Pleuromutilin wettable powder and preparation method therefor

By developing truncated leptin wettable powder, optimizing the formula and selecting appropriate wetting dispersants and fillers, the problem of insufficient prevention and efficacy of plant bacterial diseases in the prior art has been solved, and a more efficient and safer disease prevention and control effect has been achieved.

WO2025060728A1 Publication Date: 2025-03-27GUIZHOU UNIV
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Patent Information

Application Number
PCT/CN2024/110962
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-19
Filing Date
2024-08-09
Publication Date
2025-03-27

AI Technical Summary

Technical Problem

The existing technology lacks efficient and safe chemical pesticides to prevent and control plant bacterial diseases, especially the prevention of pathogens such as rice white leaf blight, rice bacterial strabular bacteria and citrus canker bacteria, resulting in huge losses in agricultural production.

Method used

A truncated pleurin wettable powder was developed to optimize the formulation by screening appropriate wetting dispersants and fillers, thereby improving the suspension rate and wettability of the original drug, thereby achieving better and broader spectrum activity against plant bacterial diseases.

Benefits of technology

The powder showed excellent antibacterial activity against bacterial diseases such as rice white leaf blight, rice bacterial stripe disease and citrus canker disease at a concentration of 200μg/mL. The EC50 value was better than that of the control drug, achieving the reduction and increase efficiency of chemical pesticides.

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Abstract

A pleuromutilin wettable powder and a preparation method therefor. The wettable powder comprises 5-25 wt% of pleuromutilin, 2-6 wt% of a wetting and dispersing agent, and the balance being a filler. The raw materials are crushed by a jet mill to a particle size of less than 325 meshes to obtain a 5-25% pleuromutilin wettable powder. The pleuromutilin wettable powder can be used for controlling various agricultural diseases such as xanthomonas oryzae pv. oryzae.
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