 10 and an injection assembly 20: the base 10 is provided with a cavity for inserting a test tube pre-filled with a detection reagent, and a test tube hole connected to the cavity; the injection assembly 20 includes a syringe 21 and a reaction seat 22, the reaction seat 22 connects the base 10 and the syringe 21 and is located between the base 10 and the syringe 21; the syringe 21 is provided with an injection channel 21A for inserting a test tube pre-filled with a dilution reagent and a detection channel 21B for inserting a test paper sample, and the reaction seat 22 is provided with a mixing chamber 22A connecting the injection channel 21A, the detection channel 21B and the first test tube insertion hole 11a, the injection channel 21A is located above the mixing chamber 22A, and the mixing chamber 22A is located above the first test tube insertion hole 11a.

[0042] In the technical solution of the present application, the instant visual biological detection kit includes a base 10 and an injection component 20. The injection component 20 includes a syringe 21 and a reaction seat 22. The reaction seat 22 has a mixing chamber 22A of a certain size. When the injection channel 21A of the syringe 21 is placed in a dilution reagent test tube with an opening at one end and an integrally formed test tube bag and a wax-sealed test tube at the other end, the bag is squeezed to increase the air pressure in the test tube and force the dilution reagent to break through the wax seal structure. The dilution reagent is injected into the mixing chamber 22A of the reaction seat 22 below; at the same time, the mixing chamber 22A is connected to the upper detection channel 21B, the injection channel 21A and the lower test tube pre-installed with the detection reagent. On the basis of optimizing the structure of the detection box, the applicant injects the dilution reagent downward, and the dilution reagent will immediately generate a force on the detection reagent. Under the action of this force, the detection reagent will be squeezed When the two liquids come out of the test tube, they mix with each other, and with the addition of the diluent, the two reagents will collide in the mixing chamber 22A and be further fully mixed. At the same time, there is a restriction on the reaction seat 22, and the mixed liquid of the two reagents will not be lost when it contacts the detection reagent for sample detection. Except for a part of the mixed liquid absorbed by the test paper, the rest of the mixed liquid is always in the mixing chamber 22A for mixing, and the detection reagent will also be mixed with the diluent when it is squeezed out of the test tube by the diluent. In addition, the mixing chamber 22A increases the mixing space of the two reagents and improves the fluidity of the liquid. In addition, the diluent refluxes from top to bottom and then from bottom to top, making its flow path longer. The diluent needs to fill the detection reagent test tube and the mixing chamber 22A above, with a longer flow path and mixing time, which further improves the mixing effect of the two reagents. In summary, the instant visual biological detection kit simplifies the detection process and increases the use scenarios of the instant visual biological detection kit on the basis of reducing costs, such as outpatient and emergency departments, communities, homes, etc., where rapid detection is required and the detection cost is not too high. In addition, the detection reagent and the dilution reagent can be evenly mixed through the reaction seat 22, effectively improving the detection accuracy and avoiding inaccurate test results.

[0043] The base 10 includes an upper cover and a bottom box. The upper cover is arranged on the bottom box to form an internal space of the base 10. The inventor has set a common heating component in the base 10, and the test tube pre-filled with the detection reagent is heated by the heating component. At the same time, a common prompt light is also provided to remind that the heating time is up. When the heating component starts heating, the prompt light is red. When the heating time set by the heating component is reached, the prompt light is green. Because this design is a common technical means, it will not be explained in detail here.

