AAV variant capable of infecting inner ear
WO2025057943A1 Publication Date: 2025-03-20JUNTENDO EDUCATIONAL FOUNDATION +1
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Patent Information
- Application Number
- PCT/JP2024/032382
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-09-11
- Filing Date
- 2024-09-10
- Publication Date
- 2025-03-20
Abstract
The present invention provides: a nucleic acid encoding an adeno-associated virus (AAV) capsid protein variant containing a peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 7 or a peptide comprising an amino acid sequence having a structure that one or several amino acid residues are substituted, deleted, inserted and / or added in an amino acid sequence selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 7; and others.
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