[0044] The reaction base 22 is cylindrical in shape, with a mixing chamber 22A disposed in the middle along its length. The mixing chamber 22A extends through the upper portion of the reaction base 22. A second test tube insertion hole 22a is provided on the bottom wall of the reaction base 22, giving the reaction base 22 an overall through-hole structure. The mixing chamber 22A primarily provides a space outside the base 10 for fully mixing the detection reagent and the dilution reagent, thereby reducing the overall volume of the base 10 and lowering production costs. The reaction base 22 is disposed on the exterior of the base 10 and can abut against the outer surface of the base 10. Alternatively, the base 10 may include a groove that matches the size of the bottom of the reaction base 22. Alternatively, a protrusion 11 that can accommodate the reaction base 22 can be provided on the upper cover of the base 10. The specific connection method is not limited, as long as the corresponding cavity structures are interconnected to ensure accurate liquid contact. The inventor arranges the mixing chamber 22A on the outside of the base 10 in order to reduce the overall volume of the base 10 and reduce production costs, because other related detection functional components such as the above-mentioned heating component and indicator light usually need to be placed inside the base 10. If the mixing chamber 22A is built-in, the overall volume of the base 10 will inevitably be increased, or the base 10 will protrude downward at the first test tube insertion hole 11a to make way for related structures. However, this design will cause the center of gravity of the instant visual biological detection kit to move upward, resulting in the risk of unstable placement and the hidden danger of many detection problems. At the same time, the reaction seat 22 can also provide a larger space for reagent mixing and enhance the fluidity of the liquid. Therefore, the inventor arranges the reaction seat 22 outside the base 10 to solve the above problems.

[0045] The syringe 21 is generally elongated and cylindrical in shape. Inside the syringe 21, there are provided an injection channel 21A that prevents the test tube from falling, and a detection channel 21B that stably holds the test strip. It is worth noting that the test tube containing the diluent reagent has openings at both ends, but one end is sealed with a bladder, while the other end is wax-sealed. By aligning the syringe 21 with the mixing chamber 22A of the reaction base 22 and squeezing the bladder, the gas within the bladder flows toward the test tube, forcing the diluent reagent to squeeze the other end of the test tube, thereby breaking through the wax and being injected into the mixing chamber 22A. Because the lower end of the mixing chamber 22A is connected to the test tube containing the detection reagent, the diluent reagent exerts an impact on the detection reagent, forcing it to be ejected. At the same time, because the groove wall of the mixing chamber 22A limits the size of the contact space, the continuously injected diluent reagent mixes with the detection reagent and continuously impacts the groove wall, resulting in a thorough mixing of the two reagents.

[0046] The inventors also created a visualization window 21a in the detection channel 21B, connecting the detection channel 21B to the outside world. A transparent member 212 then covers the visualization window 21a and is integrally molded with the syringe 21. The visualization window 21a is positioned to facilitate reading test results and can be adjusted to the position of the detection channel 21B. It is understood that the transparent member 212 can be made of either polypropylene or polyethylene, with no material restrictions, as long as it is transparent and does not affect the chemical properties of the detection mixture. Furthermore, considering the need to prevent airborne dust contamination of the instant visual biological test kit after the test, the inventors provided a first cover 24 and a second cover. The second cover includes a blocking portion and a cap, which is integrally formed with the blocking portion and is longer than the blocking portion. The first cover 24 covers the upper portion of the syringe 21, preventing dust from entering the detection channel 21B and the injection channel 21A. It is understood that the first and second covers 24 and 21 are primarily used for dust protection, and no size restrictions are imposed, as long as they meet the requirements of the intended use.

[0047] In one embodiment of the present application, as shown in FIG4 , the reaction seat 22 is provided with a collision mixing portion 221 , and a second test tube insertion hole 22 a is provided on the bottom wall of the reaction seat 22 . The collision mixing portion 221 is disposed around the inner side wall of the reaction seat 22 near the second test tube insertion hole 22 a , and the collision mixing portion 221 and the inner bottom wall of the reaction seat 22 enclose a mixing collision chamber 22A1 .

[0048] The mixing chamber 22A includes a mixing collision chamber 22A1 and a second test tube insertion hole 22a.

[0049] In this embodiment, the collision mixing portion 221 is an annular structure connected end to end, which is arranged on the inner wall of the reaction seat 22 near the second test tube insertion hole 22a. The collision mixing portion 221 and the bottom wall of the reaction seat 22 form a mixing collision chamber 22A1 with a smaller diameter. The mixing chamber 22A includes the mixing collision chamber 22A1 and the second test tube insertion hole 22a. When the diluted reagent injected from the top falls and collides and mixes with the detection reagent, they will overflow into the mixing collision chamber 22A1 together. As the dose in the cavity increases and the diluted reagent has a certain impact force, combined with the reduction of the mixing space, the mixed reagent will quickly collide with the collision mixing portion 221, accelerating and intensifying the mixing of the two, which can effectively improve the mixing degree of the two reagents.

[0050] In one embodiment of the present application, as shown in FIG. 4 , the reaction seat 22 is provided with a horizontal outer fold 222 , which is integrally formed on the outer side wall of the reaction seat 22 close to the injection cylinder 21 , and the injection cylinder 21 abuts against the horizontal outer fold 222 .

[0051] In this embodiment, the inventor provides a horizontal outer folded edge 222 at one end of the reaction seat 22 away from the second test tube insertion hole 22a. The injection molding process or the die-casting process can be selected according to the specific material of the reaction seat 22 so that the horizontal outer folded edge 222 is integrally formed on the outer peripheral wall of the reaction seat 22 to form a 90-degree angle. When the reaction seat 22 is placed on the base 10 and the first test tube insertion hole 11a and the second test tube insertion hole 22a are aligned, the end of the syringe 21 facing the reaction seat 22 abuts against the reaction seat 22. The user can apply a downward force to the reaction seat 22 to tightly connect the reaction seat 22 and the syringe 21 to prevent the mixed liquid from leaking. At the same time, the horizontal outer folded edge 222 increases the contact area with the syringe 21, which can improve the stability of the contact between the two.

[0052] In one embodiment of the present application, as shown in Figure 3, an injection reinforcement portion 211 is provided on the side of the syringe 21 facing the reaction seat 22, and the injection reinforcement portion 211 protrudes from at least a portion of the syringe 21, and the injection reinforcement portion 211 abuts the collision mixing portion 221; the injection channel 21A and the detection channel 21B pass through the injection reinforcement portion 211.

[0053] In this embodiment, at least the surface of the side of the syringe 21 facing the reaction seat 22 radiates from the center point to the surrounding areas and protrudes uniformly downward to form an injection reinforcement portion 211. The injection reinforcement portion 211 can be inserted into the mixing chamber 22A and abut against the injection reinforcement block. The detection channel 21B and the injection channel pass through the injection reinforcement portion 211, so that the distance between the detection reagent and the dilution reagent is shortened. In addition, the top of the mixing collision chamber 22A1 will be blocked by the bottom wall of the injection reinforcement portion 211, so that the mixed reagent can collide on all sides of the mixing collision chamber 22A1, accelerating and intensifying the mixing; at the same time, the injection reinforcement portion 211 of the syringe 21 is inserted into the mixing chamber 22A, which not only further improves the contact stability between the syringe 21 and the reaction seat 22, but also increases the abutment area between the reaction seat 22 and the syringe 21 to prevent the mixed liquid from leaking.

[0054] In one embodiment of the present application, as shown in FIG. 1 and FIG. 2 , the detection channel 21B is located above the mixing collision chamber 22A1 .

[0055] In this embodiment, the inventors arrange the detection channel 21B above the mixing collision chamber 22A1, so that the space of the mixing collision chamber 22A1 can be fully utilized to fully mix the detection reagent and the dilution reagent. In this way, the detection test strip can contact all the mixed reagents regardless of whether it is placed horizontally or vertically, and the mixed reagent will not flow out of the mixing collision chamber 22A1. The detection strip achieves the detection purpose by absorbing the mixed reagent.

[0056] In one embodiment of the present application, as shown in FIG2 , the detection channel 21B and the injection channel 21A extend in the same direction.

[0057] In this embodiment, the detection channel 21B is set in the same direction as the injection channel 21A, extending along the length of the syringe 21. After the dilution reagent is injected, the mixed reagent of the dilution reagent and the detection reagent will first contact the test paper to complete the detection. The advantage of the detection channel 21B and the injection channel 21A extending in the same direction is that the longitudinal space of the syringe 21 can be fully utilized, the lateral volume of the syringe 21 can be compressed, and the material and cost of producing the syringe 21 can be reduced. In addition, the detection channel 21B set in this direction can also prevent the mixed reagent from diffusing on the test paper, resulting in blurred or unclear test results; and the vertically placed test paper can more evenly wet the entire test area, which helps to ensure accurate test results and avoid misjudgment or missed detection due to uneven wetting of the liquid.

[0058] In one embodiment of the present application, as shown in Figures 3 and 6, the injection assembly 20 also includes a side pressure member 23, and the injection cylinder 21 is provided with a first limiting groove 21C for the movement of the side pressure member 23; the first limiting groove 21C connects the injection channel 21A and the outside world; the side pressure member 23 abuts the groove wall of the first limiting groove 21C.

[0059] In this embodiment, to facilitate squeezing of the pouch containing the test tube containing the diluted reagent, the inventors have provided a first retaining groove 21C on the side of the syringe barrel 21. This first retaining groove 21C connects the injection channel 21A with the outside world, allowing the pouch containing the test tube to be confined within the first retaining groove 21C. Furthermore, the inventors have provided a side pressure member 23 with arc-shaped sides, which ensures a more uniform squeezing effect. By pushing the side pressure member 23, it moves along the sidewalls of the first retaining groove 21C toward the pouch, thereby squeezing the pouch. Furthermore, using the side pressure member 23 for squeezing has an additional advantage over manual squeezing: the pressure member is confined within the first retaining groove 21C, providing a constant force on the pouch. As the amount of mixed reagent below increases, some reagent may flow back into the injection channel 21A, reducing detection accuracy. Manual squeezing, however, requires constant squeezing of the pouch, resulting in ineffective operation. Therefore, using the side pressure member 23 is more suitable.

[0060] In one embodiment of the present application, as shown in FIG6 , at least a portion of the side of the side pressure member 23 facing the injection cylinder 21 is provided with an open groove 23A, and the open groove 23A passes through the side pressure member 23 from top to bottom.

[0061] In this embodiment, an open groove 23A is provided on at least a portion of the side of the side pressure piece 23 facing the injection cylinder 21, and the open groove 23A passes through the side pressure piece 23 from top to bottom. By squeezing the side pressure piece 23 near the open groove 23A, the side pressure piece 23 can be quickly pushed into the first limiting groove 21C. In addition, the open groove 23A enables the two outer sides of the side pressure piece 23 to apply a force to open the groove wall of the first limiting groove 21C. Under the action of this force, the friction between the side pressure piece 23 and the groove wall of the first limiting groove 21C can be increased to prevent the liquid from flowing back and pushing open the side pressure piece 23.

[0062] In one embodiment of the present application, as shown in Figures 6 and 7, the side pressure member 23 is provided with a second limiting groove 23B, and the injection cylinder 21 also includes a limiting rod 213; the limiting rod 213 is arranged on the groove wall of the first limiting groove 21C on the side facing away from the reaction seat 22, and the second limiting groove 23B passes through the side pressure member 23; the second limiting groove 23B accommodates the limiting rod 213.

[0063] In this embodiment, based on the consideration that the side pressure piece 23 may move out of the first limit groove 21C when moving outward, the inventor provides a limit rod 213 in the first limit groove 21C, and the limit rod 213 is perpendicular to the bottom wall of the first limit groove 21C, that is, the groove wall of the first limit groove 21C on the side facing away from the reaction seat 22; the inventor opens a second limit groove 23B that runs through the middle part of the side pressure piece 23, and in order to accommodate the limit rod 213, the width of the second limit groove 23B is slightly larger than the width of the limit rod 213, and at the same time, in order to facilitate the squeezing of the opening groove 23A, the second limit groove 23B is also connected to the opening groove 23A. When one inspection is completed, the next inspection needs to be carried out, which requires moving the side pressure piece 23 that squeezes the bladder outward. After the side pressure piece 23 moves a certain distance, the groove wall of the second limiting groove 23B will abut the limiting rod 213, preventing the side pressure piece 23 from continuing to move outward. In this way, there is no need to worry about the side pressure piece 23 being pulled outward with too much force and moving the side pressure piece 23 out as a whole.

[0064] In one embodiment of the present application, as shown in Figures 1 to 8, the base 10 includes a protrusion 11, which is provided with a reaction limiting cavity 11A and a first test tube insertion hole 11a, and the protrusion 11 is integrally formed on the base 10; the reaction limiting cavity 11A connects the first test tube insertion hole 11a and the outside world; the reaction seat 22 is located in the reaction limiting cavity 11A, and the end of the horizontal outer folded edge 222 facing away from the injection barrel 21 abuts against the protrusion 11.

[0065] A protrusion 11 is provided on the surface of the base 10, i.e., the upper cover mentioned above. The protrusion 11 can be integrally formed on the upper cover by an injection molding process or a die-casting process of the specific material of the base 10. A reaction limiting cavity 11A is opened in the protrusion 11 and a first test tube insertion hole 11a is opened at the bottom. The reaction limiting cavity 11A is connected to the first test tube insertion hole 11a. The reaction seat 22 is placed in the reaction limiting cavity 11A, and one side of the lower surface of the horizontal outer side abuts the protrusion 11. In this way, when the syringe 21 is used for injection, no sliding will occur between the syringe 21, the reaction and the base 10. At the same time, after the biological sample is tested, because the horizontal outer side protrudes from the base 10, it is also convenient to take out and separate the various parts, and the operation is simple.

[0066] To better explain the present application, the application method of the instant visual biological detection kit in one embodiment of the present application is as follows:

[0067] 4 , first, insert the test tube pre-filled with the test reagent in the freeze-dried state through the second test tube jack 22a, and use the tube wall at the opening of the test tube to buckle on the inner bottom wall of the reaction seat 22 to prevent it from loosening;

[0068] 5 , the reaction base 22 a with the test tube fixed thereon is placed into the protrusion 11 of the base 10 , and the test tube passes through the first test tube insertion hole 11 a of the protrusion 11 and enters the interior of the base 10 ;

[0069] 1 and 2 , the test strip is first placed from the bottom of the syringe 21 into the detection channel 21B. Considering the problem of test reagents falling, the applicant has limited the inner diameter of the detection channel 21B through the production process when producing the instant visual biological detection kit to prevent the test strips from falling. Then, the dilution test tube pre-filled with the dilution reagent is placed into the injection channel 21A through the top of the syringe 21, with a portion of the lower opening of the dilution test tube extending out of the injection channel 21A. It is understandable that the order of the two operations involved in the third step is not fixed, and the dilution pipette can also be placed first and then the test strip.

[0070] 3 , 4 , 5 , and 1 , the syringe 21 provided with the test strip and the dilution test tube is inserted into the reaction seat 22 . From the above explanation of the various structures, it can be easily understood that after the syringe 21 is inserted into the reaction seat 22 , the injection reinforcement portion 211 contacts the collision mixing portion 221 , and a portion of the test strip and the dilution test tube extends into the mixing collision chamber 22A1 .

[0071] 6 and 7 , the side pressure member 23 moves along the groove wall of the first limiting groove 21C of the syringe 21 toward the groove wall of the first limiting groove 21C facing the side pressure member 23. The inward movement of the side pressure member 23 squeezes the bladder of the dilution reagent. As the squeezed volume increases, the air in the bladder flows toward the dilution test tube and squeezes the dilution reagent. The dilution reagent then breaks through the wax seal structure below the dilution test tube and is injected into the reaction seat 22, and the reagent mixing and detection process explained above is then carried out.

[0072] 6 and 7 , after the detection is completed, the side pressure piece 23 moves outward a certain distance, and the groove wall of the second limiting groove 23B will abut the limiting rod 213. Since the width of the opening groove 23A of the side pressure piece 23 is smaller than the width of the limiting rod 213, the limiting rod 213 can limit the distance that the side pressure piece 23 moves outward, thereby preventing the side pressure piece 23 from being pulled out by force.

[0073] The above description is merely an embodiment of the present application and does not limit the patent scope of the present application. All equivalent structural transformations made using the contents of the present application specification and drawings under the inventive concept of the present application, or direct / indirect application in other related technical fields are included in the patent protection scope of the present application.

Claims

1. An instant visual biological detection kit, wherein: The instant visual biological detection kit comprises: A base (10), the base (10) being provided with a cavity for inserting a test tube pre-filled with a detection reagent, and a first test tube insertion hole (11a) communicating with the cavity; and An injection assembly (20), the injection assembly (20) comprising a syringe (21) and a reaction seat (22), the reaction seat (22) connecting the base (10) and the syringe (21) and being located between the base (10) and the syringe (21); the syringe (21) being provided with an injection channel (21A) for inserting a test tube pre-filled with a dilution reagent and a detection channel (21B) for inserting a test paper sample; the reaction seat (22) being provided with a mixing chamber (22A) communicating with the injection channel (21A), the detection channel (21B) and the first test tube insertion hole (11a); the injection channel (21A) being located above the mixing chamber (22A), and the mixing chamber (22A) being located above the first test tube insertion hole (11a).

2. The instant visual biological detection kit according to claim 1, wherein: The reaction seat (22) is provided with a collision mixing portion (221), and the bottom wall of the reaction seat (22) is provided with a second test tube insertion hole (22a); The collision mixing portion (221) is arranged around the inner side wall of the reaction seat (22) close to the second test tube insertion hole (22a), and the collision mixing portion (221) and the inner bottom wall of the reaction seat (22) are enclosed to form a mixing collision chamber (22A1); The mixing chamber (22A) includes the mixing collision chamber (22A1) and the second test tube insertion hole (22a).

3. The instant visual biological detection kit according to claim 1, wherein: The reaction seat (22) is provided with a horizontal outer folded edge (222), and the horizontal outer folded edge (222) is integrally formed on the outer side wall of the reaction seat (22) close to the injection cylinder (21), and the injection cylinder (21) abuts against the horizontal outer folded edge (222).

4. The instant visual biological detection kit according to claim 2, wherein: An injection reinforcement portion (211) is provided on a side of the injection cylinder (21) facing the reaction seat (22), the injection reinforcement portion (211) protruding from at least a portion of the injection cylinder (21), and the injection reinforcement portion (211) abuts against the collision mixing portion (221); The injection channel (21A) and the detection channel (21B) penetrate the injection reinforcement portion (211).

5. The instant visual biological detection kit according to claim 2, wherein: The detection channel (21B) is located above the mixing collision chamber (22A1).

6. The instant visual biological detection kit according to claim 1, wherein: The detection channel (21B) and the injection channel (21A) are arranged to extend in the same direction.

7. The instant visual biological detection kit according to claim 5, wherein: The injection assembly (20) further comprises a side pressure piece (23), and the injection cylinder (21) is provided with a first limiting groove (21C) for the side pressure piece (23) to move; The first limiting groove (21C) is in communication with the injection channel (21A) and the outside world.

8. The instant visual biological detection kit according to claim 7, wherein: At least a portion of the side of the side pressure member (23) facing the injection cylinder (21) is provided with an open groove (23A), and the open groove (23A) penetrates the side pressure member (23) from top to bottom.

9. The instant visual biological detection kit according to claim 7, wherein: The side pressure piece (23) is provided with a second limiting groove (23B), and the injection cylinder (21) further comprises a limiting rod (213); The limiting rod (213) is arranged on the groove wall of the first limiting groove (21C) on the side facing away from the reaction seat (22), and the second limiting groove (23B) passes through the side pressure piece (23); The second limiting groove (23B) accommodates the limiting rod (213).

10. The instant visual biological detection kit according to any one of claims 1 to 9, wherein: The base (10) comprises a protrusion (11), the protrusion (11) is provided with a reaction limiting cavity (11A) and the first test tube insertion hole (11a), and the protrusion (11) is integrally formed with the base (10); The reaction limiting cavity (11A) is in communication with the first test tube insertion hole (11a) and the outside world; The reaction seat is located in the reaction limiting cavity (11A), and the side of the horizontal outer folded edge (222) facing away from the injection cylinder (21) abuts against the protrusion (11).

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